The image for day 231 of #LMB365 shows a sample of baker’s yeast labeled with fluorescent dyes. Three dyes (red, green and blue) create seven different colour combinations. These multi-coloured images are used as part of a method developed by John Briggs’ group in collaboration with colleagues from the Weizmann Institute of Science to perform multiple electron microscopy experiments in parallel. Yeast cells from different experiments get a unique colour-code. They are then pooled together in one sample for electron microscopy. By reading the colour-code, the experimenter can later work out which cell came from which experiment. http://jcb.rupress.org/content/218/8/2797
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