LMB 365 – Day 309

This image for day 309 of #LMB365 shows mouse fibroblasts where surface receptors have been clustered into spots using new synthetic polymers. Imaging is performed using sub-cellular light sheet microscopy, a state-of-the-art microscopy technique established at the LMB by James Manton, that is able to resolve cellular details with unprecedented temporal resolution. The Derivery lab is using this technique to study the molecular mechanisms of endocytosis and trafficking of receptors and cell fate determinants in cells.