On day 56 of #LMB365 ultraviolet rays from a special lamp shine brightly on frozen samples sitting on a bed of dry ice. In this biochemical experiment, the ultraviolet light induces crosslinks between a protein of interest and other unknown proteins surrounding it. This is being used by Manu Hegde’s group in Cell Biology to study how newly made proteins are guided to the correct location and assembled properly. This experiment is searching for the “guides” that direct this important cellular process.