Day 71 of #LMB365 shows what happens when you accidentally put a denaturing gel in the freezer rather than the fridge. Denaturing gels are used to separate double stranded DNA into single stranded DNA. KJ Patel’s group in the PNAC Division is studying DNA crosslinking agents and the repair of cross-linked DNA. They use the gels to confirm the presence of cross-linked DNA which won’t be able to separate into its individual strands and will consequently run slower through the gel.
MRC Laboratory of Molecular Biology
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