Electron cryo-microscopy (cryo-EM) is used across the LMB to determine protein structures. Part of the process for data collection involves screening grids in the electron microscope to check the grids have been produced correctly and the samples can be used. Sadly this is not always the case and on day 77 of #LMB365 “Sam” identified that the ice was too thin to be useful. To cheer himself up he wrote his name in the holes of the EM grid by melting the ice with the electron beam.
MRC Laboratory of Molecular Biology
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