Using cryo-EM, researchers in the groups of Sjors Scheres and Michel Goedert determined the atomic structure of tau filaments that were extracted from the brain of an individual with Alzheimer’s disease. The resulting structure is shown on day 82 of #LMB365. Understanding the molecular mechanisms of tau aggregation in neurodegenerative disease may be important in finding a cure.
MRC Laboratory of Molecular Biology
One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.