LMB 365 – Day 82

Using cryo-EM, researchers in the groups of Sjors Scheres and Michel Goedert determined the atomic structure of tau filaments that were extracted from the brain of an individual with Alzheimer’s disease. The resulting structure is shown on day 82 of #LMB365. Understanding the molecular mechanisms of tau aggregation in neurodegenerative disease may be important in finding a cure.