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LMB research details first step towards writing human genomes from scratch

Published on 9 December, 2025

Roger Highfield, Science Director at the Science Museum, explains the wider significance of new research from the LMB’s PNAC Division which describes a pipeline to manipulate human chromosomes without genetic damage. The work, led by Julian Sale and Jason Chin as part of a wider Synthetic Human Genome (SynHG) project backed by the Wellcome Trsut, is the first step towards their ultimate goal of writing human genomes from scratch. More…