• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

  • Home
  • About LMB
  • Research
  • Research Groups
  • Students
  • Recruitment
  • Life at the LMB
  • Achievements
  • News & Events
Home > Image365 > LMB365 – Day 343

LMB365 – Day 343

Published on 9 December, 2019

The technique of Hydrogen Deuterium exchange/Mass Spectrometry can be used to highlight regions of a protein’s structure that change upon binding to another protein or ligand. Day 343 of #LMB365 shows a butterfly plot or chart, showing the incorporation of deuterium into a protein over time (orange shortest, black the longest period). The upper half of the plot shows incorporation by the protein in complex, while the lower area indicates the incorporation by the protein alone. The plot can give insights into regions of intrinsic disorder as well as regions of higher order structure such as alpha-helices and beta-sheets.

Primary Sidebar

Search

  • Privacy & Cookies
  • Contact Directory
  • Freedom of Information
  • Site Map
Find Us
©2023 MRC Laboratory of Molecular Biology,
Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. 01223 267000

The MRC is part of UK Research and Innovation

Contact Us