Nature’s 150th anniversary issue celebrates Georges Köhler, Cesar Milstein and Greg Winter’s pioneering role in the rise of monoclonal antibodies

This Nature opinion piece recounts the dramatic impact of the pivotal 1975 paper by Köhler–Milstein on biomedical and, specifically, immunological research, which was propelled by scientific developments that occurred around the time the paper appeared. It also chronicles the research on monoclonal antibodies over the years all the way to Greg Winter’s research, which features in the story as a podcast. More