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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > LMB In The News > Towards preventing neurodegenerative diseases

Towards preventing neurodegenerative diseases

Published on 6 May, 2015

Research led by the LMB’s Anne Bertolotti has discovered a selective inhibitor of a phosphatase enzyme that could prevent protein misfolding diseases. The scientists showed that the new molecule, dubbed Sephin1, countered the effects of aggregating proteins in mouse models of amyotrophic lateral sclerosis and Charcot-Marie-Tooth disease, and might do so for other neurodegenerative disorders. More…

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