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Using cryo-EM to solve the structure of a protein complex critical for gene expression

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Lori Passmore and her group have used electron cryo-microscopy to solve the structure of CPF, a protein complex critical for gene expression. Understanding the structure and function of intact CPF, and how it is assembled, has been a central question in the field of gene expression for decades. [A Log-in or subscription may be required to view this article from the host site: https://www.drugtargetreview.com/news/27088/cryo-electron-microscopy-cpf/]