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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Image365

LMB 365 – Day 299

Published on 26 October, 2019

This photo for day 299 of #LMB365 shows some of the LMB’s Domestic Services team celebrating James’ birthday. The LMB has many long-term members of staff and these 3 between them have racked up over 50 years of loyal service.

LMB 365 – Day 298

Published on 25 October, 2019

During the last year, over 4,500 initial crystallisation screens were used at the LMB to test macromolecular samples of interest. Further screens are often required for optimisation purposes. The corresponding trays containing the crystallisation experiments are stored in temperature-controlled rooms as seen here on day 298 of #LMB365.

LMB 365 – Day 297

Published on 24 October, 2019

Day 297 of #LMB365 is a screenshot from our internal “Bee Cam”. It shows our resident beekeeper Geoff putting on a feeder of sugar syrup for the LMB’s bees to build up stores for the winter. The bees have also been treated for mites so hopefully they will be well until next year.

LMB 365 – Day 296

Published on 23 October, 2019

The annual Perutz Student Prize has been awarded recently and the winners photographed in the Max Perutz Lecture Theatre under Max’s watchful eye as recorded here on day 296 of #LMB365 by Anne Bertolotti. Watch this space to find out about the winners…

LMB 365 – Day 295

Published on 22 October, 2019

Day 295 of #LMB365 shows the structure of a human GABAA receptor in a membrane nanodisc, bound to alprazolam/Xanax, solved in Radu Aricescu’s group. GABAA receptors are essential for brain function and also targets for major clinical drugs including general anaesthetics, benzodiazepines and sleeping pills.

LMB 365 – Day 294

Published on 21 October, 2019

Day 294 of #LMB365 shows a bottle of Caveat mTOR, a hot sauce made from chillies grown on the windowsill of Roger Williams’ Lab. After picking, the chillies are lacto-fermented for a week with onion, garlic, and a few herbs and spices before blending, seasoning and bottling. The protein ‘mTOR’ is a key target of investigation in the Williams lab, hence the hilarious pun which gives the sauce its name.

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