Image365

This image for day 245 of #LMB365 is aview of the western end of the LMB taken by Ivan Rosa e Silva. The glass is cleaned annually which, on a lovely clear day, means all the reflections in the glass show off the beauty of the building.

On day 244 of #LMB365 is Richard Henderson who #OTD in 1974 started his research group at the LMB. He is pictured here in the 1970s with the X-ray camera rotating anode. Richard would predominately use electron microscopy for his work on membrane proteins and received the Nobel Prize for Chemistry in 2017 for his work on developing electron cryomicroscopy (cryoEM)

Day 243 of #LMB365 shows an SDS-PAGE cake baked by Jaslyn Wong in Roger Williams’ group in the PNAC Division. She hoped to motivate her colleagues to keep trying to get crystalsof Rag proteins that activate the cancer drug target mTOR. Protein crystallisation has been, and is still used by many groups across the LMB to determine protein structure.

Day 242 of #LMB365 by Dana Galili in Greg Jefferis’ group in the Neurobiology Division shows interactions between fruit flies. These videos are automatically tracked using computer vision and machine learning methods, to closely inspect their social behaviour patterns. By manipulating the activity of specific neurons in behaving flies, the researchers study the logic of the neuronal circuits underlying sex-specific behaviours

The LMB Group Leaders recently went on a 2-day retreat to discuss their vision for the future of their research and the LMB as a whole. This included discussions about matters impacting on staff, particularly women in science. The female group leaders present took the opportunity to get this photo taken for day 241 of #LMB365 in between sessions.

Ketan Malhotra from Anne Bertolotti’s group and Manuel Carminati from Lori Passmore’s group recently prepped 62 litres of E.coli to harvest their protein for purification and structure determination. Day 240 of #LMB365 shows the resulting 50 ml falcon tubes, which each contain 2 litres of cells