Day 21 #LMB365 is a Max Perutz Word Cloud. Max was the founder and first Chairman of the MRC Unit that became the LMB. He determined the structure of haemoglobin and won the 1962 Nobel Prize @NobelPrize, jointly with John Kendrew, for their work on the structure of proteins
Image365
LMB 365 – Day 20
Day 20 of #LMB365 is a model of myoglobin displayed in LMB’s atrium and made for LMB Nobel Laureate, John Kendrew @NobelPrize. It is an oxygen storing protein found in muscles, in particular in ocean and diving mammals, and was the first protein structure to be determined
LMB 365 – Day 19
Day 19 of #LMB365 shows a DNA fibre assay from KJ Patel’s group in PNAC. Antibodies are used to label DNA synthesis replication tracts (green & blue) and the rest of the DNA (pink). This is used to study dynamics of the DNA replication fork in the context of DNA repair defects
LMB 365 – Day 18
Day 18 of #LMB365 shows pronuclear injection of a transgenic DNA solution into a fertilised mouse egg. The egg is held in place on a pulled glass pipette by suction. The new transgenic mouse strains are used to study human diseases and potentially identify targets for treatments
LMB 365 – Day 17
Day 17 of #LMB365 is the sculpture ‘What Mad Pursuit’ by Kindra Crick @K_Crick, the granddaughter of Francis Crick. It depicts the DNA double helix for which the 1962 Nobel Prize @NobelPrize was awarded. It includes blackboard drawings Francis used to help solve scientific ideas
LMB 365 – Day 16
On day 16 of #LMB365 Laura Pellegrini @laupellegrini from Madeline Lancaster’s group @MinibrainLab in Cell Biology @CellBiol_MRCLMB has made a collage of human cerebral organoid ventricular buds. The ventricular buds are used to study the development of human cerebral cortex