The Nobel prize in chemistry has been awarded to three scientists, Jacques Dubochet, Joachim Frank and the LMB’s Richard Henderson, for developing a technique to produce images of the molecules of life frozen in time. The technique, called cryo-electron microscopy, allowed biomolecules to be visualised in their natural configuration for the first time, triggering a “revolution in […]
LMB In The News
Leprosy turns the immune system against itself
An international team of scientists, including Lalita Ramakrishnan’s group in the University of Cambridge Molecular Immunity Unit, based at the LMB, have discovered that Leprosy hijacks our immune system, turning an important repair mechanism into one that causes potentially irreparable damage to our nerve cells. More…
Protein localization inside cells
Ramanujan Hegde talks about protein localization inside cells and quality control of this process. More…
Tau filaments from the Alzheimer’s brain revealed
Tau filaments isolated from an Alzheimer’s brain are the latest, high-profile exploit of cryo-electron microscopy. Crafting a technique that has become his claim to fame, Sjors Scheres of the MRC Laboratory of Molecular Biology in Cambridge, England, teamed up with Michel Goedert, also at MRC, to solve 3.4-Angstrom resolution structures of both straight and paired […]
Exploring the incredible transport system inside our cells
Simon Bullock discusses his research into intracellular trafficking of RNA, and talks about the importance of science outreach in inspiring the next generation of young scientists. More…
Sharp focus on Alzheimer’s may help target drugs
Abnormal deposits that build up in the brain during Alzheimer’s have been pictured in unprecedented detail in research led by Sjors Scheres and Michel Goedert. More…