Fabrice Gorrec from the LMB has published developments related to MORPHEUS II – a protein crystallization screen. He has demonstrated that additives selected from the PDB that are under-represented in traditional screens can be combined to formulate suitable and useful conditions, not only for crystallization but the overall structure determination process. More
LMB In The News
New details of the transmission of stimuli in living organisms unveiled
A team lead by Dmitry Veprintsev from the Paul Scherrer Institute (PSI) and ETH Zurich together with Madan Babu Mohan’s group at LMB and the pharmaceutical company Roche provide new details of how the activation of G-protein-coupled receptors takes place and demonstrate that only a few amino acids have a major influence on GPCR function. […]
Monoclonal antibodies: the invisible allies that changed the face of medicine
They are tiny magic bullets that are quietly shaping the lives of millions of patients around the world. Monoclonal antibodies are contained in six out of ten of the world’s bestselling drugs, helping to treat everything from cancer to heart disease to asthma. The technique for producing them was first published 40 years ago by […]
The origin of biological clocks
Review of research, including that of the LMB’s John O’Neill, on the evolutionary story of circadian rhythms. More…
Harnessing computer power to understand biology
In an interview for Science Careers, former LMB Group Leader Sarah Teichmann talks about how she was inspired by computational biology by Cyrus Chothia, with whom she did her PhD. She also shares how she gained her skills and abilities and what doors they opened to her. More…
How to grow a brain
Being able to grow rudimentary brain tissue in the lab means that researchers can study organ development and disease. But how do you go from stem cells to a ‘mini-brain’? New LMB group leader Madelaine Lancaster’s research is highlighted in a report by the Long+Short magazine’s Ben Martynoga on the latest MRC Insight blog. More…