The pioneering career of LMB Alumnus Joan Steitz, currently Sterling Professor of Molecular Biophysics and Biochemistry at Yale University is featured by CTNOW, looking at her work and how Joan’s time at the LMB studying ribosomes led to her important discoveries in RNA research. More…
LMB In The News
ISCB Senior Scientist Award for Cyrus Chothia
A look at the career of LMB’s Cyrus Chothia and his work on the structures and functions of proteins, following announcement of his ISCB Senior scientist award. More…
New Approach To Control Enzyme Function In Cells
A new technique, devised by Jason Chin’s group, could make it easier to target and inhibit specific enzymes and other proteins in cells and to turn that regulation on and off at will with light. Bioorthogonal ligand tethering, or BOLT, has been used to create an inhibitor that can regulate the activity of a target […]
A new genetic switch uncovered in the long genes expressed in our brain
Jernej Ule, former LMB group leader, and Vincent Plagnol from UCL have discovered a new mechanism for ‘splicing-based’ gene regulation, with possible implications for brain-related disorders. Jernej began this research when he was in the LMB’s Structural Studies Division. More…
Did frosts lead to life on Earth?
Large RNA molecules can be assembled from basic biochemical building blocks during cycles of freezing and thawing. This breakthrough from Philipp Holliger’s group at the LMB reinforces the possibility that RNA was responsible for both molecular heredity and metabolism in primordial biochemistry. More…
Making Sense of the Chemistry That Led to Life on Earth
An article in the New York Times highlights the work of John Sutherland, a group leader at the LMB, who has determined a possible chemical pathway to produce the starting materials of life. In his laboratory he tested all the chemical reactions needed to make precursors of lipids, nucleotides and amino acids, the building blocks […]