This impressionistic glimpse of the LMB on a sunny day for #LMB365 day 172 was created by Xiaohan Li. In LMBers’ eyes, science can always be artistic.
LMB 365 – Day 172
LMB welcomes Kelly Nguyen as a new Group Leader
The LMB is delighted to announce the appointment of Kelly Nguyen as a Group Leader in the LMB’s Structural Studies Division. She will take up her post in August 2019. Kelly will be working on the mechanism of telomere maintenance. Telomeres are located at the ends of eukaryotic chromosomes and play essential roles in maintaining genome […]
LMB 365 – Day 171
Day 171 of #LMB365 shows Richard Henderson with a model of the membrane protein, bacteriorhodopsin. Richard used high-resolution electron cryo-microscopy, developing new methods for analysing micrographs from tilted specimens, in his landmark paper, published on this day in 1990. The Nobel Committee cited this paper when Richard was awarded the 2017 Nobel Prize for Chemistry. Reference: Richard Henderson et al. Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy. Journal of Molecular Biology. 213:899-929, 1990
Functionalized graphene sheets on gold grids aid structure determination by electron cryo-microscopy
With the ‘resolution revolution’ of recent years, it should in principle be possible to determine atomic resolution structures of any proteins using electron cryo-microscopy (cryo-EM). However, in practice, preparation of frozen samples that are suitable for high resolution imaging is a barrier to progress. Christopher Russo’s group in the LMB’s Structural Studies Division have now […]
LMB 365 – Day 170
On day 170 of #LMB365 this LMBee is hard at work on the Titan Krios microscope in the LMB’s EM Facility doing its bit to automate high-throughput data collection for cryo-EM.
LMB 365 – Day 169
The LMB Estates & Facilities team gets involved in many projects, both big and small. Day 169 of #LMB365 shows the culmination of months of work to replace the old boilers (red) with new boilers (silver) at our facility at Babraham. The work had to be carried out at a time that disruption to science was kept to a minimum and as anticipated things went very smoothly.