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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > Newly identified quality control mechanism of RNA Polymerase II transcription

Newly identified quality control mechanism of RNA Polymerase II transcription

Newly identified quality control mechanism of RNA Polymerase II transcription

Published on 11 December, 2024

Ana Tufegdžić Vidaković’s group, in the LMB’s PNAC Division, have worked with Scott Berry’s group, at the University of New South Wales, to identify the mechanism cells use to regulate gene expression via control of quality and quantity of Pol II molecules.

Marta Shahbazi joins EMBO Young Investigator Programme

Published on 3 December, 2024

Marta Shahbazi, Group Leader in the LMB’s Cell Biology Division, joins the global community of early-career researchers, with training, mentorship and networking opportunities from EMBO.

2024 César Milstein Lecture to be delivered by Mónica Bettencourt-Dias

Published on 2 December, 2024

Mónica Bettencourt-Dias will deliver the Milstein Lecture on 9th December 2024 on the topic ‘Centrioles in homeostasis, disease and evolution: tiny organelles, multiple and critical functions’.

Discovery of a factor that accelerates protein deliveries to the endoplasmic reticulum

Published on 29 November, 2024

Huping Wang and Manu Hegde, in the LMB’s Cell Biology Division, have found a factor that helps nascent secretory and membrane proteins quickly access the protein translocation machinery when they arrive at the endoplasmic reticulum.

Advancing technologies take centre stage at Next Generation Biophysics Symposium

Published on 27 November, 2024

The LMB was delighted to once again host the Next Generation Biophysics where several distinguished speakers discussed cutting-edge biophysical techniques.

Cryo-ET reveals new molecular insights into tau pathology in Alzheimer’s disease

Published on 26 November, 2024

Benjamin Ryskeldi-Falcon’s group in the LMB’s Neurobiology Division have used cryo-ET to discover that tau filaments are tethered to the membranes of extracellular vesicles in Alzheimer’s disease. These findings introduce membrane tethering of amyloid filaments as a potential target to interfere with their accumulation in disease.

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