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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > Wesley Sundquist awarded 2024 Horwitz Prize together with Scott Emr for discovering the ESCRT pathway

Wesley Sundquist awarded 2024 Horwitz Prize together with Scott Emr for discovering the ESCRT pathway

Wesley Sundquist awarded 2024 Horwitz Prize together with Scott Emr for discovering the ESCRT pathway

Published on 19 September, 2024

LMB 1988 – 1992, Scientific Visitor, Postdoctoral Fellow, Structural Studies Congratulations to Wesley Sundquist, awarded the 2024 Louisa Gross Horwitz Prize together with Scott Emr for discovering the ESCRT (Endosomal Sorting Complexes Required for Transport) pathway and revealing how it works. Wes and colleagues discovered how and why ESCRT complexes are required for HIV replication […]

The LMB welcomes new Group Leader Joergen Kornfeld

Published on 17 September, 2024

Joergen Kornfeld’s group in the LMB’s Neurobiology Division will investigate the connectomics of learned behaviour using the zebra finch as a model.

New potential therapy for neurodegeneration removes tau aggregates and improves motor function

Published on 13 September, 2024

Leo James’ group, in the LMB’s PNAC Division, have worked with Will McEwan’s group at the UK Dementia Research Institute to design two new therapeutics which harnesses cellular machinery to remove tau aggregates, improving motor skills in mice affected by neurodegenerative disease.

Members of LMB fundraise and take part in first CBC 5km, 10km and Fun Run

Published on 13 September, 2024

Members of the LMB joined almost 700 fellow runners to take part in the first Cambridge Biomedical Campus 5km, 10km and Fun Run on Sunday 1st September. LMB runners included Adam Mayes, who raised over £1000 for Bike the UK for MS, running in an LMBee costume. The runners medal featured the DNA double helix […]

Unprecedented heteromeric amyloid structure in neurodegenerative disease

Published on 11 September, 2024

Surprising advance to our understanding of neurodegenerative diseases, as Diana Arseni and Benjamin Ryskeldi-Falcon in the LMB’s Neurobiology Division find that frontotemporal lobar degeneration Type C filaments include both annexin A11 and TDP-43 in a unique heteromeric structure.

Diana Arseni appointed Group Leader in the LMB’s Neurobiology Division

Published on 11 September, 2024

Diana Arseni’s research group in the LMB’s Neurobiology Division will study mechanisms of brain health, ageing and disease focusing on the lysosomal protein TMEM106B.

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