Study by Madeline Lancaster and collaborators at IMBA is one of the first attempts to combine organoids with bioengineering. More…
Building better brains: A bioengineered upgrade for organoids
A new view of the spliceosome
Kiyoshi Nagai’s group capture important state of cellular machine responsible for making humans more complex than worms. More…
Dynamic structure of human DNA repair enzyme, ATM, revealed
The DNA in cells is constantly damaged by both internal activities of the cell and by external factors such as ionising radiation. In order to function correctly, this damage must be repaired, or if it cannot be repaired, the cell must be killed to prevent development of diseases such as cancer. The large protein kinase, […]
The key to GPCR-G protein selectivity
G protein-coupled receptors (GPCRs) form the largest family of membrane-protein receptors and drug targets. With over 800 different family members in humans, GPCRs regulate diverse intracellular signalling cascades in different cell types, tissues and organ systems. Whilst GPCRs sense a plethora of environmental stimuli, the appropriate cellular response is primarily triggered by binding to four […]
Mo Moffateh’s winning science image
Mo Moffateh’s image of beautifully repeated segments of Drosophila melanogaster embryonic nervous system, picked as joint third in British Society for Cell Biology’s 2017 winning images. More…
Anne Bertolotti elected Fellow of the UK Academy of Medical Sciences
Anne Bertolotti, group leader in the LMB’s Neurobiology Division, has been elected a Fellow of the UK Academy of Medical Sciences for her contribution to understanding protein quality control systems and their therapeutic manipulations. The Academy represents the diverse spectrum of medical sciences – from basic research through clinical application to healthcare delivery. Their mission […]