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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > Enhanced understanding of how HIV-1 infect our cells

Enhanced understanding of how HIV-1 infect our cells

Enhanced understanding of how HIV-1 infect our cells

Published on 27 January, 2023

The Cambridge Independent reports on a study from Leo James’ group in the LMB’s PNAC Division which has identified the process whereby HIV-1 builds its capsid using the metabolite IP6 which is captured from cells with a net-like protein lattice. More…

2023 César Milstein Lecture to be given by Denis Duboule

Published on 19 January, 2023

Denis Duboule will deliver the Milstein Lecture on 26th Janurary 2023 on the topic ‘Understanding the Hox timer by using mammalian pseudo-embryos’.

The LMB donates over £1500 to the Arthur Rank Hospice Charity

Published on 18 January, 2023

The annual LMB Christmas charity raffle, and Craft and Chatter group Christmas sale, has raised £1526 for the Arthur Rank Hospice Charity.

Teresa Wallman (1974 – 2023)

Published on 18 January, 2023

Teresa Wallman, LMB Archive Assistant and previously joint Library and Archive Assistant for over 12 years, died on Thursday 5th January, at the age of 48

HIV-1 needs the cell metabolite IP6 to build its capsid and infect cells

Published on 9 January, 2023

In an international collaboration led by Leo James’ group, researchers have discovered that HIV-1 builds its capsid using a metabolite called IP6 that it captures from cells with a net-like protein lattice. Disabling this capture mechanism prevents capsid construction and renders HIV-1 non-infectious.

Seismic progress possible for cancer research

Published on 9 January, 2023

KJ Patel shares his optimism for progression in treatment and preventative measures for cancer within his current role as Chief Scientist at Cancer Research UK (CRUK), which began in October 2022. More…

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