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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > Protein sorting in the Golgi: Should I stay or should I go?

Protein sorting in the Golgi: Should I stay or should I go?

Protein sorting in the Golgi: Should I stay or should I go?

Published on 6 October, 2025

Providing order amongst constant cargo traffic: Sean Munro’s group in the LMB’s Cell Biology Division and John Briggs’ group at the Max Planck Institute of Biochemistry, identify how GOLPH3 enables COPI vesicles to distinguish between Golgi resident and proteins bound for the endoplasmic reticulum.

Lori Passmore received honorary awards from Cambridge and Aarhus Universities

Published on 2 October, 2025

Lori Passmore, Group Leader and Joint Head of the LMB’s Structural Studies Division, has been appointed Honorary Professor of the University of Cambridge and received an Honorary Doctorate from Aarhus University in Denmark. Lori is an Official Fellow of Clare Hall College, Cambridge and has collaborated closely with Aarhus University since launching her independent research […]

Team of the Year for LMB’s Biological Services Group in the Janet Wood Innovation Awards

Published on 29 September, 2025

The award recognises the quarantine unit for their outstanding contribution to research and animal welfare. The dedicated team carries out a wide range of regulated procedures and their proactive approach to refinement has led to the introduction of improved surgical techniques and the use of extra enrichment. More…

Life Sciences Breakthrough of the Year for Melina Schuh’s work to visualise ovulation

Published on 25 September, 2025

LMB 2008-2016, Senior Investigator Scientist, Group Leader, Cell Biology Melina Schuh’s work has been announced as the 2025 Science Breakthrough of the Year in the Life Sciences category by the Falling Walls Foundation. The accolade recognises her group’s achievement to visualise the entire ovulation process in mouse follicles in real-time utilising a newly developed live […]

Generating paired helical filaments (PHFs) in vitro presents new opportunities for Alzheimer’s research

Published on 19 September, 2025

Research spearheaded by Sofia Lövestam in Michel Goedert and Sjors Scheres’ groups has identified a combination of 12 residues in tau which, when mutated in vitro, prompt the formation of paired helical filaments (PHFs), the distinctive hallmark of advanced Alzheimer’s disease. Interestingly, in the engineered tau, named PAD12, the residues in question are all outside […]

Sarah Teichmann: Science always wins if we work together

Published on 15 September, 2025

LMB 1996-1999, 2001-2013, PhD Student, Group Leader, Structural Studies The Journal of Experimental Medicine spoke to Sarah Teichmann about expanding beyond academic science in your career, dealing with uncertainty in the workplace, and being able to carve out time for yourself despite having multiple demands on your time. More…

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