John Briggs’ group has provided the first description of HIV-1 matrix protein structures determined within both immature and mature authentic virus particles, showing how they rearrange on maturation of the virus ahead of infection of another cell.
Unexpected matrix protein rearrangements seen in structures from intact HIV-1 virus
A colourful welcome back for the LMB Arts and Crafts Show
The LMB Arts and Crafts Show: showcasing the creative talents of the LMB
Testing the capacity for intracellular antibodies to neutralise SARS-CoV-2
While infected with SARS-CoV-2, our immune systems generate antibodies against both Spike (S) and Nucleoprotein (N). However, standard tests only show neutralisation for S-antibodies. Leo James’ group has developed a new assay that measures anti-viral activity of N-antibodies.
The LMB welcomes Tanmay Bharat as a new Group Leader
Tanmay Bharat is returning to the LMB, this time as a Group Leader in the Structural Studies Division, where he will continue his research into cell surfaces of prokaryotes.
How Electrical Engineer David Street supports the LMB’s science behind the scenes
In highlighting non-traditional jobs which support research and innovation, UKRI have profiled David Street, a member of the LMB’s Estates and Facilities team. Here, David discusses building maintenance, the team’s 24/7 ‘on call’ support service, and installing a new Scientific Computing Server Room. More…
A new generation of detector is set to advance low energy cryo-EM
A new Quantum C100 detector, optimised for 100 keV low-energy cryo-EM, has been developed by STFC in partnership with the Rosalind Franklin Institute and LMB. Brought to market by Quantum Detectors with the aim of increasing access to cryo-EM technology, the innovative technology was developed in consultation with Richard Henderson and Chris Russo, with hands-on […]