Nearly half of the human genome is composed of various forms of DNA repeat. Pierre Murat in Julian Sale’s group has revealed a mechanism that safeguards the genome from pathological expansion of one group of DNA repeats known as STRs.
A simple, novel mechanism to safeguard the integrity of the human genome
Discovery of a chaperone for membrane proteins
Proteins embedded in the cellular membrane perform a wide variety of necessary tasks. Most are folded into complex shapes that pass back and forth across the membrane. Patrick Chitwood and Manu Hegde have discovered a new type of chaperone that helps them assemble correctly.
Studying the spike protein of SARS-CoV-2
John Briggs’ group has led two new studies of the spike (S) protein that mediates binding to the receptor ACE2 and is the dominant target of the immune system, with applications for development of vaccines and diagnostic tests.
Championing non-aversive mouse handling
How one animal technician led culture change in the LMB animal facility – perseverance and communication are key.
Hayley Sharpe wins a 2020 Lister Institute Research Prize
Hayley Sharpe, a former PhD student with Sean Munro’s group in the Cell Biology Division, is one of four researchers to be awarded a 2020 Lister Institute Research Prize. The Lister Institute awards a handful of high value, prestigious research prizes every year to early-career biomedical scientists who have demonstrated outstanding performance and potential. This […]
From metastasis to your favourite biscuit: connecting with school students from home
For 12 weeks since late April, more than 20 LMB scientists have been answering questions from students all over the UK on I’m a Scientist, Stay at Home.