Szeto ACH, Clark PA, Ferreira ACF, Heycock M, Griffiths EL, Jou E, Mannion J, Luan SL, Storrar S, Knolle MD, Kozik P, Jolin HE, Fallon PG, McKenzie ANJ.
Mef2d potentiates type-2 immune responses and allergic lung inflammation
Science Science. 2024 Jun 28;384(6703):eadl0370. doi: 10.1126/science.adl0370. Epub 2024 Jun 28.DOI: 10.1126/science.adl0370
PMID: 38935708
PMCID:
Date of Paper: 28/06/2024
Division: Protein & Nucleic Acid ChemistryKay RR, Lutton JE, King JS, Bretschneider T.
Making cups and rings: the 'stalled-wave' model for macropinocytosis
Biochemical Society Transactions Biochem Soc Trans. 2024 Jun 27:BST20231426. doi: 10.1042/BST20231426. Online ahead of print.DOI: 10.1042/BST20231426
PMID: 38934501
PMCID:
Date of Paper: 27/06/2024
Division: Cell BiologyLawson CL, Kryshtafovych A, Pintilie GD, Burley SK, Černý J, Chen VB, Emsley P, Gobbi A, Joachimiak A, Noreng S, Prisant MG, Read RJ, Richardson JS, Rohou AL, Schneider B, Sellers BD, Shao C, Sourial E, Williams CI, Williams CJ, Yang Y, Abbaraju V, Afonine PV, Baker ML, Bond PS, Blundell TL, Burnley T, Campbell A, Cao R, Cheng J, Chojnowski G, Cowtan KD, DiMaio F, Esmaeeli R, Giri N, Grubmüller H, Hoh SW, Hou J, Hryc CF, Hunte C, Igaev M, Joseph AP, Kao WC, Kihara D, Kumar D, Lang L, Lin S, Maddhuri Venkata Subramaniya SR, Mittal S, Mondal A, Moriarty NW, Muenks A, Murshudov GN, Nicholls RA, Olek M, Palmer CM, Perez A, Pohjolainen E, Pothula KR, Rowley CN, Sarkar D, Schäfer LU, Schlicksup CJ, Schröder GF, Shekhar M, Si D, Singharoy A, Sobolev OV, Terashi G, Vaiana AC, Vedithi SC, Verburgt J, Wang X, Warshamanage R, Winn MD, Weyand S, Yamashita K, Zhao M, Schmid MF, Berman HM, Chiu W.
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge
Nature Methods Nat Methods. 2024 Jun 25. doi: 10.1038/s41592-024-02321-7. Online ahead of print.DOI: 10.1038/s41592-024-02321-7
PMID: 38918604
PMCID:
Date of Paper: 25/06/2024
Division: Structural StudiesAyagama T, Charles PD, Bose SJ, Boland B, Priestman DA, Aston D, Berridge G, Fischer R, Cribbs AP, Song Q, Mirams GR, Amponsah K, Heather L, Galione A, Herring N, Kramer H, Capel RA, Platt FM, Schotten U, Verheule S, Burton RAB.
Compartmentalization proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation
iScience iScience. 2024 Mar 28;27(6):109609. doi: 10.1016/j.isci.2024.109609. eCollection 2024 Jun 21.DOI: 10.1016/j.isci.2024.109609
PMID: 38827406
PMCID: PMC11141153
Date of Paper: 21/06/2024
Division: Cell BiologyHarasimov K, Gorry RL, Welp LM, Penir SM, Horokhovskyi Y, Cheng S, Takaoka K, Stützer A, Frombach AS, Taylor Tavares AL, Raabe M, Haag S, Saha D, Grewe K, Schipper V, Rizzoli SO, Urlaub H, Liepe J, Schuh M.
The maintenance of oocytes in the mammalian ovary involves extreme protein longevity
Nature Cell Biology Nat Cell Biol. 2024 Jun 20. doi: 10.1038/s41556-024-01442-7. Online ahead of print.DOI: 10.1038/s41556-024-01442-7
PMID: 38902423
PMCID:
Date of Paper: 20/06/2024
Division: Cell BiologyMateo-Bonmatí E, Montez M, Maple R, Fiedler M, Fang X, Saalbach G, Passmore LA, Dean C.
A CPF-like phosphatase module links transcription termination to chromatin silencing
Molecular Cell Mol Cell. 2024 Jun 20;84(12):2272-2286.e7. doi: 10.1016/j.molcel.2024.05.016. Epub 2024 Jun 7.DOI: 10.1016/j.molcel.2024.05.016
PMID: 38851185
PMCID:
Date of Paper: 20/06/2024
Division: Structural StudiesLindhout FW, Krienen FM, Pollard KS, Lancaster MA.
A molecular and cellular perspective on human brain evolution and tempo
Nature Jun;630(8017):596-608DOI: 10.1038/s41586-024-07521-x
PMID: 38898293
PMCID:
Date of Paper: 19/06/2024
Division: Cell BiologyLewis AJO, Zhong F, Keenan RJ, Hegde RS.
Structural analysis of the dynamic ribosome-translocon complex
Elife Jun 18;13:RP95814DOI: 10.7554/eLife.95814
PMID: 38896445
PMCID: PMC11186639
Date of Paper: 18/06/2024
Division: Cell BiologyBacioglu M, Schweighauser M, Gray D, Lövestam S, Katsinelos T, Quaegebeur A, van Swieten J, Jaunmuktane Z, Davies SW, Scheres SHW, Goedert M, Ghetti B, Spillantini MG.
Cleaved TMEM106B forms amyloid aggregates in central and peripheral nervous systems
Acta Neuropathologica Communications Jun 17;12(1):99DOI: 10.1186/s40478-024-01813-z
PMID: 38886865
PMCID: PMC11181561
Date of Paper: 17/06/2024
Division: Structural Studies , NeurobiologyLuo J, Yu Y, Wang K, He S, Wang L, Liang F, Chin JW, Tang S.
Capturing acyl-enzyme intermediates with genetically encoded 2,3-diaminopropionic acid for hydrolase substrate identification
Nature Protocols 10.1038/s41596-024-01006-xDOI: 10.1038/s41596-024-01006-x
PMID: 38867073
PMCID:
Date of Paper: 12/06/2024
Division: Protein & Nucleic Acid ChemistryKimanius D, Jamali K, Wilkinson ME, Lövestam S, Velazhahan V, Nakane T, Scheres SHW.
Data-driven regularization lowers the size barrier of cryo-EM structure determination
Nature Methods 10.1038/s41592-024-02304-8DOI: 10.1038/s41592-024-02304-8
PMID: 38862790
PMCID: PMC11239489
Date of Paper: 11/06/2024
Division: Structural StudiesXu J, Janicki MJ, Szabla R, Sutherland JD.
Prebiotic synthesis of dihydrouridine by photoreduction of uridine in formamide
Chemical Communications 10.1039/d4cc01823kDOI: 10.1039/d4cc01823k
PMID: 38896044
PMCID: PMC11223185
Date of Paper: 10/06/2024
Division: Protein & Nucleic Acid ChemistryMartin-Solana E, Diaz-Lopez I, Mohamedi Y, Ventoso I, Fernandez JJ, Fernandez-Fernandez MR.
Progressive alterations in polysomal architecture and activation of ribosome stalling relief factors in a mouse model of Huntington's diseas
Neurology of Disease Jun 1;195:106488DOI: 10.1016/j.nbd.2024.106488
PMID: 38565397
PMCID:
Date of Paper: 01/06/2024
Division: Cell BiologyLiu Z, Jiang CZ, Bond AD, Tosca NJ, Sutherland JD.
Manganese(II) promotes prebiotically plausible non-enzymatic RNA ligation reactions
Chemical Communications (Cambridge) Chem Commun (Camb). 2024 Jun 20;60(51):6528-6531. doi: 10.1039/d4cc01086h.DOI: 10.1039/d4cc01086h
PMID: 38836405
PMCID: PMC11189027
Date of Paper: 30/05/2024
Division: Protein & Nucleic Acid ChemistryHegde RS, Keenan RJ.
A unifying model for membrane protein biogenesis
Nature Structural & Molecular Biology 10.1038/s41594-024-01296-5DOI: 10.1038/s41594-024-01296-5
PMID: 38811793
PMCID:
Date of Paper: 29/05/2024
Division: Cell Biologyvon Kügelgen A, Cassidy CK, van Dorst S, Pagani LL, Batters C, Ford Z, Löwe J, Alva V, Stansfeld PJ, Bharat TAM.
Membraneless channels sieve cations in ammonia-oxidizing marine archaea
Nature 10.1038/s41586-024-07462-5DOI: 10.1038/s41586-024-07462-5
PMID: 38811725
PMCID:
Date of Paper: 29/05/2024
Division: Protein & Nucleic Acid ChemistryRodríguez-Rodríguez N, Rosetti F, Crispín JC.
CD8 is down(regulated) for tolerance
Trends in Immunology S1471-4906(24)00100-5DOI: 10.1016/j.it.2024.04.012
PMID: 38782625
PMCID:
Date of Paper: 22/05/2024
Division: Protein & Nucleic Acid ChemistrySeinkmane E, Edmondson A, Peak-Chew SY, Zeng A, Rzechorzek NM, James NR, West J, Munns J, Wong DC, Beale AD, O'Neill JS.
Circadian regulation of macromolecular complex turnover and proteome renewal
The EMBO Journal 10.1038/s44318-024-00121-5DOI: 10.1038/s44318-024-00121-5
PMID: 38778155
PMCID:
Date of Paper: 22/05/2024
Division: Cell BiologyManolis D, Hasan S, Maraveyas A, O'Brien DP, Kessler BM, Kramer H, Nikitenko LL.
Quantitative proteomics reveals CLR interactome in primary human cells
Journal of Biological Chemistry 10.1016/j.jbc.2024.107399DOI: 10.1016/j.jbc.2024.107399
PMID: 38777147
PMCID:
Date of Paper: 20/05/2024
Division: Cell BiologyHale VL, Hooker J, Russo CJ, Löwe J.
Honeycomb gold specimen supports enabling orthogonal focussed ion beam-milling of elongated cells for cryo-ET
Journal of Structural Biology 10.1016/j.jsb.2024.108097DOI: 10.1016/j.jsb.2024.108097
PMID: 38772448
PMCID:
Date of Paper: 19/05/2024
Division: Structural StudiesQi C, Kobayashi R, Kawakatsu S, Kametani F, Scheres SHW, Goedert M, Hasegawa M.
Tau filaments with the chronic traumatic encephalopathy fold in a case of vacuolar tauopathy with VCP mutation D395G
Acta Neuropathologica 147(1):86DOI: 0.1007/s00401-024-02741-x
PMID: 38758288
PMCID:
Date of Paper: 17/05/2024
Division: Structural Studies, NeurobiologyHegde RS.
Getting membrane proteins into shape
Molecular Cell 84(10):1821-1823DOI: 10.1016/j.molcel.2024.04.024
PMID: 38759622
PMCID:
Date of Paper: 16/05/2024
Division: Cell BiologyCezanne A, Foo S, Kuo YW, Baum B.
The Archaeal Cell Cycle
Annual Review of Cell and Developmental Biology 10.1146/annurev-cellbio-111822-120242DOI: 10.1146/annurev-cellbio-111822-120242
PMID: 38748857
PMCID:
Date of Paper: 15/05/2024
Division: Cell BiologyEckstein N, Bates AS, Champion A, Du M, Yin Y, Schlegel P, Lu AK, Rymer T, Finley-May S, Paterson T, Parekh R, Dorkenwald S, Matsliah A, Yu SC, McKellar C, Sterling A, Eichler K, Costa M, Seung S, Murthy M, Hartenstein V, Jefferis GSXE, Funke J.
Neurotransmitter classification from electron microscopy images at synaptic sites in Drosophila melanogaster
Cell 187(10):2574-2594.e23DOI: 10.1016/j.cell.2024.03.016
PMID: 38729112
PMCID: PMC11106717
Date of Paper: 09/05/2024
Division: NeurobiologyUnwin N.
Influence of lipid bilayer on the structure of the muscle-type nicotinic acetylcholine receptor
Proceedings of the National Academy of Sciences of the United States of America 121(19):e2319913121DOI: 10.1073/pnas.2319913121
PMID: 38683987
PMCID: PMC11087746
Date of Paper: 07/05/2024
Division: Neurobiology