Thimaradka V., Hoon Oh J., Heroven C., Radu Aricescu A., Yuzaki M., Tamura T., Hamachi I.
Site-specific covalent labeling of His-tag fused proteins with N-acyl-N-alkyl sulfonamide reagent
Bioorganic & Medicinal Chemistry 30:115947DOI: 10.1016/j.bmc.2020.115947
PMID: 33360195
PMCID:
Date of Paper: 15/01/2021
Division: NeurobiologyBlum M., Chang H. Y., Chuguransky S., Grego T., Kandasaamy S., Mitchell A., Nuka G., Paysan-Lafosse T., Qureshi M., Raj S., Richardson L., Salazar G. A., Williams L., Bork P., Bridge A., Gough J., Haft D. H., Letunic I., Marchler-Bauer A., Mi H., Natale D. A., Necci M., Orengo C. A., Pandurangan A. P., Rivoire C., Sigrist C. J. A., Sillitoe I., Thanki N., Thomas P. D., Tosatto S. C. E., Wu C. H., Bateman A., Finn R. D.
The InterPro protein families and domains database: 20 years on
Nucleic Acids Research 49(D1):D344-D354. 8 January 2021DOI: 10.1093/nar/gkaa977
PMID: 33156333
PMCID: PMC7778928
Date of Paper: 08/01/2021
Division: Structural Studies
Download pdfValdes-Aleman J., Fetter R. D., Sales E. C., Heckman E. L., Venkatasubramanian L., Doe C. Q., Landgraf M., Cardona A., Zlatic M.
Comparative Connectomics Reveals How Partner Identity, Location, and Activity Specify Synaptic Connectivity in Drosophila
Neuron 109(1):105-122.e7DOI: 10.1016/j.neuron.2020.10.004
PMID: 33120017
PMCID:
Date of Paper: 06/01/2021
Division: NeurobiologyWu L. F., Liu Z., Sutherland J. D.
pH-Dependent peptide bond formation by the selective coupling of α-amino acids in water
Chemical Communications 57(1):73-76. January 2021DOI: 10.1039/d0cc06042a
PMID: 33242043
PMCID:
Date of Paper: 05/01/2021
Division: Protein & Nucleic Acid ChemistryFocht D., Neumann C., Lyons J., Eguskiza Bilbao A., Blunck R., Malinauskaite L., Schwarz I. O., Javitch J. A., Quick M., Nissen P.
A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition
EMBO Journal 40(1):e105164. 4 January 2021DOI: 10.15252/embj.2020105164
PMID: 33155685
PMCID:
Date of Paper: 04/01/2021
Division: NeurobiologyPanova V., Gogoi M., Rodriguez-Rodriguez N., Sivasubramaniam M., Jolin H. E., Heycock M. W. D., Walker J. A., Rana B. M. J., Drynan L. F., Hodskinson M., Pannell R., King G., Wing M., Easton A. J., Oedekoven C. A., Kent D. G., Fallon P. G., Barlow J. L., McKenzie A. N. J.
Group-2 innate lymphoid cell-dependent regulation of tissue neutrophil migration by alternatively activated macrophage-secreted Ear11
Mucosal Immunology 14(1):26-37. January 2021DOI: 10.1038/s41385-020-0298-2
PMID: 32457448
PMCID: PMC7790759
Date of Paper: 01/01/2021
Division: Protein & Nucleic Acid Chemistry
Download pdfSpagnol V., Oliveira C. A. B., Randle S. J., Passos P. M. S, Correia C. R. S. T. B., Simaroli N. B., Oliveira J. S., Mevissen T. E. T., Medeiros A. C., Gomes M. D., Komander D., Laman H., Teixeira F. R.
The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway
Biochimica et Biophysica acta. General Subjects 1865(1):129754DOI: 10.1016/j.bbagen.2020.129754
PMID: 33010352
PMCID:
Date of Paper: 01/01/2021
Division: Protein & Nucleic Acid ChemistryFrechard A., Sharov G., Werderer M., Schultz P.
Optimization of Sample Preparation for the Observation of Macromolecular Complexes by Electron (cryo-)Microscopy
Methods in Molecular Biology 2247:243-256DOI: 10.1007/978-1-0716-1126-5_13
PMID: 33301121
PMCID:
Date of Paper: 01/01/2021
Division: Structural StudiesNagai J., Yu X., Papouin T., Cheong E., Freeman M. R., Monk K. R., Hastings M. H., Haydon P. G., Rowitch D., Shaham S., Khakh B. S.
Behaviorally consequential astrocytic regulation of neural circuits
Neuron e-pub: published online 31 December 2020DOI: 10.1016/j.neuron.2020.12.008
PMID: 33385325
PMCID:
Date of Paper: 31/12/2020
Division: NeurobiologyScherer K. M., Manton J. D., Soh T. K., Mascheroni L., Connor V., Crump C. M., Kaminski C. F.
A fluorescent reporter system enables spatiotemporal analysis of host cell modification during herpes simplex virus-1 replication
Journal of Biological Chemistry e-pub: published online 30 December 2020DOI: 10.1074/jbc.ra120.016571
PMID: 33380421
PMCID:
Date of Paper: 30/12/2020
Division: Cell BiologyHarris L. D., Le Pen J., Scholz N., Mieszczanek J., Vaughan N., Davis S., Berridge G., Kessler B., Bienz M., Licchesi J. D. F.
The deubiquitinase TRABID stabilises the K29/K48-specific E3 ubiquitin ligase HECTD1
Journal of Biological Chemistry e-pub: published online 30 December 2020DOI: 10.1074/jbc.ra120.015162
PMID: 33380427
PMCID:
Date of Paper: 30/12/2020
Division: Protein & Nucleic Acid ChemistryBonfio C.
The curious case of peptide-coordinated iron-sulfur clusters: prebiotic and biomimetic insights
Dalton Transactions e-pub: published online 22 December 2020DOI: 10.1039/d0dt03947k
PMID: 33351009
PMCID:
Date of Paper: 22/12/2020
Division: Protein & Nucleic Acid ChemistryLehmann L. C., Bacic L., Hewitt G., Brackmann K., Sabantsev A., Gaullier G., Pytharopoulou S., Degliesposti G., Okkenhaug H., Tan S., Costa A., Skehel J. M., Boulton S. J., Deindl S.
Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch
Cell Reports 33(12):108529. 22 December 2020DOI: 10.1016/j.celrep.2020.108529
PMID: 33357431
PMCID:
Date of Paper: 22/12/2020
Division: Cell BiologyÖzbey N. P., Imanikia S., Krueger C., Hardege I., Morud J., Sheng M., Schafer W. R., Casanueva M. O., Taylor R. C.
Tyramine Acts Downstream of Neuronal XBP-1s to Coordinate Inter-tissue UPRER Activation and Behavior in C. elegans
Developmental Cell 55(6):754-770.e6. 21 December 2020DOI: 10.1016/j.devcel.2020.10.024
PMID: 33232669
PMCID: PMC7758879
Date of Paper: 21/12/2020
Division: Neurobiology
Download pdfCanton J., Blees H., Henry C. M., Buck M. D., Schulz O., Rogers N. C., Childs E., Zelenay S., Rhys H., Domart M. C., Collinson L., Alloatti A., Ellison C. J., Amigorena S., Papayannopoulos V., Thomas D. C., Randow F., Reis E Sousa C.
The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens
Nature Immunology e-pub: published online 21 December 2020DOI: 10.1038/s41590-020-00824-x
PMID: 33349708
PMCID:
Date of Paper: 21/12/2020
Division: Protein & Nucleic Acid ChemistryKe Z., Oton J., Qu K., Cortese M., Zila V., McKeane L., Nakane T., Zivanov J., Neufeldt C. J., Cerikan B., Lu J. M., Peukes J., Xiong X., Kräusslich H. G., Scheres S. H. W., Bartenschlager R., Briggs J. A. G.
Structures and distributions of SARS-CoV-2 spike proteins on intact virions
Nature 588(7838):498-502. 17 December 2020DOI: 10.1038/s41586-020-2665-2
PMID: 32805734
PMCID: PMC7116492
Date of Paper: 17/12/2020
Division: Structural Studies
Download pdfDingler F. A., Wang M., Mu A., Millington C. L., Oberbeck N., Watcham S., Pontel L. B., Kamimae-Lanning A. N., Langevin F., Nadler C., Cordell R. L., Monks P. S., Yu R., Wilson N. K., Hira A., Yoshida K., Mori M., Okamoto Y., Okuno Y., Muramatsu H., Shiraishi Y., Kobayashi M., Moriguchi T., Osumi T., Kato M., Miyano S., Ito E., Kojima S., Yabe H., Yabe M., Matsuo K., Ogawa S., Göttgens B., Hodskinson M. R. G, Takata M., Patel K. J.
Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans
Molecular Cell 80(6):996-1012.e9. 17 December 2020DOI: 10.1016/j.molcel.2020.10.012
PMID: 33147438
PMCID: PMC7758861
Date of Paper: 17/12/2020
Division: Protein & Nucleic Acid ChemistryGiandomenico S. L., Sutcliffe M., Lancaster M. A.
Generation and long-term culture of advanced cerebral organoids for studying later stages of neural development
Nature Protocols e-pub: published online 16 December 2020DOI: 10.1038/s41596-020-00433-w
PMID: 33328611
PMCID:
Date of Paper: 16/12/2020
Division: Cell BiologyFerus M., Rimmer P., Cassone G., Knížek A., Civiš S., Šponer J. E., Ivanek O., Šponer J., Saeidfirozeh H., Kubelík P., Dudžák R., Petera L., Juha L., Pastorek A., Křivková A., Krůs M.
One-Pot Hydrogen Cyanide-Based Prebiotic Synthesis of Canonical Nucleobases and Glycine Initiated by High-Velocity Impacts on Early Earth
Astrobiology 20(12):1476-1488. 14 December 2020DOI: 10.1089/ast.2020.2231
PMID: 32955922
PMCID:
Date of Paper: 14/12/2020
Division: Protein & Nucleic Acid ChemistryLi F., Lindsey J. W., Marin E. C., Otto N., Dreher M., Dempsey G., Stark I., Bates A. S., Pleijzier M. W., Schlegel P., Nern A., Takemura S. Y., Eckstein N., Yang T., Francis A., Braun A., Parekh R., Costa M., Scheffer L. K., Aso Y., Jefferis G. S., Abbott L. F., Litwin-Kumar A., Waddell S., Rubin G. M.
The connectome of the adult Drosophila mushroom body provides insights into function
Elife e-pub: published online 14 December 2020DOI: 10.7554/elife.62576
PMID: 33315010
PMCID:
Date of Paper: 14/12/2020
Division: Neurobiologyde la Torre D., Chin J. W.
Reprogramming the genetic code
Nature reviews. Genetics e-pub: published online 14 December 2020DOI: 10.1038/s41576-020-00307-7
PMID: 33318706
PMCID:
Date of Paper: 14/12/2020
Division: Protein & Nucleic Acid ChemistrySamson C., Legrand P., Tekpinar M., Rozenski J., Abramov M., Holliger P., Pinheiro V. B., Herdwijn P., Delarue M.
Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution
Biomolecules 10(12):1647. 8 December 2020DOI: 10.3390/biom10121647
PMID: 33302546
PMCID: PMC7763228
Date of Paper: 08/12/2020
Division: Protein & Nucleic Acid Chemistry
Download pdfKube M., Kohler F., Feigl E., Nagel-Yüksel B., Willner E. M., Funke J. J., Gerling T., Stömmer P., Honemann M. N., Martin T. G., Scheres S. H. W., Dietz H.
Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution
Nature Communications 11(1):6229. December 2020DOI: 10.1038/s41467-020-20020-7
PMID: 33277481
PMCID: PMC7718922
Date of Paper: 04/12/2020
Division: Structural Studies
Download pdfPellegrini L., Albecka A., Mallery D. L., Kellner M. J., Paul D., Carter A. P., James L. C., Lancaster M. A.
SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids
Cell Stem Cell 27(6):951-961.e5. 3 December 2020DOI: 10.1016/j.stem.2020.10.001
PMID: 33113348
PMCID: PMC7553118
Date of Paper: 03/12/2020
Division: Structural Studies, Protein & Nucleic Acid Chemistry, Cell Biology
Download pdfMartin-Cofreces N. B., Chichon F. J., Calvo E., Torralba D., Bustos-Moran E., Dosil S. G., Rojas-Gomez A., Bonzon-Kulichenko E., Lopez J. A., Otón J., Sorrentino A., Zabala J. C., Vernos I., Vazquez J., Valpuesta J. M., Sanchez-Madrid F.
The chaperonin CCT controls T cell receptor-driven 3D configuration of centrioles
Science Advances 6(49):eabb7242. 2 December 2020DOI: 10.1126/sciadv.abb7242
PMID: 33268369
PMCID:
Date of Paper: 02/12/2020
Division: Structural Studies
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