Peet M. J., Henderson R., Russo C. J.
The energy dependence of contrast and damage in electron cryomicroscopy of biological molecules
Ultramicroscopy 203:125-131. August 2019DOI: 10.1016/j.ultramic.2019.02.007
PMID: 30773415
PMCID:
Date of Paper: 01/08/2019
Division: Structural Studies
Download pdfGattkowski E., Johnsen A., Bauche A., Möckl F., Kulow F., Garcia Alai M., Rutherford T. J., Fliegert R., Tidow H.
Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2
Biochimica et Biophysica Acta. Molecular Cell Research 1866(7):1162-1170. July 2019DOI: 10.1016/j.bbamcr.2018.12.010
PMID: 30584900
PMCID:
Date of Paper: 01/07/2019
Division: Structural StudiesMalcolm J. C., Breuillaud L., Do Carmo S., Hall H., Welikovitch L. A., Macdonald J. A., Goedert M., Cuello A. C.
Neuropathological changes and cognitive deficits in rats transgenic for human mutant tau recapitulate human tauopathy
Neurobiology of Disease 127:323-338. July 2019DOI: 10.1016/j.nbd.2019.03.018
PMID: 30905766
PMCID:
Date of Paper: 01/07/2019
Division: NeurobiologyBates A. S., Janssens J., Jefferis G. S., Aerts S.
Neuronal cell types in the fly: single-cell anatomy meets single-cell genomics
Current Opinion in Neurobiology 56:125-134. June 2019DOI: 10.1016/j.conb.2018.12.012
PMID: 30703584
PMCID:
Date of Paper: 01/06/2019
Division: NeurobiologyChitwood P. J., Hegde R. S.
The Role of EMC during Membrane Protein Biogenesis
Trends in Cell Biology 29(5):371-384. May 2019DOI: 10.1016/j.tcb.2019.01.007
PMID: 30826214
PMCID:
Date of Paper: 01/05/2019
Division: Cell BiologyBottermann M., Foss S., Caddy S. L., Clift D., van Tienen L. M., Vaysburd M., Cruickshank J., O'Connell K., Clark J., Mayes K., Higginson K., Lode H. E., McAdam M. B., Sandlie I., Andersen J. T., James L. C.
Complement C4 Prevents Viral Infection through Capsid Inactivation
Cell Host & Microbe 25(4):617-629.e7. 10 April 2019DOI: 10.1016/j.chom.2019.02.016
PMID: 30926239
PMCID:
Date of Paper: 10/04/2019
Division: Protein & Nucleic Acid Chemistry
Download pdfMohiuddin M., Rahman M. M., Sale J. E., Pearson C. E.
CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs
Nucleic Acids Research 47(6):2966-2980. 8 April 2019DOI: 10.1093/nar/gkz009
PMID: 30657944
PMCID: PMC6451104
Date of Paper: 08/04/2019
Division: Protein & Nucleic Acid Chemistry
Download pdfAnderson A., Chew Y. L., Schafer W., McMullan R.
Identification of a conserved, orphan G-protein coupled receptor required for efficient pathogen clearance in C. elegans
Infection and Immunity 87(4). April 2019DOI: 10.1128/IAI.00034-19
PMID: 30692178
PMCID:
Date of Paper: 01/04/2019
Division: NeurobiologyLiu Z., Ajram G., Rossi J. C., Pascal R.
The Chemical Likelihood of Ribonucleotide-α-Amino acid Copolymers as Players for Early Stages of Evolution
Journal of Molecular Evolution 87(2-3):83-92. April 2019DOI: 10.1007/s00239-019-9887-7
PMID: 30788531
PMCID: PMC6443614
Date of Paper: 01/04/2019
Division: Protein & Nucleic Acid Chemistry
Download pdfGangadhara G., Dahl G., Bohnacker T., Rae R., Gunnarsson J., Blaho S., Öster L., Lindmark H., Karabelas K., Pemberton N., Tyrchan C., Mogemark M., Wymann M. P., Williams R. L., Perry M. W. D., Papavoine T., Petersen J.
A class of highly selective inhibitors bind to an active state of PI3Kγ
Nature Chemical Biology 15(4):348-357. April 2019DOI: 10.1038/s41589-018-0215-0
PMID: 30718815
PMCID:
Date of Paper: 01/04/2019
Division: Protein & Nucleic Acid ChemistryBeale A. D., Kruchek E., Kitcatt S. J., Henslee E. A., Parry J. S. W., Braun G., Jabr R., von Schantz M., O'Neill J. S., Labeed F. H.
Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells
Journal of Biological Rhythms 34(2):144-153. April 2019DOI: 10.1177/0748730419836370
PMID: 30898060
PMCID:
Date of Paper: 01/04/2019
Division: Cell BiologyGiandomenico S. L., Mierau S. B., Gibbons G. M., Wenger L. M. D., Masullo L., Sit T., Sutcliffe M., Boulanger J., Tripodi M., Derivery E., Paulsen O., Lakatos A., Lancaster M. A.
Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output
Nature Neuroscience 22(4):669-679. April 2019DOI: 10.1038/s41593-019-0350-2
PMID: 30886407
PMCID:
Date of Paper: 01/04/2019
Division: Cell Biology, NeurobiologyAspuru-Guzik A., Baik M. H., Balasubramanian S., Banerjee R., Bart S., Borduas-Dedekind N., Chang S., Chen P., Corminboeuf C., Coudert F. X., Cronin L., Crudden C., Cuk T., Doyle A. G., Fan C., Feng X., Freedman D., Furukawa S., Ghosh S., Glorius F., Jeffries-El M., Katsonis N., Li A., Linse S. S., Marchesan S., Maulide N., Milo A., Narayan A. R. H., Naumov P., Nevado C., Nyokong T., Palacin ., Reid M., Robinson C., Robinson G., Sarpong R., Schindler C., Schlau-Cohen G. S., Schmidt T. W., Sessoli R., Shao-Horn Y., Sleiman H., Sutherland J., Taylor A., Tezcan A., Tortosa M., Walsh A., Watson A. J. B., Weckhuysen B. M., Weiss E., Wilson D., Yam V. W., Yang X., Ying J. Y., Yoon T., You S. L., Zarbin A. J. G ., Zhang H.
Charting a course for chemistry
Nature Chemistry 11(4):286-294. April 2019DOI: 10.1038/s41557-019-0236-7
PMID: 30903035
PMCID:
Date of Paper: 01/04/2019
Division: Protein & Nucleic Acid ChemistryGersch M., Wagstaff J. L., Toms A. V., Graves B., Freund S. M. V., Komander D.
Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity
Molecular Cell e-pub: published online 26 March 2019DOI: 10.1016/j.molcel.2019.02.030
PMID: 30926242
PMCID:
Date of Paper: 26/03/2019
Division: Protein & Nucleic Acid Chemistry
Download pdfHill C. H., Boreikaitė V., Kumar A., Casañal A., Kubík P., Degliesposti G., Maslen S., Mariani A., von Loeffelholz O., Girbig M., Skehel M, Passmore L. A.
Activation of the Endonuclease that Defines mRNA 3' Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex
Molecular Cell 73(6):1217-1231.e11. 21 March 2019DOI: 10.1016/j.molcel.2018.12.023
PMID: 30737185
PMCID: PMC6436931
Date of Paper: 21/03/2019
Division: Structural Studies
Download pdfFalcon B., Zivanov J., Zhang W., Murzin A. G., Garringer H. J., Vidal R., Crowther R. A., Newell K. L., Ghetti B., Goedert M., Scheres S. H. W.
Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules
Nature e-pub: published online 20 March 2019DOI: 10.1038/s41586-019-1026-5
PMID: 30894745
PMCID:
Date of Paper: 20/03/2019
Division: Neurobiology, Structural StudiesColin-York H., Javanmardi Y., Skamrahl M., Kumari S., Chang V. T., Khuon S., Taylor A., Chew T. L., Betzig E., Moeendarbary E., Cerundolo V., Eggeling C., Fritzsche M..
Cytoskeletal Control of Antigen-Dependent T Cell Activation
Cell Reports 26(12):3369-3379.e5. 19 March 2019DOI: 10.1016/j.celrep.2019.02.074
PMID: 30893608
PMCID: PMC6426652
Date of Paper: 19/03/2019
Division: Neurobiology
Download pdfShapson-Coe A., Valeiras B., Wall C., Rada C.
Aicardi-Goutières Syndrome associated mutations of RNase H2B impair its interaction with ZMYM3 and the CoREST histone-modifying complex
PloS one 14(3):e0213553. 19 March 2019DOI: 10.1371/journal.pone.0213553
PMID: 30889214
PMCID: PMC6424451
Date of Paper: 19/03/2019
Division: Protein & Nucleic Acid Chemistry
Download pdfGoedert M., Falcon B., Zhang W., Ghetti B., Scheres S. H. W.
Distinct Conformers of Assembled Tau in Alzheimer's and Pick's Diseases
Cold Spring Harbor Symposia on Quantitative Biology e-pub: published online 18 March 2019DOI: 10.1101/sqb.2018.83.037580
PMID: 30886056
PMCID:
Date of Paper: 18/03/2019
Division: Neurobiology, Structural StudiesMacdonald J. A., Bronner I. F., Drynan L., Fan J., Curry A., Fraser G., Lavenir I., Goedert M.
Assembly of transgenic human P301S Tau is necessary for neurodegeneration in murine spinal cord
Acta Neuropathologica Communications 7(1):44. 18 March 2019DOI: 10.1186/s40478-019-0695-5
PMID: 30885267
PMCID: PMC6421678
Date of Paper: 18/03/2019
Division: Neurobiology
Download pdfTaylor M. R. G., Yeeles J. T. P.
Dynamics of Replication Fork Progression Following Helicase-Polymerase Uncoupling in Eukaryotes
Journal of Molecular Biology e-pub: published online 17 March 2019DOI: 10.1016/j.jmb.2019.03.011
PMID: 30894292
PMCID:
Date of Paper: 17/03/2019
Division: Protein & Nucleic Acid ChemistryHerguedas B., Watson J. F., Ho H, Cais O., García-Nafría J., Greger I. H.
Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8
Science e-pub: published online 14 March 2019DOI: 10.1126/science.aav9011
PMID: 30872532
PMCID:
Date of Paper: 14/03/2019
Division: Neurobiology, Structural StudiesWu R. A., Semlow D. R., Kamimae-Lanning A. N., Kochenova O. V., Chistol G., Hodskinson M. R., Amunugama R., Sparks J. L., Wang M., Deng L., Mimoso C. A., Low E., Patel K. J., Walter J. C. 7.
TRAIP is a master regulator of DNA interstrand crosslink repair
Nature 567(7747):267-272. 14 March 2019DOI: 10.1038/s41586-019-1002-0
PMID: 30842657
PMCID:
Date of Paper: 14/03/2019
Division: Protein & Nucleic Acid ChemistryInglis A. J., Masson G. R., Shao S., Perisic O., McLaughlin S. H., Hegde R. S., Williams R. L.
Activation of GCN2 by the ribosomal P-stalk
Proceedings of the National Academy of Sciences of the United States of America 116(11):4946-4954. 12 March 2019DOI: 10.1073/pnas.1813352116
PMID: 30804176
PMCID: PMC6421407
Date of Paper: 12/03/2019
Division: Cell Biology, Protein & Nucleic Acid Chemistry
Download pdfRavenhill B. J., Boyle K. B., von Muhlinen N., Ellison C. J., Masson G. R., Otten E. G., Foeglein A., Williams R., Randow F.
The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria
Molecular Cell e-pub: published online 7 March 2019DOI: 10.1016/j.molcel.2019.01.041
PMID: 30853402
PMCID:
Date of Paper: 07/03/2019
Division: Protein & Nucleic Acid Chemistry
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