Tsuchiya Y., Byrne D. P., Burgess S. G., Bormann J., Baković J., Huang Y., Zhyvoloup A., Yu B. Y. K., Peak-Chew S., Tran T., Bellany F., Tabor A. B., Chan A. E., Guruprasad L., Garifulin O., Filonenko V., Vonderach M., Ferries S., Eyers C. E., Carroll J., Skehel M., Bayliss R., Eyers P. A., Gout I.
Covalent Aurora A regulation by the metabolic integrator coenzyme A
Redox Biology 28:101318. January 2020DOI: 10.1016/j.redox.2019.101318
PMID: 31546169
PMCID:
Date of Paper: 01/01/2020
Division: Cell BiologyKumar A., Clerici M., Muckenfuss L. M., Passmore L. A., Jinek M.
Mechanistic insights into mRNA 3'-end processing
Current Opinion in Structural Biology 59:143-150. December 2019DOI: 10.1016/j.sbi.2019.08.001
PMID: 31499460
PMCID:
Date of Paper: 01/12/2019
Division: Structural Studies
Download pdfBaković J., Yu B. Y. K., Silva D., Chew S. P., Kim S., Ahn S. H., Palmer L., Aloum L., Stanzani G., Malanchuk O., Duchen M. R., Singer M., Filonenko V., Lee T. H., Skehel M., Gout I.
A key metabolic integrator, coenzyme A, modulates the activity of peroxiredoxin 5 via covalent modification
Molecular and Cellular Biochemistry 461(1-2):91-102. November 2019DOI: 10.1007/s11010-019-03593-w
PMID: 31375973
PMCID:
Date of Paper: 01/11/2019
Division: Cell BiologyShakeel S., Rajendra E., Alcón P., O'Reilly F., Chorev D. S., Maslen S., Degliesposti G., Russo C. J., He S., Hill C. H., Skehel J. M., , Rappsilber J., Robinson C. V., Passmore L. A.
Structure of the Fanconi anaemia monoubiquitin ligase complex
Nature e-pub: published online 30 October 2019DOI: 10.1038/s41586-019-1703-4
PMID: 31666700
PMCID:
Date of Paper: 30/10/2019
Division: Protein & Nucleic Acid Chemistry, Structural StudiesAhmad J., Khubaib M., Sheikh J. A., Pancsa R., Kumar S., Srinivasan A., Babu M. M., Hasnain S. E., Ehtesham N. Z.
Disorder-to-order transition in PE-PPE proteins of Mycobacterium tuberculosis augments the pro-pathogen immune response
FEBS Open bio e-pub: published online 23 October 2019DOI: 10.1002/2211-5463.12749
PMID: 31643141
PMCID:
Date of Paper: 23/10/2019
Division: Structural StudiesMasson G. R., Williams R. L.
Structural Mechanisms of PTEN Regulation
Cold Spring Harbor Perspectives in Medicine e-pub: published online 21 October 2019DOI: 10.1101/cshperspect.a036152
PMID: 31636093
PMCID:
Date of Paper: 21/10/2019
Division: Protein & Nucleic Acid ChemistryZeng J., Slodkowicz G., James L. C.
Rare missense variants in the human cytosolic antibody receptor preserve antiviral function
ELife 8: e48339. 15 October 2019DOI: 10.7554/eLife.48339
PMID: 31613747
PMCID: PMC6794091
Date of Paper: 15/10/2019
Division: Protein & Nucleic Acid Chemistry
Download pdfPolyansky A. A., Kreuter M., Sutherland J. D., Zagrovic B.
Direct interplay between stereochemistry and conformational preferences in aminoacylated oligoribonucleotides
Nucleic Acids Research e-pub: published online 15 October 2019DOI: 10.1093/nar/gkz902
PMID: 31612955
PMCID:
Date of Paper: 15/10/2019
Division: Protein & Nucleic Acid ChemistryMasson G. R.
Towards a model of GCN2 activation
Biochemical Society Transactions 47(5):1481-1488. October 2019DOI: 10.1042/BST20190331
PMID: 31647517
PMCID:
Date of Paper: 11/10/2019
Division: Protein & Nucleic Acid ChemistryAnandapadamanaban M., Masson G. R., Perisic O., Berndt A., Kaufman J., Johnson C. M., Santhanam B., Rogala K. B., Sabatini D. M., Williams R. L.
Architecture of human Rag GTPase heterodimers and their complex with mTORC1
Science 366(6462):203-210. 11 October 2019DOI: 10.1126/science.aax3939
PMID: 31601764
PMCID:
Date of Paper: 11/10/2019
Division: Protein & Nucleic Acid ChemistryWu C., Travers A.
Modelling and DNA topology of compact 2-start and 1-start chromatin fibres
Nucleic Acids Research 47(18):9902-9924. 10 October 2019DOI: 10.1093/nar/gkz495
PMID: 31219588
PMCID: PMC6765122
Date of Paper: 10/10/2019
Division: Cell Biology
Download pdfYan K., Yang J., Zhang Z., McLaughlin S. H., Chang L., Fasci D., Ehrenhofer-Murray A. E., Heck A. J. R., Barford D.
Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome
Nature 574:278-282. 10 October 2019DOI: 10.1038/s41586-019-1609-1
PMID: 31578520
PMCID:
Date of Paper: 10/10/2019
Division: Structural StudiesFamelis N., Rivera-Calzada A., Degliesposti G., Wingender M., Mietrach N., Skehel J. M., Fernandez-Leiro R., Böttcher B., Schlosser A., Llorca O., Geibel S.
Architecture of the mycobacterial type VII secretion system
Nature e-pub: published online 9 October 2019DOI: 10.1038/s41586-019-1633-1
PMID: 31597161
PMCID:
Date of Paper: 09/10/2019
Division: Cell BiologyWinter G.
Harnessing Evolution to Make Medicines (Nobel Lecture)
Angewandte Chemie 58(41):14438-14445. 7 October 2019DOI: 10.1002/anie.201909343
PMID: 31529671
PMCID:
Date of Paper: 07/10/2019
Division: Protein & Nucleic Acid ChemistryDas S., Malaby A. W., Nawrotek A., Zhang W., Zeghouf M., Maslen S., Skehel M., Chakravarthy S., Irving T. C., Bilsel O., Cherfils J., Lambright D. G.
Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes
Structure e-pub: published online 7 October 2019DOI: 10.1016/j.str.2019.09.007
PMID: 31601460
PMCID:
Date of Paper: 07/10/2019
Division: Cell BiologyMasullo L., Tripodi M.
Goal-Oriented Behaviour: The Ventral Tegmental Area in Motivated Movements
Current Biology 29(19):R922-R925. 7 October 2019DOI: 10.1016/j.cub.2019.08.041
PMID: 31593666
PMCID:
Date of Paper: 07/10/2019
Division: NeurobiologyToste Rêgo A., da Fonseca P. C. A.
Characterization of Fully Recombinant Human 20S and 20S-PA200 Proteasome Complexes
Molecular Cell 76(1):138-147.e5. 3 October 2019DOI: 10.1016/j.molcel.2019.07.014
PMID: 31473102
PMCID:
Date of Paper: 03/10/2019
Division: Structural Studies
Download pdfKiss L., Zeng J., Dickson C. F., Mallery D. L., Yang J. C., McLaughlin S. H., Boland A., Neuhaus D., James L. C.
A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases
Nature Communications 10(1):4502. 3 October 2019DOI: 10.1038/s41467-019-12388-y
PMID: 31582740
PMCID: PMC6776665
Date of Paper: 03/10/2019
Division: Protein & Nucleic Acid Chemistry, Structural Studies
Download pdfGam R., Sung M., Prasad Pandurangan A.
Experimental and Computational Approaches to Direct Cell Reprogramming: Recent Advancement and Future Challenges
Cells 8(10). 2 October 2019DOI: 10.3390/cells8101189
PMID: 31581647
PMCID:
Date of Paper: 02/10/2019
Division: Structural StudiesCasañal A., Shakeel S., Passmore L. A.
Interpretation of medium resolution cryoEM maps of multi-protein complexes
Current Opinion in Structural Biology 58:166-174. October 2019DOI: 10.1016/j.sbi.2019.06.009
PMID: 31362190
PMCID:
Date of Paper: 01/10/2019
Division: Structural Studies, Cell Biology
Download pdfGonzález-Rueda A., Tripodi M.
Éloge de la Fuite: Neural Circuits for Avoiding Dangerous Situations
Trends in Neurosciences 42(10):657-659. October 2019DOI: 10.1016/j.tins.2019.07.006
PMID: 31399288
PMCID:
Date of Paper: 01/10/2019
Division: NeurobiologyBauer M. R., Jones R. N., Tareque R. K., Springett B., Dingler F. A., Verduci L., Patel K. J., Fersht A. R., Joerger A. C., Spencer J.
A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C
Future Medicinal Chemistry 11(19):2491-2504. October 2019DOI: 10.4155/fmc-2019-0181
PMID: 31633398
PMCID: PMC6803818
Date of Paper: 01/10/2019
Division: Protein & Nucleic Acid Chemistry
Download pdfMaluenda D., Majtner T., Horvath P., Vilas J. L., Jiménez-Moreno A., Mota J., Ramírez-Aportela E., Sánchez-García R., Conesa P., Del Caño L., Rancel Y., Fonseca Y., Martínez M., Sharov G., García C. A., Strelak D., Melero R., Marabini R., Carazo J. M., Sorzano C. O. S.
Flexible workflows for on-the-fly electron-microscopy single-particle image processing using Scipion
Acta Crystallographica. Section D, Structural Biology 75(Pt 10):882-894.1 October 2019DOI: 10.1107/S2059798319011860
PMID: 31588920
PMCID: PMC6778851
Date of Paper: 01/10/2019
Division: Structural Studies
Download pdfDhillon P., Winter G.
In conversation with Greg Winter
FEBS Journal 286(19):3742-3744. October 2019DOI: 10.1111/febs.15064
PMID: 31588669
PMCID:
Date of Paper: 01/10/2019
Division: Protein & Nucleic Acid ChemistryKlein A. F., Varela M. A., Arandel L., Holland A., Naouar N., Arzumanov A., Seoane D., Revillod L., Bassez G., Ferry A., Jauvin D., Gourdon G., Puymirat J., Gait M. J., Furling D., Wood M. J.
Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice
The Journal of Clinical Investigation e-pub: published online 30 September 2019DOI: 10.1172/JCI128205
PMID: 31479430
PMCID:
Date of Paper: 30/09/2019
Division: Protein & Nucleic Acid Chemistry