Li Y., McGrail D. J., Latysheva N., Yi S., Babu M. M., Sahni N.
Pathway perturbations in signaling networks: linking genotype to phenotype
Seminars in Cell & Developmental Biology e-pub: published online 10 May 2018DOI: 10.1016/j.semcdb.2018.05.001
PMID: 29738884
PMCID:
Date of Paper: 10/05/2018
Division: Structural StudiesGarcía-Nafría J., Lee Y., Bai X., Carpenter B., Tate C. G.
Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein
ELife 7, 4 May 2018DOI: 10.7554/eLife.35946
PMID: 29726815
PMCID:
Date of Paper: 04/05/2018
Division: Structural StudiesWalter L. M., Deguise M. O., Meijboom K. E., Betts C. A., Ahlskog N., van Westering T. L. E., Hazell G., McFall E., Kordala A., Hammond S. M., Abendroth F., Murray L. M., Shorrock H. K., Prosdocimo D. A., Haldar S.M., Jain M. K., Gillingwater T. H., Claus P., Kothary R., Wood M. J. A., Bowerman M.
Interventions targeting glucocorticoid-Krüppel-like factor 15-branched-chain amino acid signaling improve disease phenotypes in spinal muscular atrophy mice
EBioMedicine e-pub: published online 4 May 2018DOI: 10.1016/j.ebiom.2018.04.024
PMID: 29735415
PMCID:
Date of Paper: 04/05/2018
Division: Protein & Nucleic Acid ChemistryLancaster M. A.
Crinkle-cut brain organoids
Cell Stem Cell 22(5):616-618. 1 May 2018DOI: 10.1016/j.stem.2018.04.011
PMID: 29727676
PMCID:
Date of Paper: 01/05/2018
Division: Cell BiologyLancaster M. A.
Brain organoids get vascularized
Nature Biotechnology 36(5):407-408. 1 May 2018DOI: 10.1038/nbt.4133
PMID: 29734310
PMCID:
Date of Paper: 01/05/2018
Division: Cell BiologyLiu Y., Gupta G. D., Barnabas D. D., Agircan F.G., Mehmood S., Wu D., Coyaud E., Johnson C. M., McLaughlin S. H., Andreeva A., Freund S. M. V., Robinson C. V., Cheung S. W. T., Raught B., Pelletier L., van Breugel M.
Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly
Nature Communications 9(1):1731. 30 April 2018DOI: 10.1038/s41467-018-04122-x
PMID: 29712910
PMCID: PMC5928214
Date of Paper: 30/04/2018
Division: Structural Studies, Cell Biology
Download pdfStowell J. A. W., Wagstaff J. L., Hill C. H., Yu M., McLaughlin S. H., Freund S. M. V., Passmore L. A.
A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding
Journal of Biological Chemistry e-pub: published online 25 April 2018DOI: 10.1074/jbc.RA118.002291
PMID: 29695507
PMCID:
Date of Paper: 25/04/2018
Division: Structural Studies, Protein & Nucleic Acid Chemistry, Cell BiologyVagnoni A., Bullock S. L.
A cAMP/PKA/Kinesin-1 axis promotes the axonal transport of mitochondria in aging drosophila neurons
Current Biology 28(8):1265-1272.e4. 23 April 2018DOI: 10.1016/j.cub.2018.02.048
PMID: 29606421
PMCID: PMC5912900
Date of Paper: 23/04/2018
Division: Cell Biology
Download pdfBaud M. G. J., Bauer M. R., Verduci L., Dingler F. A., Patel K. J., Horil Roy D., Joerger A. C., Fersht A. R.
Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines
European Journal of Medicinal Chemistry 152:101-114. 21 April 2018DOI: 10.1016/j.ejmech.2018.04.035
PMID: 29702446
PMCID:
Date of Paper: 21/04/2018
Division: Protein & Nucleic Acid Chemistry, Cell Biology, Structural StudiesLando D., Basu S., Stevens T. J., Riddell A., Wohlfahrt K. J., Cao Y., Boucher W., Leeb M., Atkinson L. P., Lee S. F., Hendrich B., Klenerman D., Laue E. D.
Combining fluorescence imaging with Hi-C to study 3D genome architecture of the same single cell
Nature Protocols 13(5):1034-1061. 19 April 2018DOI: 10.1038/nprot.2018.017
PMID: 29674753
PMCID:
Date of Paper: 19/04/2018
Division: Cell BiologyReisinger S, N., Kong E., Molz B., Humberg T., Sideromenos S., Cicvaric A., Steinkellner T., Yang J, W., Cabatic M., Monje F. J., Sitte H. H., Nichols B. J., Pollak D. D.
Flotillin-1 interacts with the serotonin transporter and modulates chronic corticosterone response
Genes, Brain, and Behavior e12482. 18 April 2018DOI: 10.1111/gbb.12482
PMID: 29667320
PMCID:
Date of Paper: 18/04/2018
Division: Cell BiologyDickson C., Fletcher A. J., Vaysburd M., Yang J. C., Mallery D. L., Zeng J., Johnson C. M., McLaughlin S. H., Skehel M., Maslen S., Cruickshank J., Huguenin-Dezot N., Chin J. W., Neuhaus D., James L. C.
Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21
eLife 7. 18 April 2017DOI: 10.7554/eLife.32660
PMID: 29667579
PMCID: PMC5906095
Date of Paper: 18/04/2018
Division: Cell Biology, Protein & Nucleic Acid Chemistry, Structural Studies
Download pdfMartino F., Pal M., Muñoz-Hernández H., Rodríguez C. F., Núñez-Ramírez R., Gil-Carton D., Degliesposti G., Skehel J. M., Roe S. M., Prodromou C., Pearl L. H., Llorca O.
RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex
Nature Communications 9(1):1501. 16 April 2018DOI: 10.1038/s41467-018-03942-1
PMID: 29662061
PMCID: PMC5902453
Date of Paper: 16/04/2018
Division: Cell Biology
Download pdfReck-Peterson S. L., Redwine W. B., Vale R. D., Carter A. P.
The cytoplasmic dynein transport machinery and its many cargoes
Nature Reviews. Molecular Cell Biology e-pub: published online 16 April 2018DOI: 10.1038/s41580-018-0004-3
PMID: 29662141
PMCID:
Date of Paper: 16/04/2018
Division: Structural StudiesMeiser J., Schuster A., Pietzke M., Vande Voorde J., Athineos D., Oizel K., Burgos-Barragan G., Wit N., Dhayade S., Morton J. P., Dornier E., Sumpton D., Mackay G. M., Blyth K., Patel K. J., Niclou S. P., Vazquez A.
Increased formate overflow is a hallmark of oxidative cancer
Nature Communications 9(1):1368. 10 April 2018DOI: 10.1038/s41467-018-03777-w
PMID: 29636461
PMCID: PMC5893600
Date of Paper: 10/04/2018
Division: Protein & Nucleic Acid Chemistry
Download pdfBharat T. A. M., Hoffmann P. C., Kukulski W.
Correlative microscopy of vitreous sections provides insights into BAR-domain organization In situ
Structure e-pub: published online 10 April 2018DOI: 10.1016/j.str.2018.03.015
PMID: 29681471
PMCID:
Date of Paper: 10/04/2018
Division: Cell Biology, Structural StudiesRanjan S., Todd Z. R., Sutherland J. D., Sasselov D. D.
Sulfidic anion concentrations on early Earth for surficial origins-of-Life chemistry
Astrobiology e-pub: published online 8 April 2018DOI: 10.1089/ast.2017.1770
PMID: 29627997
PMCID:
Date of Paper: 08/04/2018
Division: Protein & Nucleic Acid ChemistryTsuchiya Y., Zhyvoloup A., Bakovic J., Thomas N., Yi Kun Yu B., Das S., Orengo C., Newell C., Ward J., Saladino G., Comitani F., Gervasio F. L., Malanchuk O. M., Khoruzhenko A. I., Filonenko V., Peak-Chew S. Y., Skehel M., Gout I..
Protein CoAlation and antioxidant function of Coenzyme A in prokaryotic cells
Biochemical Journal e-pub: published online 6 April 2018DOI: 10.1042/BCJ20180043
PMID: 29626155
PMCID:
Date of Paper: 06/04/2018
Division: Cell BiologyBertolotti A.
Importance of the subcellular location of protein deposits in neurodegenerative diseases
Current Opinion in Neurobiology e-pub: published online 6 April 2018DOI: 10.1016/j.conb.2018.03.004
PMID: 29631171
PMCID:
Date of Paper: 06/04/2018
Division: NeurobiologyEmsley P., Crispin M.
Structural analysis of glycoproteins: building N-linked glycans with Coot
Acta Crystallographica. Section D, Structural Biology 74(Pt 4):256-263. 6 April 2018DOI: 10.1107/S2059798318005119
PMID: 29652253
PMCID: PMC5892875
Date of Paper: 06/04/2018
Division: Structural StudiesGammons M., Bienz M.
Multiprotein complexes governing Wnt signal transduction
Current Opinion in Cell Biology 51:42-49DOI: 10.1016/j.ceb.2017.10.008
PMID: 29153704
PMCID:
Date of Paper: 01/04/2018
Division: Protein & Nucleic Acid ChemistryWagstaff J., Löwe J.
Prokaryotic cytoskeletons: protein filaments organizing small cells
Nature Reviews. Microbiology 16(4):187-201. April 2018DOI: 10.1038/nrmicro.2017.153
PMID: 29355854
PMCID:
Date of Paper: 01/04/2018
Division: Structural StudiesRusso C. J., Henderson R.
Ewald sphere correction using a single side-band image processing algorithm
Ultramicroscopy 187:26-33. April 2018DOI: 10.1016/j.ultramic.2017.11.001
PMID: 29413409
PMCID:
Date of Paper: 01/04/2018
Division: Structural Studies
Download pdfRusso C. J., Henderson R.
Charge accumulation in electron cryomicroscopy
Ultramicroscopy 187:43-49. April 2018DOI: 10.1016/j.ultramic.2018.01.009
PMID: 29413411
PMCID:
Date of Paper: 01/04/2018
Division: Structural Studies
Download pdfRusso C. J., Henderson R.
Microscopic charge fluctuations cause minimal contrast loss in cryoEM
Ultramicroscopy 187:56-63. April 2018DOI: 10.1016/j.ultramic.2018.01.011
PMID: 29413413
PMCID:
Date of Paper: 01/04/2018
Division: Structural Studies
Download pdf