Ribeiro J, Crossan G.P.
GCNA is a histone binding protein required for spermatogonial stem cell maintenance
Nucleic Acids Research 51(10):4791-4813DOI: 10.1093/nar/gkad168
PMID: 36919611
PMCID: PMC10250205
Date of Paper: 01/06/2023
Division: Protein & Nucleic Acid ChemistryRibeiro J., Crossan G. P.
GCNA is a histone binding protein required for spermatogonial stem cell maintenance
Nucleic Acids Research 51(10):4791-4813DOI: 51(10):4791-4813
PMID: 36919611
PMCID: PMC10250205
Date of Paper: 01/06/2023
Division: Structural StudiesAgirre J, Atanasova M, Bagdonas H, Ballard CB, Baslé A, Beilsten-Edmands J, Borges RJ, Brown DG, Burgos-Mármol JJ, Berrisford JM, Bond PS, Caballero I, Catapano L, Chojnowski G, Cook AG, Cowtan KD, Croll TI, Debreczeni JÉ, Devenish NE, Dodson EJ, Drevon TR, Emsley P, Evans G, Evans PR, Fando M, Foadi J, Fuentes-Montero L, Garman EF, Gerstel M, Gildea RJ, Hatti K, Hekkelman ML, Heuser P, Hoh SW, Hough MA, Jenkins HT, Jiménez E, Joosten RP, Keegan RM, Keep N, Krissinel EB, Kolenko P, Kovalevskiy O, Lamzin VS, Lawson DM, Lebedev AA, Leslie AGW, Lohkamp B, Long F, Malý M, McCoy AJ, McNicholas SJ, Medina A, Millán C, Murray JW, Murshudov GN, Nicholls RA, Noble MEM, Oeffner R, Pannu NS, Parkhurst JM, Pearce N, Pereira J, Perrakis A, Powell HR, Read RJ, Rigden DJ, Rochira W, Sammito M, Sánchez Rodríguez F, Sheldrick GM, Shelley KL, Simkovic F, Simpkin AJ, Skubak P, Sobolev E, Steiner RA, Stevenson K, Tews I, Thomas JMH, Thorn A, Valls JT, Uski V, Usón I, Vagin A, Velankar S, Vollmar M, Walden H, Waterman D, Wilson KS, Winn MD, Winter G, Wojdyr M, Yamashita K.
The CCP4 suite: integrative software for macromolecular crystallography
Acta crystallographica. Section D, Structural Biology 79(Pt 6):449-461DOI: 10.1107/s2059798323003595
PMID: 37259835
PMCID: PMC10233625
Date of Paper: 30/05/2023
Division: Structural StudiesBravo-Plaza I., Tagua V. G., Arst H. N. Jr, Alonso A., Pinar M., Monterroso B., Galindo A., Peñalva M. A.
The Uso1 globular head interacts with SNAREs to maintain viability even in the absence of the coiled-coil domain
Elife 12:e85079DOI: 10.7554/elife.85079
PMID: 37249218
PMCID: PMC10275640
Date of Paper: 30/05/2023
Division: Cell BiologyHakanpää L., Abouelezz A., Lenaerts A. S., Culfa S., Algie M., Bärlund J., Katajisto P., McMahon H., Almeida-Souza L.
Reticular adhesions are assembled at flat clathrin lattices and opposed by active integrin α5β1
The Journal of Cell Biology 222(8):e202303107DOI: 10.1083/jcb.202303107
PMID: 37233325
PMCID: PMC10225744
Date of Paper: 26/05/2023
Division: NeurobiologyZhang D., Lape R., Shaikh S. A., Kohegyi B. K., Watson J. F., Cais O., Nakagawa T., Greger I. H
Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics
Nature Communication 14(1):1659DOI: 10.1038/s41467-023-37259-5
PMID: 36966141
PMCID: PMC10039940
Date of Paper: 25/05/2023
Division: NeurobiologyTaisz I., Donà E., Münch D., Bailey S. N., Morris B. J., Meechan K. I., Stevens K. M., Varela-Martínez I., Gkantia M., Schlegel P., Ribeiro C., Jefferis G. S. X. E., Galili D. S.
Generating parallel representations of position and identity in the olfactory system
Cell 186(12):2556-2573.e22DOI: 10.1016/j.cell.2023.04.038
PMID: 37236194
PMCID:
Date of Paper: 25/05/2023
Division: NeurobiologyLemus L., Hegde R. S, Goder V.
New frontiers in quality control: the case of GPI-anchored proteins
Nature reviews. Molecular Cell BiologyDOI: 10.1038/s41580-023-00616-9
PMID: 37231113
PMCID:
Date of Paper: 25/05/2023
Division: Cell BiologyGong GQ, Bilanges B, Allsop B, Masson GR, Roberton V, Askwith T, Oxenford S, Madsen RR, Conduit SE, Bellini D, Fitzek M, Collier M, Najam O, He Z, Wahab B, McLaughlin SH, Chan AWE, Feierberg I, Madin A, Morelli D, Bhamra A, Vinciauskaite V, Anderson KE, Surinova S, Pinotsis N, Lopez-Guadamillas E, Wilcox M, Hooper A, Patel C, Whitehead MA, Bunney TD, Stephens LR, Hawkins PT, Katan M, Yellon DM, Davidson SM, Smith DM, Phillips JB, Angell R, Williams RL, Vanhaesebroeck B
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Nature 618(7963):159-168DOI: 10.1038/s41586-023-05972-2
PMID: 37225977
PMCID: PMC7614683
Date of Paper: 24/05/2023
Division: Protein & Nucleic Acid ChemistryGáspár I., Phea L. J, McClintock M. A., Heber S., Bullock S. L, Ephrussi A.
An RNA-based feed-forward mechanism ensures motor switching in oskar mRNA transport
The Journal of Cell Biology 222(7):e202301113DOI: 10.1083/jcb.202301113
PMID: 37213090
PMCID: 10202831
Date of Paper: 22/05/2023
Division: Cell BiologyJavitt A, Shmueli MD, Kramer MP, Kolodziejczyk AA, Cohen IJ, Radomir L, Sheban D, Kamer I, Litchfield K, Bab-Dinitz E, Zadok O, Neiens V, Ulman A, Wolf-Levy H, Eisenberg-Lerner A, Kacen A, Alon M, Rêgo AT, Stacher-Priehse E, Lindner M, Koch I, Bar J, Swanton C, Samuels Y, Levin Y, da Fonseca PCA, Elinav E, Friedman N, Meiners S, Merbl Y.
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC
Nature Cancer 4(5):629-647DOI: 10.1038/s43018-023-00557-4
PMID: 37217651
PMCID:
Date of Paper: 22/05/2023
Division: Structural StudiesWit N., Gogola E., West J. A., Vornbäumen T., Seear R. V., Bailey P. S. J., Burgos-Barragan G., Wang M., Krawczyk P., Huberts D. H. E. W., Gergely F., Matheson N. J., Kaser A., Nathan J. A., Patel K. J.
A histone deacetylase 3 and mitochondrial complex I axis regulates toxic formaldehyde production
Science Advances 9(20):eadg2235DOI: 10.1126/sciadv.adg2235
PMID: 37196082
PMCID: PMC10191432
Date of Paper: 17/05/2023
Division: Protein & Nucleic Acid ChemistryOuellet S., Ferguson L., Lau A. Z, Lim T. K. Y.
CysPresso: a classification model utilizing deep learning protein representations to predict recombinant expression of cysteine-dense peptides
BMC Bioinformatics 24(1):200DOI: 10.1186/s12859-023-05327-8
PMID: 37193950
PMCID: PMC10189939
Date of Paper: 16/05/2023
Division: NeurobiologyPatton A. P., Morris E. L., McManus D., Wang H., Li Y., Chin J. W., Hastings M. H.
Astrocytic control of extracellular GABA drives circadian timekeeping in the suprachiasmatic nucleus
Proceedings of the National Academy of Sciences of the United States of America 120(21):e2301330120DOI: 10.1073/pnas.2301330120
PMID: 37186824
PMCID: PMC10214171
Date of Paper: 15/05/2023
Division: Protein & Nucleic Acid ChemistryStern A. M., Yang Y., Jin S., Yamashita K., Meunier A. L., Liu W., Cai Y., Ericsson M., Liu L., Goedert M., Scheres S. H. W., Selkoe D. J.
Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains
Neuron 111(13):2012-2020.e4DOI: 10.1016/j.neuron.2023.04.007
PMID: 37167969
PMCID:
Date of Paper: 10/05/2023
Division: Structural StudiesWozny M.R., Di Luca A., Morado D. R., Picco A., Khaddaj R,. Campomanes P., Ivanović L., Hoffmann P. C., Miller E. A, Vanni S., Kukulski W.
In situ architecture of the ER-mitochondria encounter structure
Nature 618(7963):188-192DOI: 10.1038/s41586-023-06050-3
PMID: 37165187
PMCID: PMC7614606
Date of Paper: 10/05/2023
Division: Cell BiologyBafna A., Banks G., Hastings M. H., Nolan P. M.
Dynamic modulation of genomic enhancer elements in the suprachiasmatic nucleus, the site of the mammalian circadian clock
Genome Research 33(5):673-688DOI: 10.1101/gr.277581.122
PMID: 37156620
PMCID: PMC10317116
Date of Paper: 08/05/2023
Division: NeurobiologyGreen N. J., Russell D. A., Tanner S. H., Sutherland J. D.
Prebiotic Synthesis of N-Formylaminonitriles and Derivatives in Formamide
Journal of the American Chemical Society 145(19):10533-10541DOI: doi.org/10.1021/jacs.2c13306
PMID: 37146260
PMCID: PMC10197134
Date of Paper: 05/05/2023
Division: Protein & Nucleic Acid ChemistryQi C., Hasegawa M., Takao M., Sakai M., Sasaki M., Mizutani M., Akagi A., Iwasaki Y., Miyahara H., Yoshida M., Scheres S. H. W., Goedert M.
Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy
Acta Neuropathologica Communications 11(1):74DOI: 10.1186/s40478-023-01565-2
PMID: 37143123
PMCID: PMC10161654
Date of Paper: 05/05/2023
Division: Structural StudiesYamashita K., Wojdyr M., Long F., Nicholls R. A., Murshudov G. N.
GEMMI and Servalcat restrain REFMAC5
Acta crystallographica. Section D, Structural Biology 79(Pt 5):368-373DOI: 10.1107/s2059798323002413
PMID: 37158197
PMCID: PMC10167671
Date of Paper: 04/05/2023
Division: Structural StudiesDhillon P., Skourti E., Passmore L. A.
In conversation with Lori Passmore
The FEBS JournalDOI: 10.1111/febs.16782
PMID: 37138518
PMCID:
Date of Paper: 03/05/2023
Division: Structural StudiesShiu P. K., Sterne G. R., Spiller N., Franconville R., Sandoval A., Zhou J., Simha N., Kang C. H., Yu S., Kim J. S., Dorkenwald S., Matsliah A., Schlegel P., Yu S. C., McKellar C. E., Sterling A., Costa M., Eichler K., Jefferis G. S. X. E., Murthy M., Bates A. S., Eckstein N., Funke J., Bidaye S. S., Hampel S., Seeds A. M., Scott K.
A leaky integrate-and-fire computational model based on the connectome of the entire adult Drosophila brain reveals insights into sensorimotor processing
bioRxivDOI: 10.1101/2023.05.02.539144
PMID: PPR653992
PMCID:
Date of Paper: 02/05/2023
Division: NeurobiologyLiu T., Meng Z., Liu J., Li J., Zhang Y., Deng Z., Luo S., Wang M., Huang Q., Zhang S., Fendt P., Devouassoux J., Li D., McKenzie A. N. J., Nahrendorf M., Libby P., Guo J., Shi G. P.
Group 2 innate lymphoid cells protect mouse heart from myocardial infarction injury via interleukin 5, eosinophils, and dendritic cells
Cardiovascular Research 119(4):1046-1061DOI: 10.1093/cvr/cvac144
PMID: 36063432
PMCID: PMC10153644
Date of Paper: 01/05/2023
Division: Protein & Nucleic Acid ChemistryGerecht K., Freund N., Liu W., Liu Y., Fürst M. J. L. J., Holliger P.
The Expanded Central Dogma: Genome Resynthesis, Orthogonal Biosystems, Synthetic Genetics
Annual Review of Biophysics 52:413-432DOI: 10.1146/annurev-biophys-111622-091203
PMID: 37159296
PMCID: PMC7614659
Date of Paper: 01/05/2023
Division: Protein & Nucleic Acid ChemistryKäshammer L., van den Ent F., Jeffery M., Jean N. L., Hale V. L., Löwe J.
Cryo-EM structure of the bacterial divisome core complex and antibiotic target FtsWIQBL
Nature Microbiology 8(6):1149-1159DOI: doi.org/10.1038/s41564-023-01368-0
PMID: 37127704
PMCID: PMC7614612
Date of Paper: 01/05/2023
Division: Structural Studies