Takai H., Aria V., Borges P., Yeeles J. T. P., de Lange T.
CST-polymerase α-primase solves a second telomere end-replication problem
Nature 627(8004):664-670DOI: 10.1038/s41586-024-07137-1
PMID: 38418884
PMCID:
Date of Paper: 28/02/2024
Division: Protein & Nucleic Acid ChemistryFellows A. D., Bruntraeger M., Burgold T., Bassett A. R., Carter A. P.
Dynein and dynactin move long-range but are delivered separately to the axon tip
The Journal of Cell Biology 223(5):e202309084DOI: 10.1083/jcb.202309084
PMID: 38407313
PMCID: PMC10896695
Date of Paper: 26/02/2024
Division: Structural StudiesJamali K., Käll L., Zhang R., Brown A., Kimanius D., Scheres S. H. W.
Automated model building and protein identification in cryo-EM maps
Nature 628(8007):450-457DOI: 10.1038/s41586-024-07215-4
PMID: 38408488
PMCID: PMC11006616
Date of Paper: 26/02/2024
Division: Structural StudiesHegde RS.
How to enjoy and thrive in graduate school
Trends in Cell Biology S0962-8924(24)00027-8DOI: 10.1016/j.tcb.2024.02.003
PMID: 38402006
PMCID:
Date of Paper: 23/02/2024
Division: Cell BiologyBertolotti A.
Keeping goblet cells unstressed: new insights into a general principle
The EMBO Journal 43(5):663-665DOI: 10.1038/s44318-024-00041-4
PMID: 38308018
PMCID: PMC10907747
Date of Paper: 02/02/2024
Division: NeurobiologyImaz-Rosshandler I., Rode C., Guibentif C., Harland L. T. G., Ton M. N, Dhapola P., Keitley D., Argelaguet R., Calero-Nieto F. J., Nichols J., Marioni J. C., de Bruijn M. F. T. R., Göttgens B.
Tracking early mammalian organogenesis - prediction and validation of differentiation trajectories at whole organism scale
Development 151(3):dev201867DOI: 10.1242/dev.201867
PMID: 37982461
PMCID: PMC10906099
Date of Paper: 31/01/2024
Division: Cell BiologyHeber S., McClintock M. A., Simon B., Mehtab E, Lapouge K., Hennig J., Bullock S. L., Ephrussi A.
Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport
Nature Structural & Molecular BiologyDOI: 10.1038/s41594-024-01212-x
PMID: 38297086
PMCID:
Date of Paper: 30/01/2024
Division: Cell BiologyGhanim G. E., Sekne Z., Balch S., van Roon A. M, Nguyen T. H. D.
2.7 Å cryo-EM structure of human telomerase H/ACA ribonucleoprotein
Nature Communications 15(1):746DOI: 10.1038/s41467-024-45002-x
PMID: 38272871
PMCID: PMC10811338
Date of Paper: 25/01/2024
Division: Structural StudiesTian R., Rehm F B. H, Czernecki D., Gu Y., Zürcher J. F., Liu K. C., Chin J.W.
Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli
Science 383(6681):421-426DOI: 10.1126/science.adk1281
PMID: 38271510
PMCID:
Date of Paper: 25/01/2024
Division: Protein & Nucleic Acid ChemistrySaredi G, Carelli FN, Rolland SGM, Furlan G, Piquet S, Appert A, Sanchez-Pulido L, Price JL, Alcon P, Lampersberger L, Déclais AC, Ramakrishna NB, Toth R, Macartney T, Alabert C, Ponting CP, Polo SE, Miska EA, Gartner A, Ahringer J, Rouse J.
The histone chaperone SPT2 regulates chromatin structure and function in Metazoa
Nature Structural & Molecular Biology, 31(3):523-535DOI: 10.1038/s41594-023-01204-3
PMID: 38238586
PMCID: PMC7615752
Date of Paper: 18/01/2024
Division: Structural StudiesMcRae E. K. S., Wan C. J .K., Kristoffersen E. L., Hansen K., Gianni E., Gallego I., Curran J. F., Attwater J., Holliger P., Andersen E. S.
Cryo-EM structure and functional landscape of an RNA polymerase ribozyme
Proceedings of the National Academy of Sciences of the United States of America 21(3):e2313332121DOI: 10.1073/pnas.2313332121
PMID: 38207080
PMCID: PMC10801858
Date of Paper: 11/01/2024
Division: Protein & Nucleic Acid ChemistrySale J. E., Stoddard B. L.
Fifty years of Nucleic Acids Research
Nucleic Acids Research 52(1): 1–3.DOI: 10.1093/nar/gkad1156
PMID: 38178306
PMCID: PMC10783492
Date of Paper: 11/01/2024
Division: Protein & Nucleic Acid ChemistryDunkelmann D. L., Piedrafita C., Dickson A., Liu K. C., Elliott T. S., Fiedler M., Bellini D., Zhou A., Cervettini D., Chin J.
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism
Nature 10.1038/s41586-023-06897-6DOI: 10.1038/s41586-023-06897-6
PMID: 38200312
PMCID: PMC10794150
Date of Paper: 10/01/2024
Division: Protein & Nucleic Acid ChemistryVollmar M., Nicholls R., Antonyuk S.
Current trends in macromolecular model refinement and validation
Acta crystallographica 80(Pt 1):1-3DOI: 10.1107/s2059798323010823
PMID: 38127063
PMCID: PMC10833345
Date of Paper: 01/01/2024
Division: Structural StudiesMellor C., Nassar J., Šviković S., Sale J. E.
PRIMPOL ensures robust handoff between on-the-fly and post-replicative DNA lesion bypass
Nucleic Acids Research 52(1):243-258DOI: doi.org/10.1093/nar/gkad1054
PMID: 37971291
PMCID: PMC10783524
Date of Paper: 01/01/2024
Division: Protein & Nucleic Acid ChemistryLi XH, Yu CWH, Gomez-Navarro N, Stancheva V, Zhu H, Murthy A, Wozny M, Malhotra K, Johnson CM, Blackledge M, Santhanam B, Liu W, Huang J, Freund SMV, Miller EA, Babu MM.
Dynamic conformational changes of a tardigrade group-3 late embryo genesis abundant protein modulate membrane biophysical properties
PNAS Nexus 3(1): pgae006DOI: 10.1093/pnasnexus/pgae006
PMID: 38269070
PMCID: PMC10808001
Date of Paper: 01/01/2024
Division: Cell BiologyFatalska A., Hodgson G., Freund S. M. V., Maslen S. L., Morgan T., Thorkelsson S. R., van Slegtenhorst M., Lorenz S., Andreeva A., Kaat L. D., Bertolotti A.
Recruitment of trimeric eIF2 by phosphatase non-catalytic subunit PPP1R15B
Molecular Cell 84(3):506-521.e11DOI: 10.1016/j.molcel.2023.12.011
PMID: 38159565
PMCID: PMC7615683
Date of Paper: 29/12/2023
Division: NeurobiologyNeidhardt L., Cloots E., Friemel N., Weiss C. A. M., Harding H. P., McLaughlin S. H., Janssens S., Ron D.
The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells
The EMBO JournalDOI: doi.org/10.1038/s44318-023-00014-z
PMID: 38177498
PMCID:
Date of Paper: 18/12/2023
Division: Protein & Nucleic Acid ChemistryGoedert M., Crowther R. A., Scheres S. H. W., Spillantini M. G.
Tau and neurodegeneration
Cytoskeleton 81(1):95-102DOI: 10.1002/cm.21812
PMID: 38073060
PMCID: PMC7615684
Date of Paper: 10/12/2023
Division: NeurobiologyTetter S., Arseni D., Murzin A. G., Buhidma Y., Peak-Chew S. Y., Garringer H. J. Newell K. L., Vidal R., Apostolova L. G., Lashley T., Ghetti B., Ryskeldi-Falcon B.
TAF15 amyloid filaments in frontotemporal lobar degeneration
Nature, 625(7994):345-351DOI: 10.1038/s41586-023-06801-2
PMID: 38057661
PMCID: PMC10781619
Date of Paper: 06/12/2023
Division: NeurobiologyDonnelly C. M., Stewart M., Roby J. A., Sundaramoorthy V., Forwood J. K.
Structural Determination of the Australian Bat Lyssavirus Nucleoprotein and Phosphoprotein Complex
Viruses 16(1):33DOI: 10.3390/v16010033
PMID: 38229694
PMCID: PMC7615531
Date of Paper: 01/12/2023
Division: Structural StudiesLövestam S,. Li D., Wagstaff J. L., Kotecha A., Kimanius D., McLaughlin S. H., Murzin A. G., Freund S. M. V, Goedert M., Scheres S. H. W.
Disease-specific tau filaments assemble via polymorphic intermediates
Nature 625(7993):119-125DOI: 10.1038/s41586-023-06788-w
PMID: 38030728
PMCID: PMC10764278
Date of Paper: 29/11/2023
Division: Structural StudiesDrehmann P., Milanos S., Schaefer N., Kasaragod V., Herterich S, Holzbach-Eberle U., Harvey R. J.
Dual role of dysfunctional Asc-1 transporter in distinct human pathologies - human startle disease and developmental delay
eNeuro 0263-23.2023.DOI: 10.1523/ENEURO.0263-23.2023
PMID: 37903619
PMCID: PMC10668224
Date of Paper: 16/11/2023
Division: NeurobiologyLin Z., Green E. W., Webster S. G., Hastings M. H., Wilcockson D. C., Kyriacou C. P.
The circadian clock gene bmal1 is necessary for co-ordinated circatidal rhythms in the marine isopod Eurydice pulchra (Leach)
Plos Genetics 19(11):e1011047DOI: 10.1371/journal.pgen.1011047
PMID: 37967082
PMCID: PMC10651029
Date of Paper: 15/11/2023
Division: NeurobiologyDickerson J. L., Leahy E., Peet M. J., Naydenova K., Russo C. J.
Accurate magnification determination for cryoEM using gold
Ultramicroscopy 256:113883DOI: 10.1016/j.ultramic.2023.113883
PMID: 38008055
PMCID: PMC10782223
Date of Paper: 15/11/2023
Division: Structural Studies