Leyva-Castillo J. M., Galand C., Mashiko S., Bissonnette R., McGurk A., Ziegler S. F., Dong C., McKenzie A. N. J., Sarfati M., Geha R. S.
ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation
Journal of Allergy and Clinical Immunology 145(6):1606-1614.e4. June 2020DOI: 10.1016/j.jaci.2020.02.026
PMID: 32179159
PMCID: PMC7282942
Date of Paper: 01/06/2020
Division: Protein & Nucleic Acid ChemistryLucken-Ardjomande Häsler S., Vallis Y., Pasche M., McMahon H. T.
GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508
Journal of Cell Biology 219(5):e201811014. 4 May 2020DOI: 10.1083/jcb.201811014
PMID: 32344433
PMCID: PMC7199855
Date of Paper: 04/05/2020
Division: NeurobiologyDamgaard R. B., Jolin H. E., Allison M. E. D., Davies S. E., Titheradge H. L., McKenzie A. N. J., Komander D.
OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer
Cell Death and Differentiation 27(5):1457-1474. May 2020DOI: 10.1038/s41418-020-0532-1
PMID: 32231246
PMCID: PMC7206033
Date of Paper: 01/05/2020
Division: Protein & Nucleic Acid ChemistryElshenawy M. M., Kusakci E., Volz S., Baumbach J., Bullock S. L., Yildiz A.
Lis1 activates dynein motility by modulating its pairing with dynactin
Nature Cell Biology 22(5):570-578. May 2020DOI: 10.1038/s41556-020-0501-4
PMID: 32341547
PMCID:
Date of Paper: 01/05/2020
Division: Cell BiologyGuilliam T. A., Yeeles J. T. P.
Reconstitution of translesion synthesis reveals a mechanism of eukaryotic DNA replication restart
Nature Structural & Molecular Biology 27(5):450-460. May 2020DOI: 10.1038/s41594-020-0418-4
PMID: 32341533
PMCID:
Date of Paper: 01/05/2020
Division: Protein & Nucleic Acid ChemistryFlynn S. M., Chen C., Artan M., Barratt S., Crisp A., Nelson G. M., Peak-Chew S. Y., Begum F., Skehel M., de Bono M.
MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity
Nature Communications 11(1):2099. 29 April 2020DOI: 10.1038/s41467-020-15872-y
PMID: 32350248
PMCID: PMC7190641
Date of Paper: 29/04/2020
Division: Cell BiologyKrishnan A., Berthelet J., Renaud E., Rosigkeit S., Distler U., Stawiski E., Wang J., Modrusan Z., Fiedler M., Bienz M., Tenzer S., Schad A., Roth W., Thiede B., Seshagiri S., Musholt T. J., Rajalingam K.
Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas
Nature Communications 11(1):2056. 28 April 2020DOI: 10.1038/s41467-020-15955-w
PMID: 32345963
PMCID: PMC7188865
Date of Paper: 28/04/2020
Division: Protein & Nucleic Acid ChemistryBarford D.
Structural interconversions of the anaphase-promoting complex/cyclosome (APC/C) regulate cell cycle transitions
Current Opinion in Structural Biology 61:86-97. April 2020DOI: 10.1016/j.sbi.2019.11.010
PMID: 31864160
PMCID:
Date of Paper: 01/04/2020
Division: Structural StudiesLuh L. M., Bertolotti A.
Potential benefit of manipulating protein quality control systems in neurodegenerative diseases
Current Opinion in Neurobiology 61:125-132. April 2020DOI: 10.1016/j.conb.2020.02.009
PMID: 32199101
PMCID:
Date of Paper: 01/04/2020
Division: NeurobiologyEschbach C., Fushiki A., Winding M., Schneider-Mizell C. M., Shao M., Arruda R., Eichler K., Valdes-Aleman J., Ohyama T., Thum A. S., Gerber B., Fetter R. D., Truman J. W., Litwin-Kumar A., Cardona A., Zlatic M.
Recurrent architecture for adaptive regulation of learning in the insect brain
Nature Neuroscience 23(4):544-555. April 2020DOI: 10.1038/s41593-020-0607-9
PMID: 32203499
PMCID:
Date of Paper: 01/04/2020
Division: NeurobiologyYang N., Smyllie N. J., Morris H., Gonçalves C. F., Dudek M., Pathiranage D., Chesham J. E., Adamson A., Spiller D., Zindy E., Bagnall J., Humphreys N., Hoyland J., Loudon A. S. I., Hastings M. H., Meng Q. J.
Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator
Plos Genetics 16(4):e1008729. April 2020DOI: 10.1371/journal.pgen.1008729
PMID: 32352975
PMCID: PMC7217492
Date of Paper: 01/04/2020
Division: NeurobiologyManton J. D., Ströhl F., Fiolka R., Kaminski C. F., Rees E. J.
Concepts for structured illumination microscopy with extended axial resolution through mirrored illumination
Biomedical Optics Express 11(4):2098-2108. 1 April 2020DOI: 10.1364/boe.382398
PMID: 32341869
PMCID: PMC7173891
Date of Paper: 01/04/2020
Division: Cell BiologyTan L., Wang Q., Zhang D., Ding J., Huang Q., Tang Y.Q., Wang Q., Miao H.
Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study
Signal Transduction and Targeted Therapy 5(1):33. 27 March 2020DOI: 10.1038/s41392-020-0148-4
PMID: 32296069
PMCID: PMC7100419
Date of Paper: 27/03/2020
Division: NeurobiologyHodskinson M. R., Bolner A., Sato K., Kamimae-Lanning A. N., Rooijers K., Witte M., Mahesh M., Silhan J., Petek M., Williams D. M., Kind J., Chin J. W., Patel K. J., Knipscheer P.
Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms
Nature 579(7800):603-608. 26 March 2020DOI: 10.1038/s41586-020-2059-5
PMID: 32132710
PMCID:
Date of Paper: 26/03/2020
Division: Protein & Nucleic Acid ChemistryMorgan S. A., Lavenir I., Fan J., Masuda-Suzukake M., Passarella D., DeTure M. A., Dickson D. W., Ghetti B., Goedert M.
α-Synuclein filaments from transgenic mouse and human synucleinopathy-containing brains are major seed-competent species
Journal of Biological Chemistry 295(19):6652-6664. 24 March 2020DOI: 10.1074/jbc.ra119.012179
PMID: 32209651
PMCID: PMC7212628
Date of Paper: 24/03/2020
Division: NeurobiologyWoldegebriel R., Kvist J., Andersson N., Õunap K., Reinson K., Wojcik M. H., Bijlsma E. K., Hoffer M. J. V., Ryan M. M., Stark Z., Walsh M., Cuppen I., van den Boogaard M. H., Bharucha-Goebel D., Donkervoort S., Winchester S., Zori R., Bönnemann C. G., Maroofian R., O'Connor E.Houlden H., Zhao F., Carpén O., White M., Sreedharan J., Stewart M., Ylikallio E., Tyynismaa H.
Distinct effects on mRNA export factor GANP underlie neurological disease phenotypes and alter gene expression depending on intron content
Human Molecular Genetics 29(9):1426-1439. 19 March 2020DOI: 10.1093/hmg/ddaa051
PMID: 32202298
PMCID: PMC7297229
Date of Paper: 19/03/2020
Division: Structural StudiesAuer T. O., Khallaf M. A., Silbering A. F., Zappia G., Ellis K., Álvarez-Ocaña R., Arguello J. R., Hansson B. S., Jefferis G. S. X. E., Caron S. J. C., Knaden M., Benton R.
Olfactory receptor and circuit evolution promote host specialization
Nature 579(7799):402-408. 19 March 2020DOI: 10.1038/s41586-020-2073-7
PMID: 32132713
PMCID:
Date of Paper: 19/03/2020
Division: NeurobiologySlodkowicz G., Goldman N.
Integrated structural and evolutionary analysis reveals common mechanisms underlying adaptive evolution in mammals
Proceedings of the National Academy of Sciences of the United States of America 117(11):5977-5986. 17 March 2020DOI: 10.1073/pnas.1916786117
PMID: 32123117
PMCID:
Date of Paper: 17/03/2020
Division: Structural StudiesParigoris E., Dunkelmann D. L., Murphy A., Wili N., Kaech A., Dumrese C., Jimenez-Rojo N., Silvan U.
Facile generation of giant unilamellar vesicles using polyacrylamide gels
Scientific Reports 10(1):4824. 16 March 2020DOI: 10.1038/s41598-020-61655-2
PMID: 32179778
PMCID: PMC7075891
Date of Paper: 16/03/2020
Division: Protein & Nucleic Acid ChemistryPamula F., Mühle J., Blanc A., Nehmé R., Edwards P. C., Tate C. G., Tsai C. J.
Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization
Journal of Visualized Experiments : Jove 157:e60747. 16 March 2020DOI: 10.3791/60747
PMID: 32225143
PMCID: PMC7250641
Date of Paper: 16/03/2020
Division: Structural StudiesHervas R., Rau M. J., Park Y., Zhang W., Murzin A. G., Fitzpatrick J. A. J., Scheres S. H. W., Si K.
Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila
Science 367(6483):1230-1234. 13 March 2020DOI: 10.1126/science.aba3526
PMID: 32165583
PMCID:
Date of Paper: 13/03/2020
Division: Structural StudiesOrdureau A., Paulo J. A., Zhang J., An H., Swatek K. N., Cannon J. R., Wan Q., Komander D., Harper J. W.
Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling
Molecular Cell 77(5):1124-1142.e10. 5 March 2020DOI: 10.1016/j.molcel.2019.11.013
PMID: 32142685
PMCID: PMC7098486
Date of Paper: 05/03/2020
Division: Protein & Nucleic Acid ChemistryChen Y. L., Gomes T., Hardman C. S., Vieira Braga F. A., Gutowska-Owsiak D., Salimi M., Gray N., Duncan D. A., Reynolds G., Johnson D.,Salio M., Cerundolo V., Barlow J. L., McKenzie A. N. J., Teichmann S. A.,Haniffa M., Ogg G.
Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation
Journal of Experimental Medicine 217(3):e20190811. 2 March 2020DOI: 10.1084/jem.20190811
PMID: 31845972
PMCID:
Date of Paper: 02/03/2020
Division: Protein & Nucleic Acid ChemistryVisentin S., Cannone G., Doutch J., Harris G., Gleghorn M. L., Clifton L.,Smith B. O., Spagnolo L.
A multi-pronged approach to understanding the form and function of hStaufen protein
RNA 26(3):265-277. March 2020DOI: 10.1261/rna.072595.119
PMID: 31852734
PMCID:
Date of Paper: 01/03/2020
Division: Structural StudiesMuir K. W., Li Y., Weis F., Panne D.
The structure of the cohesin ATPase elucidates the mechanism of SMC-kleisin ring opening
Nature Structural & Molecular Biology 27: 233-239. March 2020DOI: 10.1038/s41594-020-0379-7
PMID: 32066964
PMCID:
Date of Paper: 01/03/2020
Division: Structural Studies