Tsuchiya Y., Byrne D. P., Burgess S. G., Bormann J., Baković J., Huang Y., Zhyvoloup A., Yu B. Y. K., Peak-Chew S., Tran T., Bellany F., Tabor A. B., Chan A. E., Guruprasad L., Garifulin O., Filonenko V., Vonderach M., Ferries S., Eyers C. E., Carroll J., Skehel M., Bayliss R., Eyers P. A., Gout I.
Covalent Aurora A regulation by the metabolic integrator coenzyme A
Redox Biology 28:101318. January 2020DOI: 10.1016/j.redox.2019.101318
PMID: 31546169
PMCID:
Date of Paper: 01/01/2020
Division: Cell BiologyKumar A., Clerici M., Muckenfuss L. M., Passmore L. A., Jinek M.
Mechanistic insights into mRNA 3'-end processing
Current Opinion in Structural Biology 59:143-150. December 2019DOI: 10.1016/j.sbi.2019.08.001
PMID: 31499460
PMCID:
Date of Paper: 01/12/2019
Division: Structural Studies
Download pdfBaković J., Yu B. Y. K., Silva D., Chew S. P., Kim S., Ahn S. H., Palmer L., Aloum L., Stanzani G., Malanchuk O., Duchen M. R., Singer M., Filonenko V., Lee T. H., Skehel M., Gout I.
A key metabolic integrator, coenzyme A, modulates the activity of peroxiredoxin 5 via covalent modification
Molecular and Cellular Biochemistry 461(1-2):91-102. November 2019DOI: 10.1007/s11010-019-03593-w
PMID: 31375973
PMCID:
Date of Paper: 01/11/2019
Division: Cell BiologyWu C., Travers A.
Modelling and DNA topology of compact 2-start and 1-start chromatin fibres
Nucleic Acids Research 47(18):9902-9924. 10 October 2019DOI: 10.1093/nar/gkz495
PMID: 31219588
PMCID: PMC6765122
Date of Paper: 10/10/2019
Division: Cell Biology
Download pdfWinter G.
Harnessing Evolution to Make Medicines (Nobel Lecture)
Angewandte Chemie 58(41):14438-14445. 7 October 2019DOI: 10.1002/anie.201909343
PMID: 31529671
PMCID:
Date of Paper: 07/10/2019
Division: Protein & Nucleic Acid ChemistryToste Rêgo A., da Fonseca P. C. A.
Characterization of Fully Recombinant Human 20S and 20S-PA200 Proteasome Complexes
Molecular Cell 76(1):138-147.e5. 3 October 2019DOI: 10.1016/j.molcel.2019.07.014
PMID: 31473102
PMCID:
Date of Paper: 03/10/2019
Division: Structural Studies
Download pdfCasañal A., Shakeel S., Passmore L. A.
Interpretation of medium resolution cryoEM maps of multi-protein complexes
Current Opinion in Structural Biology 58:166-174. October 2019DOI: 10.1016/j.sbi.2019.06.009
PMID: 31362190
PMCID:
Date of Paper: 01/10/2019
Division: Structural Studies, Cell Biology
Download pdfGonzález-Rueda A., Tripodi M.
Éloge de la Fuite: Neural Circuits for Avoiding Dangerous Situations
Trends in Neurosciences 42(10):657-659. October 2019DOI: 10.1016/j.tins.2019.07.006
PMID: 31399288
PMCID:
Date of Paper: 01/10/2019
Division: NeurobiologyKlein A. F., Varela M. A., Arandel L., Holland A., Naouar N., Arzumanov A., Seoane D., Revillod L., Bassez G., Ferry A., Jauvin D., Gourdon G., Puymirat J., Gait M. J., Furling D., Wood M. J.
Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice
The Journal of Clinical Investigation e-pub: published online 30 September 2019DOI: 10.1172/JCI128205
PMID: 31479430
PMCID:
Date of Paper: 30/09/2019
Division: Protein & Nucleic Acid ChemistryHeiby J. C., Goretzki B., Johnson C. M., Hellmich U. A., Neuweiler H.
Methionine in a protein hydrophobic core drives tight interactions required for assembly of spider silk
Nature Communications 10(1):4378. 26 September 2019DOI: 10.1038/s41467-019-12365-5
PMID: 31558722
PMCID: PMC6763431
Date of Paper: 26/09/2019
Division: Protein & Nucleic Acid Chemistry
Download pdfTakeda A. J., Maher T. J., Zhang Y., Lanahan S. M., Bucklin M. L., Compton S. R., Tyler P. M., Comrie W. A., Matsuda M., Olivier K. N., Pittaluga S., McElwee J. J., Long Priel D. A., Kuhns D. B., Williams R. L., Mustillo P. J., Wymann M. P., Koneti Rao V., Lucas C. L.
Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology
Nature Communications 10(1):4364. 25 September 2019DOI: 10.1038/s41467-019-12311-5
PMID: 31554793
PMCID: PMC6761123
Date of Paper: 25/09/2019
Division: Protein & Nucleic Acid Chemistry
Download pdfFicht X., Ruef N., Stolp B., Samson G. P. B., Moalli F., Page N., Merkler D., Nichols B. J., Diz-Muñoz A., Legler D. F., Niggli V., Stein J. V.
In Vivo Function of the Lipid Raft Protein Flotillin-1 during CD8+ T Cell-Mediated Host Surveillance
Journal of Immunology e-pub: published online 23 September 2019DOI: 10.4049/jimmunol.1900075
PMID: 31548330
PMCID:
Date of Paper: 23/09/2019
Division: Cell BiologyStangl A., Elliott P. R., Pinto-Fernandez A., Bonham S., Harrison L., Schaub A., Kutzner K., Keusekotten K., Pfluger P. T., El Oualid F., Kessler B. M., Komander D., Krappmann D.
Regulation of the endosomal SNX27-retromer by OTULIN
Nature Communications 10(1):4320. 20 September 2019DOI: 10.1038/s41467-019-12309-z
PMID: 31541095
PMCID: PMC6754446
Date of Paper: 20/09/2019
Division: Protein & Nucleic Acid Chemistry
Download pdfLetts J. A., Fiedorczuk K., Degliesposti G., Skehel M., Sazanov L. A.
Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk
Molecular Cell 75(6):1131-1146.e6. 19 September 2019DOI: 10.1016/j.molcel.2019.07.022
PMID: 31492636
PMCID:
Date of Paper: 19/09/2019
Division: Cell BiologyPerera L. A., Rato C., Yan Y., Neidhardt L., McLaughlin S. H., Read R. J., Preissler S., Ron D.
An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP
EMBO Journal e-pub: published online 18 September 2019DOI: 10.15252/embj.2019102177
PMID: 31531998
PMCID:
Date of Paper: 18/09/2019
Division: Protein & Nucleic Acid Chemistry
Download pdfLavenir I., Passarella D., Masuda-Suzukake M., Curry A., Holton J. L., Ghetti B., Goedert M.
Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson's disease brain extracts in transgenic mice
Acta Neuropathologica Communications 7(1):148. 16 September 2019DOI: 10.1186/s40478-019-0804-5
PMID: 31522685
PMCID: PMC6745790
Date of Paper: 16/09/2019
Division: Neurobiology
Download pdfWatson J. F., García-Nafría J.
In vivo DNA assembly using common laboratory bacteria: a re-emerging tool to simplify molecular cloning
Journal of Biological Chemistry e-pub: published online 14 September 2019DOI: 10.1074/jbc.REV119.009109
PMID: 31522138
PMCID:
Date of Paper: 14/09/2019
Division: NeurobiologyChandler L. C., Barnard A. R., Caddy S. L., Patrício M. I., McClements M. E., Fu H., Rada C., MacLaren R. E., Xue K.
Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues
Molecular Therapy. Methods & Clinical Development 14:77-89. 13 September 2019DOI: 10.1016/j.omtm.2019.05.012
PMID: 31309129
PMCID: PMC6606965
Date of Paper: 13/09/2019
Division: Protein & Nucleic Acid Chemistry
Download pdfCohn J., Dwivedi V., Valperga G., Zarate N., de Bono M., Horvitz H. R., Pierce J. T.
Activity-Dependent Regulation of the Proapoptotic BH3-Only Gene egl-1 in a Living Neuron Pair in Caenorhabditis elegans
G3 e-pub: published online 13 September 2019DOI: 10.1534/g3.119.400654
PMID: 31519744
PMCID:
Date of Paper: 13/09/2019
Division: Cell BiologySathyanarayanan N., Cannone G., Gakhar L., Katagihallimath N., Sowdhamini R., Ramaswamy S., Vinothkumar K. R.
Molecular basis for metabolite channeling in a ring opening enzyme of the phenylacetate degradation pathway
Nature Communications 10(1):4127. 11 September 2019DOI: 10.1038/s41467-019-11931-1
PMID: 31511507
PMCID: PMC6739347
Date of Paper: 11/09/2019
Division: Structural Studies
Download pdfDeng X., Gonzalez Llamazares A., Wagstaff J. M., Hale V. L., Cannone G., McLaughlin S. H., Kureisaite-Ciziene D., Löwe J.
The structure of bactofilin filaments reveals their mode of membrane binding and lack of polarity
Nature Microbiology e-pub: published online 9 September 2019DOI: 10.1038/s41564-019-0544-0
PMID: 31501539
PMCID:
Date of Paper: 09/09/2019
Division: Structural StudiesMasullo L., Mariotti L., Alexandre N., Freire-Pritchett P., Boulanger J., Tripodi M.
Genetically Defined Functional Modules for Spatial Orienting in the Mouse Superior Colliculus
Current Biology 29(17):2892-2904.e8. 9 September 2019DOI: 10.1016/j.cub.2019.07.083
PMID: 31474533
PMCID: PMC6739420
Date of Paper: 09/09/2019
Division: Neurobiology, Cell Biology
Download pdfWelch L. G., Munro S.
A tale of short tails, through thick and thin: investigating the sorting mechanisms of Golgi enzymes
FEBS Letters 593(17):2452-2465. September 2019DOI: 10.1002/1873-3468.13553
PMID: 31344261
PMCID:
Date of Paper: 01/09/2019
Division: Cell Biology
Download pdfParsons H. T., Stevens T. J., McFarlane H. E., Vidal-Melgosa S., Griss J., Lawrence N., Butler R., Sousa M. M. L., Salemi M., Willats W. G. T., Petzold C. J., Heazlewood J. L., Lilley K. S.
Separating Golgi Proteins from Cis to Trans Reveals Underlying Properties of Cisternal Localization
Plant Cell 31(9):2010-2034. September 2019DOI: 10.1105/tpc.19.00081
PMID: 31266899
PMCID:
Date of Paper: 01/09/2019
Division: Cell BiologyToropova K., Zalyte R., Mukhopadhyay A. G., Mladenov M., Carter A. P., Roberts A. J.
Structure of the dynein-2 complex and its assembly with intraflagellar transport trains
Nature Structural & Molecular Biology 26(9):823-829. September 2019DOI: 10.1038/s41594-019-0286-y
PMID: 31451806
PMCID:
Date of Paper: 01/09/2019
Division: Structural Studies