Maldutyte J., Li X.H., Gomez-Navarro N., Robertson E.G., Miller E.A.
ER export via SURF4 uses diverse mechanisms of both client and coat engagement
The Journal of Cell Biology 224(1):e202406103DOI: 10.1083/jcb.202406103
PMID: 39531033
PMCID: PMC11557686
Date of Paper: 06/01/2025
Division: Cell BiologyKrüger L.K., Watson J.L., Derivery E.
Synthetic engineering of cortical polarity during mitosis using designed proteins
Methods in Molecular Biology 2872:247-255DOI: 10.1007/978-1-0716-4224-5_17
PMID: 39616581
PMCID:
Date of Paper: 01/01/2025
Division: Cell BiologyBabai K.H., Long F., Malý M., Yamashita K., Murshudov G.N.
Improving macromolecular structure refinement with metal-coordination restraints
Acta crystallographica. Section D, Structural Biology 80(Pt 12):821-833DOI: 10.1107/s2059798324011458
PMID: 39625466
PMCID: PMC11626771
Date of Paper: 03/12/2024
Division: Structural StudiesBu F., Adam Y., Adamiak R.W., Antczak M., de Aquino B.R.H., Badepally N.G., Batey R.T., Baulin E.F., Boinski P., Boniecki M.J., Bujnicki J.M., Carpenter K.A., Chacon J., Chen S.J., Chiu W., Cordero P., Das N.K., Dad R., Dawson W.K., DiMaio F., Ding F., Dock-Bregeon A.C., Dokholyan N.V., Dror R.O., Dunin-Horkawicz S., Eismann S., Ennifar E., Esmaeeli R., Farsani M.A., Ferré-D'Amaré A.R., Geniesse C., Ghanim G.E., Guzman H.V., Hood I.V., Huang L., Jain D.S., Jaryani F., Jin L., Joshi A., Karelina M., Kieft J.S., Kladwang W., Kmiecik S., Koirala D., Kollmann M., Kretsch R.C., Kurciński M., Li J., Li S., Magnus M., Masquida B., Moafinejad S.N., Mondal A., Mukherjee S., Nguyen T.H.D., Nikolaev G., Nithin C., Nye G., Jeyeram I.P.N.P., Perez A., Pham P., Piccirilli J.A., Pilla S.P., Pluta R., Poblete S., Ponce-Salvatierra A., Popenda M., Popenda L., Pucci F., Rangan R., Ray A., Ren A., Sarzynska J., Sha C.M., Stefaniak F., Su Z., Suddala K.C., Szachniuk M., Townshend R., Trachman R.H., Wang J., Wang W., Watkins A., Wirecki T.K., Xiao Y., Xiong P., Xiong Y., Yang J., Yesselman J.D., Zhang J., Zhang Y., Zhang Z., Zhou Y., Zok T., Zhang D., Zhang S., Żyła A., Westhof E., Miao Z.
RNA-Puzzles Round V: blind predictions of 23 RNA structures
Nature MethodsDOI: 10.1038/s41592-024-02543-9
PMID: 39623050
PMCID:
Date of Paper: 02/12/2024
Division: Structural StudiesGong G.Q., Anandapadamanaban M., Islam M.S., Hay I.M., Bourguet M., Špokaitė S., Dessus A.N., Ohashi Y., Perisic O., Williams R.L.
Making PI3K superfamily enzymes run faster
Advances in Biological Regulation :101060DOI: 10.1016/j.jbior.2024.101060
PMID: 39592347
PMCID:
Date of Paper: 19/11/2024
Division: Protein & Nucleic Acid ChemistrySakata R.C., Shahbazi M.N.
Building a molecular reference map of the human embryo
Nature MethodsDOI: 10.1038/s41592-024-02494-1
PMID: 39543282
PMCID:
Date of Paper: 14/11/2024
Division: Cell BiologySit T.P.H., Feord R.C., Dunn A.W.E., Chabros J., Oluigbo D., Smith H.H., Burn L., Chang E., Boschi A., Yuan Y., Gibbons G.M., Khayat-Khoei M., De Angelis F., Hemberg E., Hemberg M., Lancaster M.A., Lakatos A., Eglen S.J., Paulsen O., Mierau S.B.
MEA-NAP: A flexible network analysis pipeline for neuronal 2D and 3D organoid multielectrode recordings
Cell Reports Methods 4(11):100901DOI: 10.1016/j.crmeth.2024.100901
PMID: 39520988
PMCID:
Date of Paper: 08/11/2024
Division: Cell BiologyPyle E., Miller E.A., Zanetti G.
Cryo-electron tomography reveals how COPII assembles on cargo-containing membranes
Nature Structural & Molecular BiologyDOI: 10.1038/s41594-024-01413-4
PMID: 39511455
PMCID:
Date of Paper: 07/11/2024
Division: Cell BiologyGhetti B., Schweighauser M., Jacobsen M.H., Gray D., Bacioglu M., Murzin A.G., Glazier B.S., Katsinelos T., Vidal R., Newell K.L., Gao S., Garringer H.J., Spillantini M.G., Scheres S.H.W., Goedert M.
TMEM106B amyloid filaments in the Biondi bodies of ependymal cells
Acta Neuropathologica 148(1):60DOI: 10.1007/s00401-024-02807-w
PMID: 39503754
PMCID: PMC11541264
Date of Paper: 06/11/2024
Division: NeurobiologyColussi A., Almeida-Souza L., McMahon H.T.
A single particle analysis method for detecting membrane remodelling and curvature sensing
Journal of Cell Science :jcs.263533DOI: 10.1242/jcs.263533
PMID: 39324332
PMCID: PMC11574359
Date of Paper: 01/11/2024
Division: NeurobiologyWatteyne J., Chudinova A., Ripoll-Sánchez L., Schafer W.R., Beets I.
Neuropeptide signaling network of Caenorhabditis elegans: from structure to behavior
Genetics 228(3):iyae141DOI: 10.1093/genetics/iyae141
PMID: 39344922
PMCID: PMC11538413
Date of Paper: 01/11/2024
Division: Neurobiologyde la Rosa-Trevin J.M., Sharov G., Fleischmann S., Morado D., Bollinger J.C., Miller D.J., Terry D.S., Blanchard S.C., Fernandez I.S., Carroni M.
EMhub: a web platform for data management and on-the-fly processing in scientific facilities
Acta crystallographica. Section D, Structural BiologyDOI: 10.1107/S2059798324009471
PMID: 39373194
PMCID:
Date of Paper: 01/11/2024
Division: Facilities (EM)Gong G.Q., Masson G.R., Lee W.J., Dickson J.M.J., Kendall J.D., Rathinaswamy M.K., Buchanan C.M., Middleditch M., Owen B., Spicer J.A., Rewcastle G.W., Denny W.A., Burke J.E., Shepherd P.R., Williams R.L., Flanagan J.U.
ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding
The Biochemical Journal :BCJ20240479DOI: 10.1042/bcj20240479
PMID: 39485310
PMCID:
Date of Paper: 01/11/2024
Division: Protein & Nucleic Acid ChemistryLou F., Zhou W., Tunc-Ozdemir M., Yang J., Velazhahan V., Tate C.G., Jones A.M.
VPS26 Moonlights as a β-Arrestin-like Adapter for a 7-Transmembrane RGS Protein in Arabidopsis thaliana
BiochemistryDOI: 10.1021/acs.biochem.4c00361
PMID: 39467170
PMCID:
Date of Paper: 28/10/2024
Division: Structural StudiesLeventhal S.S., Bisom T., Clift D., Rao D., Meade-White K., Shaia C., Murray J., Mihalakakos E.A., Hinkley T., Reynolds S.J., Best S.M., Erasmus J.H., James L.C., Feldmann H., Hawman D.W.
Antibodies targeting the Crimean-Congo Hemorrhagic Fever Virus nucleoprotein protect via TRIM21
Nature Communications 15(1):9236DOI: 10.1038/s41467-024-53362-7
PMID: 39455551
PMCID: PMC11511847
Date of Paper: 25/10/2024
Division: Protein & Nucleic Acid ChemistryAndrini O., Ben Soussia I., Tardy P., Walker D.S., Peña-Varas C., Ramírez D., Gendrel M., Mercier M., El Mouridi S., Leclercq-Blondel A., González W., Schafer W.R., Jospin M., Boulin T.
Constitutive sodium permeability in a C. elegans two-pore domain potassium channel
Proceedings of the National Academy of Sciences of the United States of America 121(43):e2400650121DOI: 10.1073/pnas.2400650121
PMID: 39405352
PMCID: PMC11513965
Date of Paper: 15/10/2024
Division: NeurobiologyVazquez-Fernandez E., Yang J., Zhang Z., Andreeva A.E., Emsley P., Barford D.
A comparative study of the cryo-EM structures of Saccharomyces cerevisiae and human anaphase-promoting complex/cyclosome (APC/C)
Elife 13:RP100821DOI: 10.7554/elife.100821
PMID: 39401078
PMCID: MC11473103
Date of Paper: 14/10/2024
Division: Structural StudiesManning L.K., Winkenwerder E., Baskind L., Eager K.L.M., Willet C.E., Porebski B., O'Rourke B.A., Tammen I., Gimeno M., Pinczowski P.
A novel missense variant in the <i>RELN</i> gene in sheep with lissencephaly and cerebellar hypoplasia
Veterinary Pathology :3009858241283501DOI: 10.1177/03009858241283501
PMID: 39394905
PMCID:
Date of Paper: 12/10/2024
Division: Protein & Nucleic Acid ChemistryGentile F., Emdin M., Passino C., Montuoro S., Tognini P., Floras J.S., O'Neill J., Giannoni A.
The chronobiology of human heart failure: clinical implications and therapeutic opportunities
Heart Failure ReviewsDOI: 10.1007/s10741-024-10447-1
PMID: 39392534
PMCID:
Date of Paper: 11/10/2024
Division: Cell BiologyShaib A.H., Chouaib A.A., Chowdhury R., Altendorf J., Mihaylov D., Zhang C., Krah D., Imani V., Spencer R.K.W., Georgiev S.V., Mougios N., Monga M., Reshetniak S., Mimoso T., Chen H., Fatehbasharzad P., Crzan D., Saal K.A., Alawieh M.M., Alawar N., Eilts J., Kang J., Soleimani A., Müller M., Pape C., Alvarez L., Trenkwalder C., Mollenhauer B., Outeiro T.F., Köster S., Preobraschenski J., Becherer U., Moser T., Boyden E.S., Aricescu A.R., Sauer M., Opazo F., Rizzoli S.O.
One-step nanoscale expansion microscopy reveals individual protein shapes
Nature BiotechnologyDOI: 10.1038/s41587-024-02431-9
PMID: 39385007
PMCID:
Date of Paper: 09/10/2024
Division: NeurobiologyHochheiser I.V., Geyer M.
Insights into reproduction-regulating NOD-like receptors
Nature Structural & Molecular BiologyDOI: 10.1038/s41594-024-01383-7
PMID: 39333373
PMCID:
Date of Paper: 08/10/2024
Division: Structural StudiesRai S, Szaruga M, Pitera AP, Bertolotti A.
Integrated stress response activator halofuginone protects mice from diabetes-like phenotypes
Journal of Cell Biology Oct 7;223(10):e202405175.DOI: 10.1083/jcb.202405175.
PMID: 39150520
PMCID: PMC11329777
Date of Paper: 07/10/2024
Division: NeurobiologyCrespillo-Casado A., Pothukuchi P., Naydenova K., Yip M.C.J., Young J.M., Boulanger J., Dharamdasani V., Harper C., Hammoudi P.M., Otten E.G., Boyle K., Gogoi M., Malik H.S., Randow F.
Recognition of phylogenetically diverse pathogens through enzymatically amplified recruitment of RNF213
EMBO Reports 25(11):4979-5005DOI: 10.1038/s44319-024-00280-w
PMID: 39375464
PMCID: PMC11549300
Date of Paper: 07/10/2024
Division: Protein & Nucleic Acid ChemistryPospisil D.A., Aragon M.J., Dorkenwald S., Matsliah A., Sterling A.R., Schlegel P., Yu S.C., McKellar C.E., Costa M., Eichler K., Jefferis G.S.X.E., Murthy M., Pillow J.W.
The fly connectome reveals a path to the effectome
Nature 634(8032):201-209DOI: 10.1038/s41586-024-07982-0
PMID: 39358526
PMCID: PMC11446844
Date of Paper: 02/10/2024
Division: NeurobiologyDorkenwald S., Matsliah A., Sterling A.R., Schlegel P., Yu S.C., McKellar C.E., Lin A., Costa M., Eichler K., Yin Y., Silversmith W., Schneider-Mizell C., Jordan C.S., Brittain D., Halageri A., Kuehner K., Ogedengbe O., Morey R., Gager J., Kruk K., Perlman E., Yang R., Deutsch D., Bland D., Sorek M., Lu R., Macrina T., Lee K., Bae J.A., Mu S., Nehoran B., Mitchell E., Popovych S., Wu J., Jia Z., Castro M.A., Kemnitz N., Ih D., Bates A.S., Eckstein N., Funke J., Collman F., Bock D.D., Jefferis G.S.X.E., Seung H.S., Murthy M.; FlyWire Consortium.
Neuronal wiring diagram of an adult brain
Nature 634(8032):124-138DOI: 10.1038/s41586-024-07558-y
PMID: 39358518
PMCID: PMC11446842
Date of Paper: 02/10/2024
Division: Neurobiology
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