Heber S., McClintock M. A., Simon B., Mehtab E, Lapouge K., Hennig J., Bullock S. L., Ephrussi A.
Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport
Nature Structural & Molecular BiologyDOI: 10.1038/s41594-024-01212-x
PMID: 38297086
PMCID:
Date of Paper: 30/01/2024
Division: Cell BiologyGhanim G. E., Sekne Z., Balch S., van Roon A. M, Nguyen T. H. D.
2.7 Å cryo-EM structure of human telomerase H/ACA ribonucleoprotein
Nature Communications 15(1):746DOI: 10.1038/s41467-024-45002-x
PMID: 38272871
PMCID: PMC10811338
Date of Paper: 25/01/2024
Division: Structural StudiesTian R., Rehm F B. H, Czernecki D., Gu Y., Zürcher J. F., Liu K. C., Chin J.W.
Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli
Science 383(6681):421-426DOI: 10.1126/science.adk1281
PMID: 38271510
PMCID:
Date of Paper: 25/01/2024
Division: Protein & Nucleic Acid ChemistryMcRae E. K. S., Wan C. J .K., Kristoffersen E. L., Hansen K., Gianni E., Gallego I., Curran J. F., Attwater J., Holliger P., Andersen E. S.
Cryo-EM structure and functional landscape of an RNA polymerase ribozyme
Proceedings of the National Academy of Sciences of the United States of America 21(3):e2313332121DOI: 10.1073/pnas.2313332121
PMID: 38207080
PMCID: PMC10801858
Date of Paper: 11/01/2024
Division: Protein & Nucleic Acid ChemistrySale J. E., Stoddard B. L.
Fifty years of Nucleic Acids Research
Nucleic Acids Research 52(1): 1–3.DOI: 10.1093/nar/gkad1156
PMID: 38178306
PMCID: PMC10783492
Date of Paper: 11/01/2024
Division: Protein & Nucleic Acid ChemistryDunkelmann D. L., Piedrafita C., Dickson A., Liu K. C., Elliott T. S., Fiedler M., Bellini D., Zhou A., Cervettini D., Chin J.
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism
Nature 10.1038/s41586-023-06897-6DOI: 10.1038/s41586-023-06897-6
PMID: 38200312
PMCID: PMC10794150
Date of Paper: 10/01/2024
Division: Protein & Nucleic Acid ChemistryVollmar M., Nicholls R., Antonyuk S.
Current trends in macromolecular model refinement and validation
Acta crystallographica 80(Pt 1):1-3DOI: 10.1107/s2059798323010823
PMID: 38127063
PMCID: PMC10833345
Date of Paper: 01/01/2024
Division: Structural StudiesMellor C., Nassar J., Šviković S., Sale J. E.
PRIMPOL ensures robust handoff between on-the-fly and post-replicative DNA lesion bypass
Nucleic Acids Research 52(1):243-258DOI: doi.org/10.1093/nar/gkad1054
PMID: 37971291
PMCID: PMC10783524
Date of Paper: 01/01/2024
Division: Protein & Nucleic Acid ChemistryNeidhardt L., Cloots E., Friemel N., Weiss C. A. M., Harding H. P., McLaughlin S. H., Janssens S., Ron D.
The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells
The EMBO JournalDOI: doi.org/10.1038/s44318-023-00014-z
PMID: 38177498
PMCID:
Date of Paper: 18/12/2023
Division: Protein & Nucleic Acid ChemistryTetter S., Arseni D., Murzin A. G., Buhidma Y., Peak-Chew S. Y., Garringer H. J. Newell K. L., Vidal R., Apostolova L. G., Lashley T., Ghetti B., Ryskeldi-Falcon B.
TAF15 amyloid filaments in frontotemporal lobar degeneration
Nature, 625(7994):345-351DOI: 10.1038/s41586-023-06801-2
PMID: 38057661
PMCID: PMC10781619
Date of Paper: 06/12/2023
Division: NeurobiologyDonnelly C. M., Stewart M., Roby J. A., Sundaramoorthy V., Forwood J. K.
Structural Determination of the Australian Bat Lyssavirus Nucleoprotein and Phosphoprotein Complex
Viruses 16(1):33DOI: 10.3390/v16010033
PMID: 38229694
PMCID: PMC7615531
Date of Paper: 01/12/2023
Division: Structural StudiesLövestam S,. Li D., Wagstaff J. L., Kotecha A., Kimanius D., McLaughlin S. H., Murzin A. G., Freund S. M. V, Goedert M., Scheres S. H. W.
Disease-specific tau filaments assemble via polymorphic intermediates
Nature 625(7993):119-125DOI: 10.1038/s41586-023-06788-w
PMID: 38030728
PMCID: PMC10764278
Date of Paper: 29/11/2023
Division: Structural StudiesDrehmann P., Milanos S., Schaefer N., Kasaragod V., Herterich S, Holzbach-Eberle U., Harvey R. J.
Dual role of dysfunctional Asc-1 transporter in distinct human pathologies - human startle disease and developmental delay
eNeuro 0263-23.2023.DOI: 10.1523/ENEURO.0263-23.2023
PMID: 37903619
PMCID: PMC10668224
Date of Paper: 16/11/2023
Division: NeurobiologyLin Z., Green E. W., Webster S. G., Hastings M. H., Wilcockson D. C., Kyriacou C. P.
The circadian clock gene bmal1 is necessary for co-ordinated circatidal rhythms in the marine isopod Eurydice pulchra (Leach)
Plos Genetics 19(11):e1011047DOI: 10.1371/journal.pgen.1011047
PMID: 37967082
PMCID: PMC10651029
Date of Paper: 15/11/2023
Division: NeurobiologyKasaragod V. B., Malinauskas T., Wahid A. A., Lengyel J., Knoflach F., Hardwick S. W., Jones C. F., Chen W. N., Lucas X., El Omari K., Chirgadze D. Y., Aricescu A. R., Cecere G., Hernandez M. C., Miller P. S.
The molecular basis of drug selectivity for α5 subunit-containing GABA(A) receptors
Nature Structural & Molecular Biology 30(12): 1936–1946.DOI: 10.1038/s41594-023-01133-1
PMID: 37903907
PMCID: PMC10716045
Date of Paper: 30/10/2023
Division: NeurobiologyMadan V., Albacete-Albacete L., Jin L., Scaturro P., Watson J. L., Muschalik N., Begum F., Boulanger J., Bauer K., Kiebler M. A., Derivery E., Bullock S. L
HEATR5B associates with dynein-dynactin and promotes motility of AP1-bound endosomal membranes
The EMBO Journal 42(23):e114473DOI: 10.15252/embj.2023114473
PMID: 37872872
PMCID: PMC10690479
Date of Paper: 24/10/2023
Division: Cell BiologyCanon L., Kikuti C., Planelles-Herrero V. J., Lin T., Mayeux F., Sirkia H., Lee Y. I., Heidsieck L., Velikovsky L., David A., Liu X., Moussaoui D., Forest E., Höök P., Petersen K. J., Morgan T. E., Di Cicco A., Sirés-Campos J., Derivery E., Lévy D., Delevoye C., Sweeney H. L., Houdusse A.
How myosin VI traps its off-state, is activated and dimerizes
Nature Communications 14(1):6732DOI: 10.1038/s41467-023-42376-2
PMID: 37872146
PMCID: PMC10593786
Date of Paper: 23/10/2023
Division: Cell BiologyWatson JL, Seinkmane E, Styles CT, Mihut A, Krüger LK, McNally KE, Planelles-Herrero VJ, Dudek M, McCall PM, Barbiero S, Vanden Oever M, Peak-Chew SY, Porebski BT, Zeng A, Rzechorzek NM, Wong DCS, Beale AD, Stangherlin A, Riggi M, Iwasa J, Morf J, Miliotis C, Guna A, Inglis AJ, Brugués J, Voorhees RM, Chambers JE, Meng QJ, O'Neill JS, Edgar RS, Derivery E.
Macromolecular condensation buffers intracellular water potential
Nature 623(7988):842-852DOI: 10.1038/s41586-023-06626-z
PMID: 37853127
PMCID: PMC10665201
Date of Paper: 18/10/2023
Division: Cell BiologySanford S. A. I., Miller L. V. C, Vaysburd M., Keeling S., Tuck B. J., Clark J., Neumann M., Syanda V., James L. C., McEwan W. A.
The type-I interferon response potentiates seeded tau aggregation and exacerbates tau pathology
Alzheimer's & Dementia : the Journal of the Alzheimer's AssociationDOI: 10.1002/alz.13493
PMID: 37849026
PMCID:
Date of Paper: 17/10/2023
Division: Protein & Nucleic Acid ChemistryPorebski B. T., Balmforth M., Browne G. Riley A., Jamali K., Fürst M. J. L.J., Velic M., Buchanan A., Minter R., Vaughan T, Holliger P.
Rapid discovery of high-affinity antibodies via massively parallel sequencing, ribosome display and affinity screening
Nature Biomedical EngineeringDOI: 10.1038/s41551-023-01093-3
PMID: 37814006
PMCID:
Date of Paper: 09/10/2023
Division: Protein & Nucleic Acid ChemistrySchweighauser M., Murzin A. G., Macdonald J., Lavenir I., Crowther R. A., Scheres S. H. W., Goedert M.
Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau
Acta Neuropathologica Communications 11(1):160DOI: 10.1186/s40478-023-01658-y
PMID: 37798679
PMCID: PMC10552433
Date of Paper: 05/10/2023
Division: Structural StudiesZaiss D. M. W., Pearce E. J., Artis D., McKenzie A. N. J., Klose C. S. N.
Cooperation of ILC2s and T(H)2 cells in the expulsion of intestinal helminth parasites
Nature reviews. ImmunologyDOI: 10.1038/s41577-023-00942-1
PMID: 37798539
PMCID:
Date of Paper: 05/10/2023
Division: Protein & Nucleic Acid ChemistryWilliams S. L, Casas-Delucchi C. S., Raguseo F., Guneri D., Li Y., Minamino M., Fletcher E. E., Yeeles J. T., Keyser U. F, Waller Z. A., Di Antonio M., Coster G.
Replication-induced DNA secondary structures drive fork uncoupling and breakage
The EMBO Journal 42(22):e114334DOI: 10.15252/embj.2023114334
PMID: 37781931
PMCID: PMC10646557
Date of Paper: 02/10/2023
Division: Protein & Nucleic Acid ChemistryWilliams S. L., Casas-Delucchi C. S., Raguseo F., Guneri D., Li Y., Minamino M., Fletcher E. E., Yeeles JT ., Keyser U. F., Waller Z. A., Di Antonio M., Coster G.
Replication-induced DNA secondary structures drive fork uncoupling and breakage
The EMBO Journal 42(22):e114334DOI: 10.15252/embj.2023114334
PMID: 37781931
PMCID: PMC10646557
Date of Paper: 02/10/2023
Division: Protein & Nucleic Acid ChemistryChiaradia I., Imaz-Rosshandler I., Nilges B. S., Boulanger J., Pellegrini L., Das R., Kashikar N. D., Lancaster M. A.
Tissue morphology influences the temporal program of human brain organoid development
Cell Stem Cell 30(10):1351-1367.e10DOI: 10.1016/j.stem.2023.09.003
PMID: 37802039
PMCID:
Date of Paper: 01/10/2023
Division: Cell Biology