Xia Y., Sonneville R., Jenkyn-Bedford M., Ji L, Alabert C., Hong Y., Yeeles J. T. P., Labib K. P. M.
DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans
Science 381(6664):eadi4932DOI: 10.1126/science.adi4932
PMID: 37590372
PMCID: PMC7615117
Date of Paper: 22/09/2023
Division: Protein & Nucleic Acid ChemistryBeets I., Zels S., Vandewyer E., Demeulemeester J., Caers J., Baytemur E., Courtney A., Golinelli L., Hasakioğulları İ., Schafer W. R., Vértes P. E., Mirabeau O., Schoofs L.
System-wide mapping of peptide-GPCR interactions in C. elegans
Cell Reports 31.08.2023DOI: 10.1016/j.celrep.2023.113058
PMID: 37656621
PMCID: PMC7615250
Date of Paper: 31/08/2023
Division: NeurobiologyAbsmeier E., Chandrasekaran V., O'Reilly F. J., Stowell J. A. W., Rappsilber J., Passmore L. A..
Specific recognition and ubiquitination of translating ribosomes by mammalian CCR4-NOT
Nature Structural & Molecular Biology 30(9):1314-1322DOI: 30(9):1314-1322
PMID: 37653243
PMCID: PMC7615087
Date of Paper: 31/08/2023
Division: Structural StudiesTajima S., Kim Y. S., Fukuda M., Jo Y., Wang P. Y., Paggi J. M., Inoue M., Byrne E. F. X., Kishi K. E., Nakamura S., Ramakrishnan C., Takaramoto S., Nagata T., Konno M., Sugiura M., Katayama K., Matsui T. E., Yamashita K., Kim S., Ikeda H., Kim J., Kandori H., Dror R. O., Inoue K., Deisseroth K., Kato H. E.
Structural basis for ion selectivity in potassium-selective channelrhodopsins
Cell 186(20):4325-4344.e26DOI: 10.1016/j.cell.2023.08.009
PMID: 37652010
PMCID: PMC7615185
Date of Paper: 30/08/2023
Division: Structural StudiesHu H., van Roon A. M., Ghanim G. E., Ahsan B., Oluwole A. O., Peak-Chew S. Y., Robinson C. V., Nguyen T. H. D.
Structural basis of telomeric nucleosome recognition by shelterin factor TRF1
Science Advances 9(34):eadi4148DOI: 10.1126/sciadv.adi4148
PMID: 37624885
PMCID: PMC10456876
Date of Paper: 25/08/2023
Division: Structural StudiesCiofani J. L., Han D., Allahwala U. K., Woolf B., Gill D., Bhindi R.
Lipids, Blood Pressure, and Diabetes Mellitus on Risk of Cardiovascular Diseases in East Asians: A Mendelian Randomization Study
The American Journal of Cardiology 205:329-337DOI: 10.1016/j.amjcard.2023.08.007
PMID: 37633070
PMCID: PMC7615095
Date of Paper: 24/08/2023
Division: NeurobiologyDe Malmazet D, Tripodi M.Current
Collicular circuits supporting the perceptual, motor and cognitive demands of ethological environmentsde
Current Opinion in Neurobiology 82:102773DOI: 10.1016/j.conb.2023.102773
PMID: 37619424
PMCID:
Date of Paper: 22/08/2023
Division: NeurobiologyRichardson L, Wilcockson SG, Guglielmi L, Hill CS.
Context-dependent TGFβ family signalling in cell fate regulation
Nature reviews. Molecular Cell Biology 24(12):876-894DOI: 10.1038/s41580-023-00638-3
PMID: 37596501
PMCID:
Date of Paper: 18/08/2023
Division: Cell BiologyWarrier V, Stauffer EM, Huang QQ, Wigdor EM, Slob EAW, Seidlitz J, Ronan L, Valk SL, Mallard TT, Grotzinger AD, Romero-Garcia R, Baron-Cohen S, Geschwind DH, Lancaster MA, Murray GK, Gandal MJ, Alexander-Bloch A, Won H, Martin HC, Bullmore ET, Bethlehem RAI.
Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes
Nature Genetics 55(9):1483-1493DOI: 10.1038/s41588-023-01475-y
PMID: 37592024
PMCID: PMC10600728
Date of Paper: 17/08/2023
Division: Cell BiologyBona N., Crossan G. P.
Fanconi anemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mouse development
Nature Structural & Molecular Biology 30(10):1434-1445DOI: 30(10):1434-1445
PMID: 37580626
PMCID: PMC10584689
Date of Paper: 14/08/2023
Division: Protein & Nucleic Acid ChemistryBeale A. D, Hayter E. A, Crosby P., Valekunja U. K., Edgar R. S., Chesham J. E., Maywood E. S., Labeed F. H., Reddy A. B., Wright K. P. Jr, Lilley K. S., Bechtold D. A., Hastings M. H., O'Neill J. S.
Mechanisms and physiological function of daily haemoglobin oxidation rhythms in red blood cells
The EMBO Journal 42(19):e114164DOI: 10.15252/embj.2023114164
PMID: 37554073
PMCID: PMC10548169
Date of Paper: 09/08/2023
Division: Cell BiologyRocha J. J., Jayaram S. A., Stevens T. J., Muschalik N., Shah R. D., Emran S., Robles C., Freeman M., Munro S.
Functional unknomics: Systematic screening of conserved genes of unknown function
Plos Biology 21(8):e3002222DOI: doi.org/10.1371/journal.pbio.3002222
PMID: 37552676
PMCID: PMC10409296
Date of Paper: 08/08/2023
Division: Cell BiologyArseni D., Chen R., Murzin A. G., Peak-Chew S. Y., Garringer H. J., Newell K. L., Kametani F., Robinson A. C., Vidal R., Ghetti B., Hasegawa M., Ryskeldi-Falcon B.
TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP
Nature 620(7975):898-903DOI: 10.1038/s41586-023-06405-w
PMID: 37532939
PMCID: PMC10447236
Date of Paper: 02/08/2023
Division: NeurobiologySuskiewicz M. J., Munnur D., Strømland Ø., Yang J. C., Easton L. E., Chatrin C., Zhu K., Baretić D., Goffinont S., Schuller M., Wu W. F., Elkins J. M., Ahel D., Sanyal S., Neuhaus D., Ahel I.
Updated protein domain annotation of the PARP protein family sheds new light on biological function
Nucleic Acids Research 51(15):8217-8236DOI: 10.1093/nar/gkad514
PMID: 37326024
PMCID: PMC10450202
Date of Paper: 01/08/2023
Division: Structural StudiesSchofield P., Taylor A. I., Rihon J., Peña Martinez C. D., Zinn S., Mattelaer C. A., Jackson J., Dhaliwal G., Schepers G., Herdewijn P., Lescrinier E., Christ D., Holliger P.
Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif
Nucleic Acids Research 51(15):7736-7748DOI: 10.1093/nar/gkad592
PMID: 37439359
PMCID: PMC10450178
Date of Paper: 01/08/2023
Division: Protein & Nucleic Acid ChemistryHöpfler M, Hegde R. S.
Control of mRNA fate by its encoded nascent polypeptide
Molecular Cell 83(16):2840-2855DOI: 10.1016/j.molcel.2023.07.014
PMID: 37595554
PMCID: PMC10501990
Date of Paper: 01/08/2023
Division: Cell BiologyOzturk S. F., Sasselov D. D., Sutherland J. D.
The central dogma of biological homochirality: How does chiral information propagate in a prebiotic network?
The Journal of Chemical Physics 159(6):061102DOI: 10.1063/5.0156527
PMID: 37551802
PMCID:
Date of Paper: 01/08/2023
Division: Protein & Nucleic Acid ChemistryDendooven T., Zhang Z., Yang J., McLaughlin S. H., Schwab J., Scheres S. H. W., Yatskevich S., Barford D.
Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere
Science Advances 9(30):eadg7480DOI: doi.org/10.1126/sciadv.adg7480
PMID: 37506202
PMCID: PMC10381965
Date of Paper: 28/07/2023
Division: Structural StudiesJones M. L, Aria V., Baris Y., Yeeles J. T. P.
How Pol α-primase is targeted to replisomes to prime eukaryotic DNA replication
Molecular Cell 83(16):2911-2924.e16DOI: 10.1016/j.molcel.2023.06.035
PMID: 37506699
PMCID: PMC10501992
Date of Paper: 27/07/2023
Division: Protein & Nucleic Acid ChemistryDe-Souza E. A., Thompson M. A., Taylor R. C
Olfactory chemosensation extends lifespan through TGF-β signaling and UPR activation
Nature Aging 3(8):938-947DOI: 10.1038/s43587-023-00467-1
PMID: 37500972
PMCID: MC10432268
Date of Paper: 27/07/2023
Division: NeurobiologyServettini I., Talani G., Megaro A., Setzu M. D., Biggio F., Briffa M., Guglielmi L., Savalli N., Binda F., Delicata F., Bru-Mercier G., Vassallo N., Maglione V., Cauchi R. J., Di Pardo A., Collu M., Imbrici P., Catacuzzeno L, D'Adamo M. C., Olcese R., Pessia M.
An activator of voltage-gated K(+) channels Kv1.1 as a therapeutic candidate for episodic ataxia type 1
Proceedings of the National Academy of Sciences of the United States of America 120(31):e2207978120DOI: 10.1073/pnas.2207978120
PMID: 37487086
PMCID: PMC10401004
Date of Paper: 24/07/2023
Division: Cell BiologyYagita Y., Zavodszky E., Peak-Chew S. Y., Hegde R. S.
Mechanism of orphan subunit recognition during assembly quality control
Cell 186(16):3443-3459.e24DOI: 10.1016/j.cell.2023.06.016
PMID: 37480851
PMCID: PMC10501995
Date of Paper: 21/07/2023
Division: Cell BiologyBeattie A.T., Dunkelmann D. L., Chin J. W.
Quintuply orthogonal pyrrolysyl-tRNA synthetase/tRNA(Pyl) pairs
Nature Chemistry 15(7):948-959DOI: doi.org/10.1038/s41557-023-01232-y
PMID: 37322102
PMCID:
Date of Paper: 15/07/2023
Division: Protein & Nucleic Acid ChemistryRitson D. J., Sutherland J. D.
Thiophosphate photochemistry enables prebiotic access to sugars and terpenoid precursors
Nature Chemistry 15(10):1470-1477DOI: 10.1038/s41557-023-01251-9
PMID: 37443293
PMCID: PMC10533393
Date of Paper: 13/07/2023
Division: Protein & Nucleic Acid ChemistryTarutani A., Lövestam S., Zhang X., Kotecha A., Robinson A. C., Mann D.M. A., Saito Y., Murayama S., Tomita T., Goedert M., Scheres S. H. W., Hasegawa M.
Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration
FEBS Open bio 13(8):1394-1404DOI: 10.1002/2211-5463.13657
PMID: 37337995
PMCID: PMC10392052
Date of Paper: 07/07/2023
Division: Structural Studies
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