MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Projects

Applications for 2026 LMB PhD places  are now open.

Please click here to apply. Deadline is 2 December 2025

Matteo Allegretti

The macromolecular basis of nuclear reshaping in humans

Radu Aricescu

The molecular architecture of neurotransmission

Diana Arseni

Lysosomal TMEM106B in brain ageing and disease

Buzz Baum

Inferring a cell’s structure from its genes

Anne Bertolotti

Structure-function analysis of stress signaling.

Tanmay Bharat

Towards molecular-resolution snapshots of tissues

Simon Bullock

Deconstructing and reconstructing mRNA transport

Andrew Carter

How pathogens hijack dynein/dynactin

Juliette Fedry

Visualizing cellular proteostasis

Ingo Greger

Glutamate receptor structure and synaptic transmission

Philipp Holliger

Replicating RNA with RNA

Gregory Jefferis

Connectomics across sexes, species and states

Madeline Lancaster

How does the human brain get so big?

Jan Löwe

Molecular mechanisms of SMC Complexes

Kate McDole

How the embryo gets its shape

Harvey McMahon

Protein aggregates and neurodegeneration

Lori Passmore

Mechanistic insight into macromolecular machines.

Felix Randow

LPS ubiquitylation and innate immunity

Wes Robertson

Synthetic genomics of recoded gut bacteria

Benjamin Ryskeldi-Falcon

Pathological protein assembly in neurodegenerative diseases

Julian Sale

ecDNA replication

William Schafer

Neural circuits and behaviour in octopus hatchlings

Sjors Scheres

Cryo-EM image processing (possibly of amyloids)

Marta Shahbazi

Aneuploiody in the human embryo

Marco Tripodi

Transforming thoughts into actions

Sven Truckenbrodt

Molecular brain mapping of biological computation

Ana Tufegdžić Vidaković

Discovering the “missing” transcription mechanisms

Suyang Zhang

Mechanism of transcription-coupled splicing

Marta Zlatic

Circuit basis of learning and action-selection

The LMB exceptionally considers applications for research-only MPhil students provided they obtain their own competitive funding and have the support of a group leader in the Laboratory. For information contact phdenq.