MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Projects

Applications for the LMB PhD programme are now open.

Deadline 3rd December 2024. Apply here.

Radu Aricescu

The molecular architecture of neurotransmission

Diana Arseni

Lysosomal TMEM106B in brain ageing and disease

David Barford

Cryo-EM study of the human kinetochore

Anne Bertolotti

Boosting protein quality control

Albert Cardona

Brains and sex

Jason Chin

Synthetic Biology

Emmanuel Derivery

Illuminating the polarized endosomal pathway

Joe Greener

Making biomolecules move with machine learning

Ingo Greger

AMPA receptor structure and function

Philipp Holliger

Replicating RNA with RNA

Leo James

TRIM21 degradation of viruses and aggregates

Gregory Jefferis

Neural Circuits for Sex and Memory in the Fly

Joergen Kornfeld

From connectomes to behaviour

Roni Levin Konigsberg

How phagocytic cells clear pathogenic materials

James Manton

Engineering fluorescent proteins for live and super-resolution microscopy

Kate McDole

How the embryo gets its shape

Andrew McKenzie

Neuro-immune interactions in tissue neighbourhoods

Michel Goedert & Sjors Scheres

Cryo-EM studies of amyloids in neurodegenerative diseases

Sean Munro

How the Golgi works

Kelly Nguyen

Visualisation of yeast telomerase complexes

John O'Neill

In vitro reconstitution of the circadian clock

Lori Passmore

Mechanistic insight into macromolecular machines

Lalita Ramakrishnan

Cell biology underlying tuberculosis

Felix Randow

LPS ubiquitylation and innate immunity

Wes Robertson

Synthetic genomics in gut bacteria

Noe Rodriguez

Mapping neuroimmune interactions at mucosal sites

Benjamin Ryskeldi-Falcon

Pathological protein assembly in neurodegenerative diseases

Sjors Scheres

Computational developments for Structural Biology

Chris Tate

Cryo-EM structures of GPCRs from pathogenic fungi

Ana Tufegdžić Vidaković

Discovering the “missing” transcription mechanisms

Joseph Yeeles

Structures and mechanisms of the human replisome

Suyang Zhang

Mechanism of transcription-coupled splicing

Marta Zlatic

Circuit basis of learning and action-selection

Jerome Zurcher

Development of genome synthesis methods for genetic isolation

The LMB exceptionally considers applications for research-only MPhil students provided they obtain their own competitive funding and have the support of a group leader in the Laboratory. For information contact phdenq.