Day 269 of #LMB365 is a photo peering in on a low energy plasma chamber built in the LMB Workshops with Chris Russo from the Structural Studies Division. Plasmas such as these are used to modify the support grids used for imaging proteins in cryoEM
Image365
LMB 365 – Day 268
This image for day 268 of #LMB365 shows the brain and some imaginal discs isolated from a Drosophila larva. Imaginal discs are sacks of cells that will develop into adult structures such as wings, legs and eyes during metamorphosis. The tissue was stained for GFP (green), Wingless (red) as well as DAPI (blue), which marks the nuclei.
LMB 365 – Day 267
LMB scientists will be taking C. elegans worms to Queensgate shopping centre in Peterborough on Saturday 28th September to tell members of the public about how we use worms to study how neurons work and improve our understanding of ageing and disease. On day 267, we see a previous occasion when visitors got to see some of our worms.
LMB 365 – Day 266
This image for day 266 of #LMB365 shows a female mouse relaxing in a ‘Nombrero’. This is just one example of the environmental enrichment provided to LMB mice. The Biological Services Group provides some form of environmental enrichment to all mice as part of their commitment to improving animal welfare. The aim of environmental enrichment is to provide opportunities to express species-specific behaviours. The Nombrero was originally designed to hold wet mashed food, however this little mouse prefers to use it as a comfy bed!
LMB 365 – Day 265
Day 265 of #LMB365 shows the front entrance of the LMB taken at dusk by Conny Yu.
LMB 365 – Day 264
On day 264 of #LMB365 is an image of the structure of the 30S ribosomal subunit. This structure was first published #OTD in 2000 in a landmark paper in Nature by Venki Ramakrishnan and colleagues. The 30S ribosomal subunit has a crucial role in decoding mRNA by monitoring base pairing between the codon on mRNA and the anticodon on transfer RNA. Venki shared the 2009 @Nobel Prize in Chemistry for his work on determining the ribosome structure. Brian T.Wimberly, Ditlev E.Brodersen, William M.Clemons Jr, Robert J.Morgan-Warren, Andrew P.Carter, Clemens Vonrhein, Thomas Hartsch, V.Ramakrishnan. Structure of the 30S ribosomal subunit. Nature 407(6802):327-339, 21 September 2000