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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Image365

LMB 365 – Day 227

Published on 15 August, 2019

It is generally thought that abnormal proteins aggregate, the aggregates get ubiquitinated, and this leads to their degradation by autophagy or the proteasome. Hugh Pelham’s group in Cell Biology has been working on ubiquitination of protein condensates by Nedd4 ubiquitin ligases. These images for day 227 of #LMB365 show that artificial protein condensates (green, left) […]

LMB 365 – Day 226

Published on 14 August, 2019

We have recently purchased a jet washer to help improve the external appearance of the site. On day 226 of #LMB365, Phil Peck from Domestic Services has started to pressure wash the paths around the LMB building. Hopefully it’s not like painting the Forth Railway bridge…

LMB 365 – Day 225

Published on 13 August, 2019

On day 225 of #LMB365 is Fred Sanger who was born #OTD in 1918. He is the only Briton to have been awarded two @Nobel prizes and the only scientist to have been awarded the Nobel Prize for Chemistry twice: in 1958 and 1980. He first developed methods for amino acid sequencing and then pioneered […]

LMB 365 – Day 224

Published on 12 August, 2019

Day 224 of #LMB365 shows the first cruise undertaken by an #LMBee. It enjoyed visiting locations around the Mediterranean including Barcelona, Malta, Sicily and Genoa in the company of Danny Leader. Who knew you could have so much fun with a cuddly bee nicknamed “Barnaby”?

LMB 365 – Day 223

Published on 11 August, 2019

Day 223 of #LMB365 shows Aaron Klug beside an electron microscope at the LMB. Aaron was born #OTD in 1926. He was instrumental in revealing the structures of complex biological molecules, from viruses to tRNA, to chromatin and zinc fingers. His most important contribution to scientific research was his painstaking development of crystallographic electron microscopy. This combines the techniques of electron microscopy and X-ray diffraction to recover three-dimensional structural information from two-dimensional electron micrographs. For this he was the sole recipient of the 1982 @Nobel Prize in Chemistry

LMB 365 – Day 222

Published on 10 August, 2019

On day 222 of #LMB365 is a lovely pyramid orchid that has been blooming in the wildflower areas around the LMB. This one, in the drainage ditch verge, adds a bright pop of colour on the way to work

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