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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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LMB In The News

Genetic coding revamp

Published on 15 February, 2010

“Scientists have developed a new genetic language using a ribosome that can read instructions that are 4 base pairs long, enabling the construction of designer proteins containing a variety of unnatural elements, according to a study published online today (February 14) in Nature… synthetic biologist Jason Chin of the Medical Research Council Laboratory of Molecular […]

A new line of research in the fight against Alzheimer’s disease and dementia

Published on 15 February, 2010

“Etienne-Emile Baulieu’s research team (Inserm research unit 788 “Steroids, neuroprotection et neuroregeneration”), in collaboration with Michel Goedert (who originally characterised the Tau protein in Alzheimer’s disease in 1998) have just identified an interaction between the dysfunctional Tau protein and another protein, FKBP52. Using tools from biochemistry and molecular biology, the researchers established that there was […]

Flash frozen under the electron microscope: Examining the mechanical properties of Alzheimer’s amyloid fibrils

Published on 3 February, 2010

“By using electron microscopic images of flash frozen samples, researchers have now been able to examine the exact structure of Alzheimer’s amyloid fibrils and to assess their mechanical properties. As the team reports in the journal Angewandte Chemie, the fibrils are very stiff — one of the underlying causes of their pathogenicity. Because amyloid fibrils […]

Venki Ramakrishan chosen for ‘Padma Vibhushan’, India’s highest civilian award

Published on 28 January, 2010

“Padma Awards, the country’s highest civilian awards, are conferred in three categories, namely, Padma Vibhushan, Padma Bhushan and Padma Shri… ‘Padma Vibhushan’ is awarded for exceptional and distinguished service. The awards are announced on the occasion of Republic Day every year and are conferred by the President of India at a function held at Rashtrapati […]

Nobel Prize winners visit Downing Street

Published on 20 January, 2010

“British winners of the prestigious Nobel Prize have gathered at Downing Street to celebrate their achievements … Guests included recent winner Venkatraman Ramakrishnan, a structural biologist at the MRC Laboratory of Molecular Biology in Cambridge, who received the 2009 Nobel Prize in Chemistry…” This article is no longer available from the source website: Number10.gov.uk, 18 […]

3D structure of PI3Kdelta: An important drug target for a wide range of diseases

Published on 13 January, 2010

“Intellikine announced today the publication of an article entitled, “The p110delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors,” now available as an advanced online publication at Nature Chemical Biology…The pioneering work was the result of a collaboration led by Roger Williams, Ph.D., Professor in the Laboratory of Molecular Biology at the Medical […]

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