A stormy day over the Cambridge Biomedical Campus and the LMB, captured here for day 326 of #LMB365 by Alexey Murzin. One end of the rainbow is over the new Royal Papworth Hospital.
LMB 365 – Day 326
LMB 365 – Day 325
Day 325 of #LMB365 shows the LMBees being excited by all the new cutting edge techniques presented at the recent Next Generation Biophysics meeting https://www3.mrc-lmb.cam.ac.uk/sites/nextgen/ that brought scientists from academia and industry together to discuss new developments. All the speakers were given their LMBees as a memento of their visit to the LMB. We hope they will all return next year for the next installment
How and why researchers should engage with Parliament
Jonida Tafilaku, a PhD student in Paula da Fonseca’s group in the LMB’s Structural Studies Division, completed a three-month internship with the Parliamentary Office of Science and Technology (POST), as part of UKRI’s Policy Internships Scheme for doctoral students funded by UKRI. Motivated by a desire to share her experience of this scheme, Jonida organised this seminar and invited her supervisor from the internship to talk about POST and its role in Parliament.
LMB 365 – Day 324
This image for day 324 of #LMB365 shows a cryo-EM visualisation of a G protein-coupled receptor reconstituted into a lipid nanodisc and then coupled to beta-arrestin from Chris Tate’s group in the Structural Studies Division
LMB 365 – Day 323
Asymmetric cell division is the process by which one cell gives rise to two daughters that have different fate. Asymmetric cell division is the hallmark of stem cells, which generate all the different cell types in the organism. The Derivery Lab in the Cell Biology Division uses the fruit fly to study the molecular mechanism of asymmetric cell division as it is amenable to imaging and genetic modifications. This image for day 323 of #LMB365 represents the back of the fly (called the notum), where all the cells express a cytoskeleton marker in green, while only the cells dividing asymmetrically express a red marker. These cells form a remarkable aligned array, which will give rise to the mechanosensory bristles on the adult fly.
New insights into the architecture of organelle contact sites, and the sites’ roles in cellular lipid fluxes
By combining fluorescence microscopy and electron tomography, Wanda Kukulski’s lab in Cell Biology Division has visualised protein structures that bridge contact sites between the endoplasmic reticulum and plasma membrane in yeast, in their native environment i.e. within the cell.