From fly connectomics to molecular and cellular mechanisms of cytoplasmic dynein, from genetic code fidelity to the molecular mechanism of trans-translation – the Max Perutz Student Prizes were awarded to a diverse range of PhD research.
Student prizes awarded for outstanding doctoral research
LMB 365 – Day 301
Day 301 of #LMB365 shows the sun setting on the west end of the LMB building. It’s amazing how the building can look at different times of day throughout the year.
LMB 365 – Day 300
CryoEM structures determined by Yorgo Modis’ group show how the innate immune sensor MDA5 recognizes viral RNA by forming filaments. ATP hydrolysis is coupled to structural changes in the filament, which are proposed to promote discrimination between viral and cellular RNAs. Depicted here on day 300 of #LMB365 is a model of an MDA5-dsRNA filament (foreground). A viral dsRNA genome and the endosome that delivered it into the cytosol are shown in the background.
LMB 365 – Day 299
This photo for day 299 of #LMB365 shows some of the LMB’s Domestic Services team celebrating James’ birthday. The LMB has many long-term members of staff and these 3 between them have racked up over 50 years of loyal service.
LMB 365 – Day 298
During the last year, over 4,500 initial crystallisation screens were used at the LMB to test macromolecular samples of interest. Further screens are often required for optimisation purposes. The corresponding trays containing the crystallisation experiments are stored in temperature-controlled rooms as seen here on day 298 of #LMB365.
LMB 365 – Day 297
Day 297 of #LMB365 is a screenshot from our internal “Bee Cam”. It shows our resident beekeeper Geoff putting on a feeder of sugar syrup for the LMB’s bees to build up stores for the winter. The bees have also been treated for mites so hopefully they will be well until next year.