This image for day 188 of #LMB365 was collected by Michael Wozny in Wanda Kukulski’s group in Cell Biology using the ion beam source of a Scanning Electron Microscope (SEM). Clumps of plunge-frozen yeast cells are seen centred within the grid squares of an electron microscope grid. The Focussed Ion Beam (FIB) is used to carefully remove material off the tops and bottoms of these cells to produce thin sections called lamellae that are ~200 nm in thickness. These lamellae are then suitable to be imaged using cryo-electron tomography using the LMB’s Titan Krios microscopes.
LMB 365 – Day 188
LMB 365 – Day 187
PhD students at the LMB are registered with the University of Cambridge, and are therefore automatically members of a college. This photo for day 187 of #LMB365 shows members of Bill Schafer’s lab celebrating the end of another day in the LMB by going to a formal dinner at Homerton College.
LMB 365 – Day 186
Day 186 of #LMB365 shows a common occurrence at the LMB. Our Nobel laureates, on this occasion Venki Ramakrishnan, and others are frequently called upon to be interviewed about their science. More can be found on our YouTube channel at https://www.youtube.com/user/LMBCambridge/
LMB 365 – Day 185
On day 185 of #LMB365, the early morning sunshine casts a reflection of a 1950s ball and spoke model of the alpha-helix peptide chain onto the wall of the library mezzanine. Linus Pauling, of Caltech, beat the MRC Unit in solving this structure and this gave the Cambridge team the urgency to be first in determining the structure of DNA
LMB 365 – Day 184
This photo for day 184 of #LMB365 was taken by Ben Phillips when leaving work at sunset on the summer solstice, when most people had already gone home for the night. Amazing colours and reflections…
LMB 365 – Day 183
This image for day 183 of #LMB365 is the surface of a Drosophila melanogaster embryo showing fluorescent markers of nuclei (magenta) and cell membranes (green) from Yara Sanchez-Corrales in Katja Röper’s group in the Cell Biology Division.