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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > LMB 365 – Day 158

LMB 365 – Day 158

LMB 365 – Day 158

Published on 7 June, 2019

Between the floors of the LMB’s building are full height Interstitial Service Voids (ISVs), which house the ductwork, pipes and services. These ISVs are normally only accessible for maintenance and modifications by the Estates and Facilities team. The team recently ran some “Secret LMB Tours” for the LMB’s students to allow them to see behind the scenes in these areas and this photo for day 158 of #LMB365 was taken while they found out more about how the building functions.

LMB 365 – Day 157

Published on 6 June, 2019

Day 157 of #LMB365 shows an artistic view of a ribosome engineering process created by Zakir Tnimov and Wolfgang Schmied in Jason Chin’s group. This ‘stapled’ ribosome has subunits linked by an RNA hinge and can be evolved for synthetic polymer synthesis in cells.

M. Madan Babu awarded the EMBO Gold Medal

Published on 5 June, 2019

M. Madan Babu, a Group Leader in the LMB’s Structural Studies Division, has been awarded the EMBO Gold Medal for his “fundamental contributions to the field of computational molecular biology”. Madan shares the prize with Paola Picotti at ETH Zurich. The EMBO Gold Medal is awarded annually to scientists under 40 for outstanding contributions to […]

LMB 365 – Day 156

Published on 5 June, 2019

How do cells distinguish normal proteins from defective proteins and selectively get rid of the latter? This is one of the questions Manu Hegde’s lab is trying to answer because problems in getting rid of defective proteins can lead to neurodegeneration. In this microscope image of two cells for day 156 of #LMB365, normal and defective versions of the same protein are visualised in red and green, respectively. The cell keeps the normal protein on the cell surface, where it belongs, but most of the defective protein is found in degradation compartments called lysosomes. How cells know to remove only the defective proteins from the cell surface is being investigated by Eszter Zavodszky in the Hegde lab.

LMB 365 – Day 155

Published on 4 June, 2019

On day 155 of #LMB365 it appears the LMB bees have been busy. This is a honey frame from one of our hives two thirds full and capped over. Once full this can be extracted and the honey bottled ready for use. We hope to have LMB honey available during 2019!

LMB 365 – Day 154

Published on 3 June, 2019

It’s not every day an LMB Group Leader has a significant birthday, so John O’Neill’s group in Cell Biology surprised him with a molecularly crowded Happy Birthday on day 154 of #LMB365.

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