Huping Wang and Manu Hegde, in the LMB’s Cell Biology Division, have found a factor that helps nascent secretory and membrane proteins quickly access the protein translocation machinery when they arrive at the endoplasmic reticulum.
Discovery of a factor that accelerates protein deliveries to the endoplasmic reticulum
Advancing technologies take centre stage at Next Generation Biophysics Symposium
The LMB was delighted to once again host the Next Generation Biophysics where several distinguished speakers discussed cutting-edge biophysical techniques.
Cryo-ET reveals new molecular insights into tau pathology in Alzheimer’s disease
Benjamin Ryskeldi-Falcon’s group in the LMB’s Neurobiology Division have used cryo-ET to discover that tau filaments are tethered to the membranes of extracellular vesicles in Alzheimer’s disease. These findings introduce membrane tethering of amyloid filaments as a potential target to interfere with their accumulation in disease.
Why do infectious and autoimmune diseases result in joint pain or inflammation?
Tetsuo Hasegawa and Menna Clatworthy, in the University of Cambridge’s Molecular Immunity Unit house at the LMB, studied a synovial knee joint, finding porous capillaries which allow access by circulating immune stimuli, which is in turn policed by a blood-joint barrier of macrophages and nociceptor neurons.
Top prize for Andrija Sente’s research revealing the diversity within brain receptors
LMB 2018-2023, Ph.D. Student, Postdoctoral Scientist, Neurobiology Congratulations to Andrija Sente who has won top prize in the Science and SciLifeLab Prize for Young Scientists for his research in Radu Aricescu’s group at the LMB. His work uncovered a surprising diversity in the structure of GABAA receptors, which are crucial to the function of the […]
Jason Chin receives honorary doctorate from ETH Zurich
Jason Chin, joint Head of the PNAC Division at the LMB, has been awarded an honorary doctorate by the ETH Zurich.