Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with repeated blows to the head, particularly in relation to contact sports, such as American football and boxing. Understanding of the disease is limited and there is no available treatment. Definitive diagnosis currently depends on examination of the brain after death. Work by Michel Goedert’s group […]
New tau structures may benefit diagnosis and treatment of head injury-associated neurodegeneration
LMB 365 – Day 80
LMB scientists often give talks to explain their research for members of the public. For day 80 of #LMB365 we see Liz Miller contributing to the Cambridge Science Festival and describing how cells police their proteins to make sure that they are assembled correctly
LMB 365 – Day 79
This drawing for day 79 of #LMB365 is by Paul Margiotta #piljammin in the LMB’s Visual Aids team. It is an abstract interpretation of the LMB’s use of X-rays to reveal hitherto undefined protein structures overlaid with the period feel of the film used for this early work.
‘Mini-brains on the move’ that can contract muscle
Researchers in Madeline Lancaster’s group have developed a method of growing cerebral organoids, or mini-brains, that allows longer-term development and showed that these mini-brains can stimulate muscle contraction. More…
LMB 365 – Day 78
LMB scientists are taking part in the Cambridge Science Festival. On day 78 of LMB365 we see some of the new model proteins that visitors made while learning about synthetic biology at the Guildhall on Saturday.
Cerebral organoids at the air-liquid interface generate nerve tracts with functional output
Cerebral organoids, also sometimes called mini-brains or brain organoids, have become an important and useful tool in understanding human brain development and disease. They have the potential to model brain functions, such as information transfer between neurons, but restrictions in their growth have so far limited this. Now, Madeline Lancaster’s group in the LMB’s Cell […]