Electron cryo-microscopy (cryo-EM) is used across the LMB to determine protein structures. Part of the process for data collection involves screening grids in the electron microscope to check the grids have been produced correctly and the samples can be used. Sadly this is not always the case and on day 77 of #LMB365 “Sam” identified that the ice was too thin to be useful. To cheer himself up he wrote his name in the holes of the EM grid by melting the ice with the electron beam.
LMB 365 – Day 77
LMB 365 – Day 76
Day 76 of #LMB365 is an image of synchronous nuclear divisions in the fruit fly embryo captured by David Salvador-Garcia in Simon Bullock’s lab in the LMB’s Cell Biology Division. David is studying how chromosome segregation is co-ordinated by the molecular motor dynein.
LMB 365 – Day 75
On day 75 of #LMB365 we celebrate Daniela Peris @ddanielaperis finishing her PhD viva. During her PhD, Daniela was a member of Gonville and Caius College @caiuscollege, so she was presented with a wall plaque of the College crest. She was also a keen rower for her College (wining superblades in Bumps), and was constantly cold when on the river, so she was given a woolly hat showing the University of Cambridge crest. Daniela was a Milstein Scholar and worked on the in vitro diversification of antibodies using the DT40 chicken cell line.
Architecture of a prominent neurotransmitter receptor involved in memory formation and learning revealed
AMPA receptors are among the most commonly found receptor in the nervous system and play an important role during memory formation and learning. They are composed of four subunits with various possible combinations. Although AMPA receptors act predominantly as heteromeric complexes, structural studies to date have focused on assemblies made from four copies of the […]
LMB 365 – Day 74
Day 74 of #LMB365 is of some hand-painted Russian dolls attempting bench work. They were a gift from Evgeny Zatulovskiy to Rob Kay upon his retirement. Evgeny was a PhD student with Rob on a Herchel Smith Fellowship and is currently a postdoc in San Francisco. The dolls show Rob, David Traynor and Evgeny himself (dolls 2, 3 and 4), then a Dictyostelium fruiting body, migrating slug and amoeba. Obviously, not to scale!
LMB 365 – Day 73
Day 73 of #LMB365 brings you a group photograph of the MRC Council who held their recent meeting here at the LMB. The MRC Council is responsible for advising the MRC Executive Chair and making decisions, as delegated to it by the UKRI Board, on scientific, research and innovation matters.