Recent work carried out by David Komander’s group in the LMB’s Protein and Nucleic Acid Chemistry Division, and published in two separate papers, has provided insight into human disease and the role played by ubiquitination, a process that affects many fundamental cellular processes. Work in David’s group aims to understand the cellular machinery for specific […]
Work on ubiquitination reveals insights into disease
The great coffee breakthrough
In the bright and airy canteen of the MRC Laboratory of Molecular Biology’s new building, Dr Richard Henderson is demonstrating his habit of drawing on saucers. He’s not doodling but rather trying to get across the idea that the canteen, while a place to get a cup of tea or coffee, is also a place […]
David Komander’s Lister Research Prize Lecture
David Komander, from the LMB’s Protein and Nucleic Acid Chemistry Division, will deliver his Lister Prize Lecture, “Specificity in the ubiquitin system”, on Friday 7th June 2013 at 4.00pm. This prestigious award is given annually by The Lister Institute to three young researchers in the UK to support quality research in the biomedical or related […]
Building for the future
As the staff of the MRC Laboratory of Molecular Biology settle into their new building in Cambridge, its director Hugh Pelham explains the challenges of living up to its prestigious past. More…
Insights into spliceosomal activation and molecular pathology of retinitis pigmentosa eye disease
Work published in the journal Structure by Kiyoshi Nagai’s group in the LMB’s Structural Studies Division, has provided further detailed information on the structure and role of proteins at the active site of the spliceosome, and may also help to explain the molecular pathology of the eye disease, retinitis pigmentosa type 13 (RP13). The spliceosome […]
Queen tours ‘Nobel Prize factory’
The Queen has toured a world-leading research institute in Cambridge dubbed the “Nobel Prize factory”. Peering down a powerful microscope to look at tiny mice eggs, the Queen appeared fascinated as scientists explained their work trying to discover why some women trying to conceive produce abnormal eggs. More…