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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > Novel Mechanism for Regulating Inflammation and Cancer Discovered

Novel Mechanism for Regulating Inflammation and Cancer Discovered

Novel Mechanism for Regulating Inflammation and Cancer Discovered

Published on 13 January, 2012

Matthew Freeman’s group in the LMB’s Cell Biology Division have discovered a novel protein, iRhom2, that plays a central role in the signalling pathways that regulate inflammation and cancer. The cytokine protein, TNF, is the primary trigger of inflammation in humans. To function, active TNF must be shed from cells by the protease TACE. TACE […]

Sean Munro Elected as AAAS Fellow

Published on 9 January, 2012

Sean Munro, group leader in the LMB’s Cell Biology Division, has been elected as a Fellow of The American Association for the Advancement of Science (AAAS). Election as a Fellow of AAAS is an honour bestowed upon members by their peers. Fellows are recognized for meritorious efforts to advance science or its applications. Founded in […]

Nobel laureate Venki Ramakrishnan honoured with Knighthood

Published on 3 January, 2012

Dr Venki Ramakrishnan, Joint Head of the LMB’s Structural Studies Division, has been honoured with a knighthood in the New Year Honours List 2012. The award is for services to molecular biology. Venki’s research focuses on the structure and function of the ribosome. This complex structure, found in multiple copies in every living cell, translates […]

Cutting edge chemistry in 2011

Published on 22 December, 2011

“The RNA world hypothesis also got a boost this year with work from Philipp Holliger’s team at the Medical Research Laboratory in Cambridge, UK. The hypothesis, first suggested by Francis Crick in 1968, suggests that life on Earth began with a self-replicating RNA molecule but has remained unproved. Holliger went back…” More…

Is a cure for the common cold on the way?

Published on 21 December, 2011

“BBC science review article looks at recent developments in cold and flu virus research, quoting LMB’s Leo James.” More…

Are the days of incurable diseases really over?

Published on 20 December, 2011

“Are the days of incurable diseases really over? Not quite, when diseases such as tuberculosis are seeing a resurgence, said biologist Ramakrishnan, Joint Head of the Structural Studies Division at the Medical Research Council, Cambridge. He was delivering a lecture on ‘How antibiotics illuminate Ribosome function and vice versa.’” This article is only available in […]

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