New specimen supports, designed by Chris Russo’s group in the LMB’s Structural Studies Division, solve decades-long question on how to use liquid helium in cryo-EM to reduce radiation damage and improve information capture.
A colder frontier: cryo-EM at liquid helium temperatures
Emmanuel Derivery on winning the Hooke Medal, how to manage an inter-disciplinary research group, and the exciting field of protein design
Emmanuel Derivery, Group Leader in the LMB’s Cell Biology Division, speaks to the Journal of Cell Science on the motivations behind his career as a researcher studying fundamental cellular processes, his international collaborations in the field of protein design, and the advice he’d give to scientists looking to start their own research groups. More…
2025 César Milstein Lecture to be delivered by David Pellman
The 2025 César Milstein Lecture titled ‘Mechanisms driving the rapid evolution of genomes’ will be given by David Pellman at 10am (BST) on Thursday 24th April.
Spyros Artavanis-Tsakonas, Iva Greenwald and Gary Struhl share 2025 Canada Gairdner International Award
Artavanis-Tsakonas: LMB 1971-1974, PhD student, PNACGreenwald: LMB 1983-1986, Postdoctoral Visitor, Cell BiologyStruhl: LMB 1976-1982; PhD student; Scientific Staff, Cell Biology The three alumni received the prize for their work on Notch signalling, identifying it as a fundamental cell communication pathway which governs cell fate decisions and, when dysregulated, is implicated in several diseases including neurodegeneration […]
Cytosol-adapted bacterium usurps host defence mechanism to evade LPS ubiquitylation
Felix Randow’s group, in the LMB’s PNAC Division, has identified the mechanism by which cytosol-dwelling Shigella flexneri bacteria use their effector protein IpaH1.4 to avoid LPS ubiquitylation by degrading the host E3 ligase RNF213.
Benjamin Ryskeldi-Falcon awarded The Colworth Medal from the Biochemical Society
Benjamin Ryskeldi-Falcon, Group Leader in the LMB’s Neurobiology Division, has been recognised for his research into the molecular basis of neurodegenerative diseases.