Laura Pellegrini, a postdoc in Madeline Lancaster’s group, has been awarded the 3Rs Prize for her paper investigating cerebrospinal fluid production using brain organoids.
Laura Pellegrini wins 3Rs Prize for the development of a brain barrier organoid
Reprogrammed cells encode for new synthetic polymers and are also resistant to viral infections
Jason Chin and his team, from our PNAC Division, discuss their reprogrammed E.coli cells which are viral resistant and capable of producing entirely synthetic polymers with Roland Pease in BBC Science in Action. More…
Cells reprogrammed for genetically encoded polymer synthesis and viral resistance
Jason Chin’s group, in our PNAC Division, has created cells with a synthetic genome and instructed them to make novel polymers from artificial building blocks for the first time. These new bacteria have also proved resistant to viral infections.
New structures show how auxiliary subunits modulate hippocampal AMPA receptor neurotransmission
AMPA receptors mediate fast excitatory signal transmission and are created from combinations of subunits in a tissue-specific manner. Ingo Greger’s group provides the first visualisations of a hippocampal AMPA receptor involved in memory formation, with two auxiliary subunits.
A new way to mark bacterial invaders for destruction
Ubiquitylation is a process that marks cell-invading pathogens and non-functional organelles for autophagy. Felix Randow’s group has shown that RNF213 catalyses the ubiquitylation of LPS on invading bacteria. This is the first example for ubiquitylation of a non-protein substrate.
Marta Shahbazi on being a mother scientist
As part of a series covering how researchers have been impacted by the COVID-19 pandemic, Science Direct have featured Marta Shahbazi (group leader in our Cell Biology Division) and her experience of juggling being a new group leader and a new mother during lockdown. More…