People infected with SARS-CoV-2 experience a large range in severity of infection. Menna Clatworthy’s group has taken part in the largest study of its type to investigate differences in the immune response that could explain this variation.
How immune responses differ between asymptomatic cases and people with severe COVID-19
First atomic model of human telomerase constructed by electron cryo-microscopy
Telomerase is a vital enzyme which synthesizes telomeric repeats at eukaryotic chromosome ends to compensate for loss generated by incomplete genome replication. Kelly Nguyen’s group has produced the first atomic structure of the complex and revealed histones as novel subunits.
2021 Max Perutz Lecture to be given by David Baker
David Baker will deliver the 2021 Max Perutz Lecture: ‘The coming of age of de novo protein design.’
LMB honoured in Cambridge Independent Science and Technology Awards
The LMB has received a Special Commendation in the category of Covid-19 Response Award, in the Cambridge Independent Science and Technology Awards. Also highly commended was Zunlong Ke, from John Briggs’ group in our Structural Studies Division, in the category of Researcher of the Year. More…
Repeating peptides are obstacles to neuronal transport in motor neurone disease
Repetitive peptides from the C9orf72 gene contribute to the most prevalent form of motor neurone disease, but it has been unclear how. Simon Bullock’s group help show how these peptides bind to both motor proteins and microtubule tracks to block neuronal transport.
Why humans have such big brains
The Guardian covers how Madeline Lancaster’s group in the Cell Biology division has used brain organoids to trace the origin of human’s larger brain size to the ZEB2 gene, which ‘switches on’ in early cerebral development. More…