Linda Amos, former Group Leader in the LMB’s Structural Studies Division, died on Sunday 21st February 2021. Linda was an excellent electron microscopist, at the forefront of image analysis and reconstruction.
Linda Amos (1943 – 2021)
Packaging molecular motors for delivery
The airways in our lungs are kept clear of mucus by the rhythmic beating motion of slender cellular extensions called cilia, driven by dynein motors. Andrew Carter’s group, has discovered a novel protein that packages these molecular motors for delivery into the cilia.
“A journey of small steps” – celebrating Women in Science at the LMB
For the International Day of Women and Girls in Science, we’ve asked a few of our researchers to tell us how and why they ended up in careers in science.
The race to repurpose nature’s protein factories
A C&EN feature about research aiming to enable ribosomes to make new drugs and materials through use of a wider variety of substrates, including key work by Jason Chin’s group to evolve orthogonal engineered ribosomes that function separately alongside natural ribosomes. More…
Targeting RNA replication in SARS-CoV-2
Chris Russo’s, David Barford’s, Jan Löwe’s, and John Sutherland’s groups have together solved the structure of the inhibitor favipiravir-RTP in complex with the SARS-CoV-2 RNA-dependent RNA polymerase, providing new insight into its mechanism of action.
Furin protease is not essential for SARS-CoV-2 infection
Scientists had thought that the protease furin was responsible for cleavage of the SARS-CoV-2 Spike protein to reveal the fusion machinery that enables infection, but new work from Leo James’ group shows that furin is not essential for SARS-CoV-2 infection.