Suyang Zhang’s group, in the LMB’s Structural Studies Division, has elucidated how the DNA helicase RECQL5 works with the transcription-coupled DNA repair complex to brake and accelerate RNA polymerase II transcription to maintain genome stability.
How RECQL5 applies the brakes to speeding RNA polymerase II to safeguard genome stability
Alan Fersht and Wes Robertson discuss the past, present and future of protein studies
The Naked Scientists podcast covers all things protein, including speaking to Alan Fersht and Wes Robertson from the LMB’s PNAC Division. They cover how early advances at the LMB revolutionised the field of protein studies, and how protein design could be developed to address key concerns in health and the environment. More…
Juliette Fedry is a Finalist in Eppendorf Award for Young European Investigators
Juliette Fedry, Group Leader in the LMB’s Cell Biology Division, has been recognised for her research into cellular proteostasis processes in health and disease.
Matt Higgins and Clemens Plaschka elected to EMBO Membership
Higgins: LMB 1997-2007, PhD student; Postdoctoral Scientist, Neurobiology; Structural StudiesPlaschka: LMB 2016-2018, Postdoctoral Visitor and Scientist, Structural Studies Congratulations to alumni Matt Higgins and Clemens Plaschka who have both been elected to EMBO Membership. Matt now leads a research group at the Department of Biochemistry, University of Oxford and Clemens is a Senior Group Leader […]
Architecture of the disease-prone GluA3 receptor unlocks new avenues for drug design
Ingo Greger’s group, in the LMB’s Neurobiology Division, discover that the GluA3 AMPAR adopts a structural organization that substantially diverges from all the other AMPA receptors.
First patient treated for APDS, a rare inherited disorder identified by collaborative Cambridge team including Roger Williams’s group
In 2013, Roger Williams’s group in the LMB’s PNAC Division published findings from a study conducted with researchers at the University of Cambridge, the Babraham Institute and clinicians from Addenbrooke’s Hospital. Together, the team identified a rare genetic mutation which causes a condition now known as Activated PI3K-d Syndrome (APDS), which weakens the immune system […]