Rocha J. J., Jayaram S. A., Stevens T. J., Muschalik N., Shah R. D., Emran S., Robles C., Freeman M., Munro S.
Functional unknomics: Systematic screening of conserved genes of unknown function
Plos Biology 21(8):e3002222DOI: doi.org/10.1371/journal.pbio.3002222
PMID: 37552676
PMCID: PMC10409296
Date of Paper: 08/08/2023
Division: Cell BiologyArseni D., Chen R., Murzin A. G., Peak-Chew S. Y., Garringer H. J., Newell K. L., Kametani F., Robinson A. C., Vidal R., Ghetti B., Hasegawa M., Ryskeldi-Falcon B.
TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP
Nature 620(7975):898-903DOI: 10.1038/s41586-023-06405-w
PMID: 37532939
PMCID: PMC10447236
Date of Paper: 02/08/2023
Division: NeurobiologySuskiewicz M. J., Munnur D., Strømland Ø., Yang J. C., Easton L. E., Chatrin C., Zhu K., Baretić D., Goffinont S., Schuller M., Wu W. F., Elkins J. M., Ahel D., Sanyal S., Neuhaus D., Ahel I.
Updated protein domain annotation of the PARP protein family sheds new light on biological function
Nucleic Acids Research 51(15):8217-8236DOI: 10.1093/nar/gkad514
PMID: 37326024
PMCID: PMC10450202
Date of Paper: 01/08/2023
Division: Structural StudiesSchofield P., Taylor A. I., Rihon J., Peña Martinez C. D., Zinn S., Mattelaer C. A., Jackson J., Dhaliwal G., Schepers G., Herdewijn P., Lescrinier E., Christ D., Holliger P.
Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif
Nucleic Acids Research 51(15):7736-7748DOI: 10.1093/nar/gkad592
PMID: 37439359
PMCID: PMC10450178
Date of Paper: 01/08/2023
Division: Protein & Nucleic Acid ChemistryHöpfler M, Hegde R. S.
Control of mRNA fate by its encoded nascent polypeptide
Molecular Cell 83(16):2840-2855DOI: 10.1016/j.molcel.2023.07.014
PMID: 37595554
PMCID: PMC10501990
Date of Paper: 01/08/2023
Division: Cell BiologyOzturk S. F., Sasselov D. D., Sutherland J. D.
The central dogma of biological homochirality: How does chiral information propagate in a prebiotic network?
The Journal of Chemical Physics 159(6):061102DOI: 10.1063/5.0156527
PMID: 37551802
PMCID: PMC7615580
Date of Paper: 01/08/2023
Division: Protein & Nucleic Acid ChemistryDendooven T., Zhang Z., Yang J., McLaughlin S. H., Schwab J., Scheres S. H. W., Yatskevich S., Barford D.
Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere
Science Advances 9(30):eadg7480DOI: doi.org/10.1126/sciadv.adg7480
PMID: 37506202
PMCID: PMC10381965
Date of Paper: 28/07/2023
Division: Structural StudiesJones M. L, Aria V., Baris Y., Yeeles J. T. P.
How Pol α-primase is targeted to replisomes to prime eukaryotic DNA replication
Molecular Cell 83(16):2911-2924.e16DOI: 10.1016/j.molcel.2023.06.035
PMID: 37506699
PMCID: PMC10501992
Date of Paper: 27/07/2023
Division: Protein & Nucleic Acid ChemistryDe-Souza E. A., Thompson M. A., Taylor R. C
Olfactory chemosensation extends lifespan through TGF-β signaling and UPR activation
Nature Aging 3(8):938-947DOI: 10.1038/s43587-023-00467-1
PMID: 37500972
PMCID: MC10432268
Date of Paper: 27/07/2023
Division: NeurobiologyHadjicharalambous A, Whale AJ, Can G, Skehel MJ, Houseley JM, Zegerman P
Checkpoint kinase interaction with DNA polymerase alpha regulates replication progression during stress
Wellcome Open Research 8:327DOI: 10.12688/wellcomeopenres.19617.1
PMID: 37766847
PMCID: PMC10521137
Date of Paper: 26/07/2023
Division: Cell BiologyServettini I., Talani G., Megaro A., Setzu M. D., Biggio F., Briffa M., Guglielmi L., Savalli N., Binda F., Delicata F., Bru-Mercier G., Vassallo N., Maglione V., Cauchi R. J., Di Pardo A., Collu M., Imbrici P., Catacuzzeno L, D'Adamo M. C., Olcese R., Pessia M.
An activator of voltage-gated K(+) channels Kv1.1 as a therapeutic candidate for episodic ataxia type 1
Proceedings of the National Academy of Sciences of the United States of America 120(31):e2207978120DOI: 10.1073/pnas.2207978120
PMID: 37487086
PMCID: PMC10401004
Date of Paper: 24/07/2023
Division: Cell BiologyYagita Y., Zavodszky E., Peak-Chew S. Y., Hegde R. S.
Mechanism of orphan subunit recognition during assembly quality control
Cell 186(16):3443-3459.e24DOI: 10.1016/j.cell.2023.06.016
PMID: 37480851
PMCID: PMC10501995
Date of Paper: 21/07/2023
Division: Cell BiologyHelfinger L, Tate CG.
Structures of Adrenoceptors
Handbook of Experimental Pharmacology (Book) 10.1007/164_2023_674DOI: 10.1007/164_2023_674
PMID: 37460660
PMCID:
Date of Paper: 18/07/2023
Division: Structural StudiesBeattie A.T., Dunkelmann D. L., Chin J. W.
Quintuply orthogonal pyrrolysyl-tRNA synthetase/tRNA(Pyl) pairs
Nature Chemistry 15(7):948-959DOI: doi.org/10.1038/s41557-023-01232-y
PMID: 37322102
PMCID: PMC7615293
Date of Paper: 15/07/2023
Division: Protein & Nucleic Acid ChemistryRitson D. J., Sutherland J. D.
Thiophosphate photochemistry enables prebiotic access to sugars and terpenoid precursors
Nature Chemistry 15(10):1470-1477DOI: 10.1038/s41557-023-01251-9
PMID: 37443293
PMCID: PMC10533393
Date of Paper: 13/07/2023
Division: Protein & Nucleic Acid ChemistryTarutani A., Lövestam S., Zhang X., Kotecha A., Robinson A. C., Mann D.M. A., Saito Y., Murayama S., Tomita T., Goedert M., Scheres S. H. W., Hasegawa M.
Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration
FEBS Open bio 13(8):1394-1404DOI: 10.1002/2211-5463.13657
PMID: 37337995
PMCID: PMC10392052
Date of Paper: 07/07/2023
Division: Structural StudiesDr. Falk Wachowius, Dr. Benjamin T. Porebski, Dr. Christopher M. Johnson, Dr. Philipp Holliger
Emergence of ATP- and GTP-Binding Aptamers from Single RNA Sequences by Error-Prone Replication and Selection
Chemsystemschem 5(5):syst.202300006DOI: 10.1002/syst.202300006
PMID: 38074198
PMCID: PMC7615363
Date of Paper: 02/07/2023
Division: Protein & Nucleic Acid ChemistryJou E.
Type 1 and type 2 cytokine-mediated immune orchestration in the tumour microenvironment and their therapeutic potential
Exploration of Targeted Anti-tumor Therapy 4(3):474-497DOI: 10.37349/etat.2023.00146
PMID: 37455828
PMCID: PMC10345208
Date of Paper: 30/06/2023
Division: Protein & Nucleic Acid ChemistryZürcher J. F, Kleefeldt A. A, Funke L. F. H, Birnbaum J, Fredens J, Grazioli S, Liu K. C., Spinck M., Petris G., Murat P., Rehm F. B. H, Sale J. E, Chin J. W.
Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly
Nature 619(7970):555-562DOI: 10.1038/s41586-023-06268-1
PMID: 37380776
PMCID: PMC7614783
Date of Paper: 28/06/2023
Division: Protein & Nucleic Acid ChemistryGunnarsson P. A., Babu M. M.
Predicting evolutionary outcomes through the probability of accessing sequence variants
Science Advances 9(30):eade2903DOI: doi.org/10.1126/sciadv.ade2903
PMID: 37506212
PMCID: PMC10381947
Date of Paper: 28/06/2023
Division: Structural StudiesLutton J. E., Coker H. L. E.., Paschke P., Munn C. J., King J. S., Bretschneider T., Kay R. R.
Formation and closure of macropinocytic cups in Dictyostelium
Current Biology 3(15):3083-3096.e6DOI: 10.1016/j.cub.2023.06.017
PMID: 37379843
PMCID: PMC7614961
Date of Paper: 27/06/2023
Division: Protein & Nucleic Acid ChemistryBaden T., Briseño J., Coffing G., Cohen-Bodénès S., Courtney A., Dickerson D., Dölen G., Fiorito G., Gestal C., Gustafson T., Heath-Heckman E., Hua Q., Imperadore P., Kimbara R., Król M., Lajbner Z., Lichilín N., Macchi F., McCoy M. J., Nishiguchi M. K., Nyholm S. V., Otjacques E., Pérez-Ferrer P. A., Ponte G., Pungor J. R., Rogers T. F., Rosenthal J. J. C., Rouressol L., Rubas N., Sanchez G., Santos C. P., Schultz D. T., Seuntjens E., Songco-Casey J. O., Stewart I. E., Styfhals R., Tuanapaya S., Vijayan N., Weissenbacher A., Zifcakova L., Schulz G., Weertman W., Simakov O., Albertin C.
Cephalopod-omics: Emerging Fields and Technologies in Cephalopod Biology
Integrative and Comparative Biology icad087 volume 0, pp. 1–14DOI: 10.1093/icb/icad087
PMID: 37370232
PMCID: PMC10755191
Date of Paper: 27/06/2023
Division: NeurobiologyGanguli S., Wyatt T., Nyga A., Lawson R. H., Meyer T., Baum B., Matthews H. K.
Oncogenic Ras deregulates cell-substrate interactions during mitotic rounding and respreading to alter cell division orientation
Current Biology 33(13):2728-2741.e3DOI: doi.org/10.1016/j.cub.2023.05.061
PMID: 37343559
PMCID: PMC7614879
Date of Paper: 26/06/2023
Division: Cell BiologySchweighauser M., Garringer H. J., Klingstedt T., Nilsson K. P. R., Masuda-Suzukake M., Murrell J. R., Risacher S L., Vidal R., Scheres S. H. W., Goedert M., Ghetti B., Newell K. L.
Mutation ∆K281 in MAPT causes Pick's disease
Acta Neuropathologica 146(2):211-226DOI: doi.org/10.1007/s00401-023-02598-6
PMID: 37351604
PMCID: PMC10329087
Date of Paper: 23/06/2023
Division: Structural StudiesRodríguez-Silvestre P., Laub M., Krawczyk P. A, Davies A. K., Schessner J.P., Parveen R., Tuck B. J., McEwan W. A., Borner G. H. H, Kozik P.
Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells
Science 380(6651):1258-1265DOI: doi.org/10.1126/science.adg8802
PMID: 37347855
PMCID: PMC7614779
Date of Paper: 22/06/2023
Division: Protein & Nucleic Acid Chemistry