Rzechorzek N. M., O'Neill J. S.
Healthy human brains have a daily heatwave
Temperature (Austin, Tex.) 10(2):155-158DOI: 10(2):155-158
PMID: 37325254
PMCID: PMC7614663
Date of Paper: 01/04/2023
Division: SecondryVytautė Boreikaitė., Lori A. Passmore
3'-End Processing of Eukaryotic mRNA: Machinery, Regulation, and Impact on Gene Expression
Annual Review of Biochemistry 92:199-225DOI: 10.1146/j.sbi.2023.102574
PMID: 37001138
PMCID: PMC7614891
Date of Paper: 31/03/2023
Division: Structural StudiesBoreikaitė V., Passmore L. A.
3'-End Processing of Eukaryotic mRNA: Machinery, Regulation, and Impact on Gene Expression
Annual Review of Biochemistry 92:199-225DOI: 10.1146/annurev-biochem-052521-012445
PMID: 37001138
PMCID: PMC7614891
Date of Paper: 31/03/2023
Division: Structural StudiesBoreikaitė V., Passmore L. A.
3'-End Processing of Eukaryotic mRNA: Machinery, Regulation, and Impact on Gene Expression
Annual Review of Biochemistry 92:199-225DOI: 10.1146/annurev-biochem-052521-012445
PMID: 37001138
PMCID: PMC7614891
Date of Paper: 31/03/2023
Division: Structural StudiesMukadam A. S., Miller L. V. C., Smith A. E., Vaysburd M., Sakya S. A, Sanford S., Keeling S., Tuck B. J., Katsinelos T., Green C., Skov L., Kaalund S. S., Foss S., Mayes K., O'Connell K., Wing M., Knox C., Banbury J., Avezov E., Rowe J.B, Goedert M., Andersen J.T, James LC., McEwan W.A.
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models
Science 379(6639):1336-1341DOI: 10.1126/science.abn1366
PMID: 36996217
PMCID: PMC7614512
Date of Paper: 30/03/2023
Division: NeurobiologyWagstaff J. M., Planelles-Herrero V. J., Sharov G., Alnami A., Kozielski F., Derivery E., Löwe J.
Diverse cytomotive actins and tubulins share a polymerization switch mechanism conferring robust dynamics
Science Advances 9(13):eadf3021DOI: 10.1126/sciadv.adf3021
PMID: 36989372
PMCID: PMC10058229
Date of Paper: 29/03/2023
Division: Structural StudiesShah P. N. M., Gilchrist J. B., Forsberg B. O., Burt A., Howe A., Mosalaganti S., Wan W., Radecke J., Chaban Y., Sutton G., Stuart D. I., Boyce M.
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography
Cell Host & Microbe 31(4):604-615.e4DOI: 10.1016/j.chom.2023.03.004
PMID: 36996819
PMCID: PMC7615348
Date of Paper: 29/03/2023
Division: Structural StudiesPapa G., Albecka A., Mallery D., Vaysburd M., Renner N., James L. C.
IP6-stabilised HIV capsids evade cGAS/STING-mediated host immune sensing
EMBO Reports 24(5):e56275DOI: 10.15252/embr.202256275
PMID: 36970882
PMCID: PMC10157305
Date of Paper: 27/03/2023
Division: Protein & Nucleic Acid ChemistryRamakrishnan L
Redefining tuberculosis: an interview with Lalita Ramakrishnan
Disease Models and Mechanisms 16(3):dmm050189DOI: 10.1242/dmm.050189
PMID: 36951140
PMCID: PMC10073006
Date of Paper: 23/03/2023
Division: Cell BiologyGusach A., García-Nafría J., Tate C. G.
New insights into GPCR coupling and dimerisation from cryo-EM structures
Current Opinion in Structural Biology 80:102574DOI: 10.1016/j.sbi.2023.102574
PMID: 36963163
PMCID: PMC10423944
Date of Paper: 22/03/2023
Division: Structural StudiesMühleip A., Flygaard R. K., Baradaran R., Haapanen O., Gruhl T., Tobiasson V., Maréchal A., Sharma V., Amunts A.
Structural basis of mitochondrial membrane bending by the I-II-III(2)-IV(2) supercomplex
Nature 615(7954): 934–938.DOI: 10.1038/s41586-023-05817-y
PMID: 36949187
PMCID: PMC10060162
Date of Paper: 22/03/2023
Division: NeurobiologyGarner K. E. L., Salter A., Lau C. K., Gurusaran M., Villemant C. M., Granger E. P., McNee G., Woodman P. G., Davies O. R., Burke B. E., Allan V. J.
The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein
222(5):e202204042 222(5):e202204042DOI: 10.1083/jcb.202204042
PMID: 36946995
PMCID: PMC10071310
Date of Paper: 22/03/2023
Division: Structural StudiesGusach A., García-Nafría J., Tate C. G.
New insights into GPCR coupling and dimerisation from cryo-EM structures
Current Opinion in Structural Biology PMC10423944DOI: 10.1016/j.sbi.2023.102574
PMID: 36963163
PMCID: PMC10423944
Date of Paper: 22/03/2023
Division: Structural StudiesMiroshnikova Y. A., Shahbazi M. N., Negrete J., Chalut K.J., Smith A.
Cell state transitions: catch them if you can
Development 150(6):dev201139DOI: 10.1242/dev.201139
PMID: 36930528
PMCID: PMC10655867
Date of Paper: 17/03/2023
Division: Cell BiologyHurtig F., Burgers T. C. Q., Cezanne A., Jiang X., Mol F.N., Traparić J., Pulschen A.A., Nierhaus T., Tarrason-Risa G., Harker-Kirschneck L., Löwe J., Šarić A., Vlijm R., Baum B.
The patterned assembly and stepwise Vps4-mediated disassembly of composite ESCRT-III polymers drives archaeal cell division
Science Advances 9(11):eade5224DOI: 10.1126/sciadv.ade5224
PMID: 36921039
PMCID: PMC10017037
Date of Paper: 15/03/2023
Division: Cell BiologyWinding M., Pedigo B. D, Barnes C. L, Patsolic H. G., Park Y., Kazimiers T., Fushiki A., Andrade I.V., Khandelwal A., Valdes-Aleman J., Li F., Randel N., Barsotti E., Correia A., Fetter R.D., Hartenstein V., Priebe C. E., Vogelstein J. T., Cardona A., Zlatic M.
The connectome of an insect brain
Science 379(6636):eadd9330DOI: 10.1126/science.add9330
PMID: 36893230
PMCID: PMC7614541
Date of Paper: 10/03/2023
Division: NeurobiologyLimar S, Körner C, Martínez-Montañés F, Stancheva VG, Wolf VN, Walter S, Miller EA, Ejsing CS, Galassi VV, Fröhlich F
Yeast Svf1 binds ceramides and contributes to sphingolipid metabolism at the ER cis-Golgi interface
Journal of Cell Biology 222(5):e202109162.DOI: 10.1083/jcb.202109162
PMID: 36897280
PMCID: PMC10038888
Date of Paper: 10/03/2023
Division: Cell BiologyLee H, Ciabatti E, González-Rueda A, Williams E, Nugent F, Mookerjee S, Morgese F, Tripodi M
Combining long-term circuit mapping and network transcriptomics with SiR-N2c
Nature Methods 20(4):580-589DOI: 10.1038/s41592-023-01787-1
PMID: 36864202
PMCID: PMC7614628
Date of Paper: 02/03/2023
Division: NeurobiologyVelazhahan V., McCann B. L., Bignell E., Tate C. G.
Developing novel antifungals: lessons from G protein-coupled receptors
Trends in Pharmacological Sciences 44(3):162-174DOI: 10.1016/j.tips.2022.12.002
PMID: 36801017
PMCID: PMC7614568
Date of Paper: 01/03/2023
Division: Structural StudiesPaul D., Stern O., Vallis., Dhillon J., Buchanan A., McMahon H
Cell surface protein aggregation triggers endocytosis to maintain plasma membrane proteostasis
Nature Communications 14(1):947DOI: 10.1038/s41467-023-36496-y
PMID: 36854675
PMCID: PMC9974993
Date of Paper: 28/02/2023
Division: NeurobiologyMalinverni D., Babu M.M.
Data-driven design of orthogonal protein-protein interactions
Science Signaling 16(774):eabm4484DOI: 10.1126/scisignal.abm4484
PMID: 36853962
PMCID: PMC7614567
Date of Paper: 28/02/2023
Division: Structural StudiesYang Y., Garringer H. J., Shi Y., Lövestam S., Peak-Chew S., Zhang X., Kotecha A., Bacioglu M., Koto A., Takao M., Spillantini M. G., Ghetti B., Vidal R., Murzin A. G., Scheres S. H. W., Goedert M.
New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy
Acta Neuropathologica 145(5):561-572DOI: 0.1007/s00401-023-02550-8
PMID: 36847833
PMCID: PMC10119069
Date of Paper: 27/02/2023
Division: Structural StudiesRathinaswamy M. K., Jenkins M. L., Duewell B. R., Zhang X., Harris N. J., Evans J. T., Stariha J. T. B., Dalwadi U., Fleming K. D., Ranga-Prasad H., Yip C. K., Williams R. L., Hansen S. D., Burke J. E.
Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs
Cell Reports 42(3):112172DOI: PMC10068899
PMID: 36842083
PMCID: PMC10068899
Date of Paper: 26/02/2023
Division: Protein & Nucleic Acid ChemistryLu C., Zaucha J., Gam R., Fang H., Ben Smithers., Oates M. E., Bernabe-Rubio M., Williams J., Zelenka N., Pandurangan A.P., Tandon H., Shihab H., Kalaivani R., Sung M., Sardar A.J., Tzovoras B.G., Danovi D., Gough J.
Hypothesis-free phenotype prediction within a genetics-first framework
Nature communications 14(1):919DOI: 10.1038/s41467-023-36634-6
PMID: 36808136
PMCID: PMC9938118
Date of Paper: 17/02/2023
Division: Structural StudiesThompson MA, De-Souza EA
A Year at the Forefront of Proteostasis and Aging
Biology Open 12(2):bio059750DOI: 10.1242/bio.059750
PMID: 36794708
PMCID: PMC9943145
Date of Paper: 16/02/2023
Division: Neurobiology