Luptak J., Mallery D. L., Jahun A. S., Albecka A., Clift D., Ather O., Slodkowicz G., Goodfellow I., James L. C.
TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing
Viruses 14(8):1610. 23 July 2022DOI: 10.3390/v14081610
PMID: 35893676
PMCID: PMC9394474
Date of Paper: 23/07/2022
Division: Protein & Nucleic Acid ChemistryGuilbaud G., Murat P., Wilkes H. S., Lerner L. K., Sale J. E., Krude T.
Determination of human DNA replication origin position and efficiency reveals principles of initiation zone organisation
Nucleic Acids Research 50(13):7436-7450. 22 July 2022DOI: 10.1093/nar/gkac555
PMID: 35801867
PMCID: PMC9303276
Date of Paper: 22/07/2022
Division: Protein & Nucleic Acid ChemistryGiachello C. N. G., Hunter I., Pettini T., Coulson B., Knufer A., Cachero S., Winding M., Arzan Zarin A., Kohsaka H., Fan Y. N., Nose A., Landgraf M., Baines R. A.
Electrophysiological validation of monosynaptic connectivity between premotor interneurons and the aCC motoneuron in the Drosophila larval CNS
Journal of Neuroscience e-pub: published online 20 July 2022DOI: 10.1523/jneurosci.2463-21.2022
PMID: 35868863
PMCID: PMC9435966
Date of Paper: 20/07/2022
Division: NeurobiologyBate N., Savva C. G., Moody P. C. E., Brown E. A., Evans S. E., Ball J. K., Schwabe J. W. R., Sale J. E., Brindle N. P. J.
In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding
Plos Pathogens 18(7):e1010733. 18 July 2022DOI: 10.1371/journal.ppat.1010733
PMID: 35849637
PMCID: PMC9333441
Date of Paper: 18/07/2022
Division: Protein & Nucleic Acid ChemistryPinar M, Alonso A, de Los Ríos V, Bravo-Plaza I, de la Gandara Á, Galindo A, Arias-Palomo E, Peñalva MÁ.
The type V myosin-containing complex HUM is a RAB11 effector powering movement of secretory vesicles
iScience Jun 2;25(7):104514DOI: 10.1016/j.isci.2022.104514
PMID: 35754728
PMCID: PMC9213775
Date of Paper: 15/07/2022
Division: Cell BiologyTossounian M. A., Baczynska M., Dalton W., Newell C., Ma Y., Das S., Semelak J. A., Estrin D. A., Filonenko V., Trujillo M., Peak-Chew S. Y., Skehel M., Fraternali F., Orengo C., Gout I.
Profiling the Site of Protein CoAlation and Coenzyme A Stabilization Interactions
Antioxidants 11(7):1362. 14 July 2022DOI: 10.3390/antiox11071362
PMID: 35883853
PMCID: PMC9312308
Date of Paper: 14/07/2022
Division: Cell BiologyRen J., Xue T., Wang L.
Shining more light on G protein signalling modules: a novel optogenetic tool for Gq activation
Science China. Life Sciences e-pub: published online 11 July 2022DOI: 10.1007/s11427-022-2150-1
PMID: 35831552
PMCID:
Date of Paper: 11/07/2022
Division: NeurobiologyRhymes E. R., Tosolini A. P., Fellows A. D., Mahy W., McDonald N. Q., Schiavo G.
Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons
Cell Death & Disease 13(7):584. 7 July 2022DOI: 10.1038/s41419-022-05031-0
PMID: 35798698
PMCID: PMC9263112
Date of Paper: 07/07/2022
Division: Structural StudiesKleist A. B., Jenjak S., Sente A., Laskowski L. J., Szpakowska M., Calkins M. M., Anderson E. I., McNally L. M., Heukers R., Bobkov V., Peterson F. C., Thomas M. A., Chevigné A., Smit M. J., McCorvy J. D., Babu M. M., Volkman B. F.
Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptor
Science 377(6602):222-228. 7 July 2022DOI: 10.1126/science.abj4922
PMID: 35857540
PMCID: PMC9574477
Date of Paper: 07/07/2022
Division: NeurobiologyGerlach K., Popp V., Wirtz S., Al-Saifi R., Gonzalez Acera M., Atreya R., Dregelis T., Vieth M., Fichtner-Feigl S., McKenzie A. N. J., Rosenbauer F., Weigmann B., Neurath M. F.
PU.1-driven Th9 cells promote colorectal cancer in experimental colitis models through IL-6 effects in intestinal epithelial cells
Journal of Crohn's & Colitis e-pub: published online 6 July 2022DOI: 10.1093/ecco-jcc/jjac097
PMID: 35793807
PMCID: PMC10197880
Date of Paper: 06/07/2022
Division: Protein & Nucleic Acid ChemistryFalk H. J., Tomita T., Mönke G., McDole K., Aulehla A..
Imaging the onset of oscillatory signaling dynamics during mouse embryo gastrulation
Development 149(13):dev200083. July 2022DOI: 10.1242/dev.200083
PMID: 35686648
PMCID: PMC9340547
Date of Paper: 01/07/2022
Division: Cell BiologyJanzen E, Shen Y, Vázquez-Salazar A, Liu Z, Blanco C, Kenchel J, Chen IA.
Emergent properties as by-products of prebiotic evolution of aminoacylation ribozymes
Nature Communications Jun 25;13(1):3631DOI: 10.1038/s41467-022-31387-0
PMID: 35752631
PMCID: PMC9233669
Date of Paper: 25/06/2022
Division: NeurobiologyRoca FJ, Whitworth LJ , Prag HA, Murphy MP, Ramakrishnan L
Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport
Science Jun 24;376(6600):eabh2841DOI: 10.1126/science.abh2841
PMID: 35737799
PMCID: PMC7612974
Date of Paper: 24/06/2022
Division: Cell BiologyMoris N., Shahbazi M.
Unravelling the mysteries of human embryogenesis
Seminars in Cell & Developmental Biology e-pub: published online 23 June 2022DOI: 10.1016/j.semcdb.2022.06.012
PMID: 35753909
PMCID:
Date of Paper: 23/06/2022
Division: Cell BiologyGadenne M. J., Hardege I., Yemini E., Suleski D., Jaggers P., Beets I., Schafer W. R., Chew Y. L.
Neuropeptide signalling shapes feeding and reproductive behaviours in male Caenorhabditis elegans
Life Science Alliance 5(10):e202201420. 23 June 2022DOI: 10.26508/lsa.202201420
PMID: 35738805
PMCID: PMC9233197
Date of Paper: 23/06/2022
Division: NeurobiologyKelkar M, Bohec P, Smith MB, Sreenivasan V, Lisica A, Valon L, Ferber E, Baum B, Salbreux G, Charras G.
Spindle reorientation in response to mechanical stress is an emergent property of the spindle positioning mechanisms
Proceedings of the National Academy of Sciences of the United States of America Jun 28;119(26):e2121868119DOI: 10.1073/pnas.2121868119
PMID: 35727980
PMCID: PMC9245638
Date of Paper: 21/06/2022
Division: Protein & Nucleic Acid ChemistryZhang R., Malinverni D., Cyr D. M., Rios P. L., Nillegoda N. B.
J-domain protein chaperone circuits in proteostasis and disease
Trends in Cell Biology e-pub: published online 18 June 2022DOI: 10.1016/j.tcb.2022.05.004
PMID: 35729039
PMCID:
Date of Paper: 18/06/2022
Division: Structural StudiesMuskhelishvili G, Sobetzko P, Travers A.
Spatiotemporal Coupling of DNA Supercoiling and Genomic Sequence Organization-A Timing Chain for the Bacterial Growth Cycle?
Biomolecules Jun 15;12(6):831DOI: 10.3390/biom12060831
PMID: 35740956
PMCID: PMC9221221
Date of Paper: 15/06/2022
Division: Cell BiologyToader B., Boulanger J., Korolev Y., Lenz M. O., Manton J., Schönlieb C. B., Mureşan L,
Image Reconstruction in Light-Sheet Microscopy: Spatially Varying Deconvolution and Mixed Noise
Journal of Mathematical Imaging and Vision 64(9):968-992. 14 June 2022DOI: 10.1007/s10851-022-01100-3
PMID: 36329880
PMCID: PMC7613773
Date of Paper: 14/06/2022
Division: Cell BiologyHatano T., Palani S., Papatziamou D., Salzer R., Souza D. P., Tamarit D., Makwana M., Potter A., Haig A., Xu W., Townsend D., Rochester D., Bellini D., Hussain H. M. A., Ettema T. J. G., Löwe J., Baum B., Robinson N. P., Balasubramanian M.
Asgard archaea shed light on the evolutionary origins of the eukaryotic ubiquitin-ESCRT machinery
Nature Communications 13(1):3398. 13 June 2022DOI: 10.1038/s41467-022-30656-2
PMID: 35697693
PMCID: PMC9192718
Date of Paper: 13/06/2022
Division: Structural Studies, Cell BiologyWilson LFL, Dendooven T, Hardwick SW, Echevarría-Poza A, Tryfona T, Krogh KBRM, Chirgadze DY, Luisi BF, Logan DT, Mani K, Dupree P.
The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis
Nature Communications Jun 8;13(1):3314DOI: 10.1038/s41467-022-31048-2
PMID: 35676258
PMCID: PMC9178029
Date of Paper: 08/06/2022
Division: Structural StudiesKaulich E., Carroll T., Ackley B., Tang Y. Q., Hardege I., Nehrke K., Schafer W. R., Walker D. S.
Distinct roles for two Caenorhabditis elegans acid-sensing ion channels in an ultradian clock
Elife e-pub: published online 6 June 2022DOI: 10.7554/elife.75837
PMID: 35666106
PMCID: PMC9374441
Date of Paper: 06/06/2022
Division: NeurobiologyLi P., Holliger P., Tagami S.
Hydrophobic-cationic peptides modulate RNA polymerase ribozyme activity by accretion
Nature Communications 13(1):3050. 3 June 2022DOI: 10.1038/s41467-022-30590-3
PMID: 35665749
PMCID: PMC9166800
Date of Paper: 03/06/2022
Division: Protein & Nucleic Acid ChemistryEiamthong B, Meesawat P, Wongsatit T, Jitdee J, Sangsri R, Patchsung M, Aphicho K, Suraritdechachai S, Huguenin-Dezot N, Tang S, Suginta W, Paosawatyanyong B, Babu MM, Chin JW, Pakotiprapha D, Bhanthumnavin W, Uttamapinant C.
Discovery and Genetic Code Expansion of a Polyethylene Terephthalate (PET) Hydrolase from the Human Saliva Metagenome for the Degradation and Bio-Functionalization of PET
Angewandte Chemie (International ed. in English) Sep 12;61(37):e202203061DOI: 10.1002/anie.202203061
PMID: 35656865
PMCID: PMC7613822
Date of Paper: 03/06/2022
Division: Protein & Nucleic Acid ChemistryJou E, Rodriguez-Rodriguez N, Ferreira AF, Jolin HE, Clark PA, Sawmynaden K, Ko M, Murphy JE, Mannion J, Ward C, Matthews DJ, Buczacki SJA, McKenzie ANJ.
An innate IL-25-ILC2-MDSC axis creates a cancer-permissive microenvironment for Apc mutation-driven intestinal tumorigenesis
Science Immunology Jun 3;7(72):eabn0175DOI: 10.1126/sciimmunol.abn0175
PMID: 35658010
PMCID: PMC7612821
Date of Paper: 03/06/2022
Division: Protein & Nucleic Acid Chemistry